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Phospho 4ebpl t37 46

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Phospho-4EBP1 (T37/46) is a primary antibody that recognizes the phosphorylated form of the 4E-binding protein 1 (4EBP1) at threonine residues 37 and 46. 4EBP1 is a key regulator of protein synthesis and its phosphorylation by mTOR is important for the control of cell growth and proliferation.

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Lab products found in correlation

Propidium iodine, by Thermo Fisher Scientific (2 mentions) Erlotinib, by Selleck Chemicals (2 mentions) Puromycin, by Thermo Fisher Scientific (2 mentions) Phospho egfr y1068, by Cell Signaling Technology (2 mentions) Ndrg1, by Cell Signaling Technology (2 mentions) Phospho ndrg1, by Cell Signaling Technology (2 mentions) Phospho tyrosine, by Cell Signaling Technology (2 mentions) Phospho s6, by Cell Signaling Technology (2 mentions) 4e bp1, by Cell Signaling Technology (2 mentions) Antibodies against β actin, by Merck Group (2 mentions) Rictor, by Cell Signaling Technology (2 mentions) Phospho akt, by Cell Signaling Technology (2 mentions) Hoechst 33342, by Thermo Fisher Scientific (2 mentions)

2 protocols using phospho 4ebpl t37 46

1

Erlotinib Signaling Pathway Analysis

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Erlotinib (#S1023) was obtained from Selleck Chemicals (Houston, TX, USA). Puromycin (#A1113803) was purchased from Life Technologies (Carlsbad, CA, USA). Hoechst 33342 (#H21492) and propidium iodine (#P1304MP) were acquired from Invitrogen (Waltham, MA, USA). The Rictor (#2114), phospho-tyrosine (#5465), phospho-NDRG1 (T346; #5482), NDRG1 (#9485), phospho-Akt (S473; #4060), Akt (#9272), phospho-S6 (S240/4; #2215), S6 (#2217), phospho-4EBPl (T37/46; #2855), 4EBP1 (#9452), phospho-EGFR (Y1068; #3777), EGFR (#4267) and MET (#8198) antibodies were from Cell Signaling Technologies (Danvers, MA, USA). Antibodies against β-actin (#A1978) were purchased from Sigma (St. Louis, MO, USA).
Chiang C.T., Demetriou A.N., Ung N., Choudhury N., Ghaffarian K., Ruderman D.L, & Mumenthaler S.M. (2018). mTORC2 contributes to the metabolic reprogramming in EGFR tyrosine-kinase inhibitor resistant cells in non-small cell lung cancer. Cancer letters, 434, 152-159.
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2

Erlotinib Signaling Pathway Analysis

Check if the same lab product or an alternative is used in the 5 most similar protocols
Erlotinib (#S1023) was obtained from Selleck Chemicals (Houston, TX, USA). Puromycin (#A1113803) was purchased from Life Technologies (Carlsbad, CA, USA). Hoechst 33342 (#H21492) and propidium iodine (#P1304MP) were acquired from Invitrogen (Waltham, MA, USA). The Rictor (#2114), phospho-tyrosine (#5465), phospho-NDRG1 (T346; #5482), NDRG1 (#9485), phospho-Akt (S473; #4060), Akt (#9272), phospho-S6 (S240/4; #2215), S6 (#2217), phospho-4EBPl (T37/46; #2855), 4EBP1 (#9452), phospho-EGFR (Y1068; #3777), EGFR (#4267) and MET (#8198) antibodies were from Cell Signaling Technologies (Danvers, MA, USA). Antibodies against β-actin (#A1978) were purchased from Sigma (St. Louis, MO, USA).
Chiang C.T., Demetriou A.N., Ung N., Choudhury N., Ghaffarian K., Ruderman D.L, & Mumenthaler S.M. (2018). mTORC2 contributes to the metabolic reprogramming in EGFR tyrosine-kinase inhibitor resistant cells in non-small cell lung cancer. Cancer letters, 434, 152-159.
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