Nvp auy 922

Manufactured by Chemietek

NVP AUY-922 is a laboratory instrument used for conducting research and analysis. The core function of this product is to provide a controlled environment for performing various experiments and tests. The detailed specifications and intended use of this product are not available at this time.

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Lab products found in correlation

Fbs rpmi, by Thermo Fisher Scientific (1 mentions) Alectinib, by Selleck Chemicals (1 mentions) Phoenix hek293 cells, by American Type Culture Collection (1 mentions) Accutase, by Innovative Cell Technologies (1 mentions) Y 27632, by Selleck Chemicals (1 mentions) Crystal violet, by Merck Group (1 mentions) Propidium iodide, by Merck Group (1 mentions) Oxaliplatin, by Merck Group (1 mentions) 17 aag, by Chemietek (1 mentions) Gemcitabine, by Bio-Techne (1 mentions) Es936, by Bio-Techne (1 mentions) Iodonitrotetrazolium violet, by Merck Group (1 mentions) 2 6 dichlorophenol indophenol dcpip, by Merck Group (1 mentions) Azd6244, by Chemietek (1 mentions) Nvp bez235, by Chemietek (1 mentions)

2 protocols using nvp auy 922

NSCLC Cell Line Establishment and Culture

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Human NSCLC H3122 cell lines were provided by Dr. William Pao (Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN) and confirmed to be free of Mycoplasma contamination. Cells were cultured in 10% FBS-RPMI (Invitrogen) medium at 37°C and 5% CO₂ in a humidified environment, digested with Accutase (Innovative Cell Technologies, Inc), and separated into single cells by passing through BD Falcon Cell Strainer (Sigma-Aldrich). Phoenix HEK293 cells used for producing lentivirus were obtained from ATCC (Manassas, VA). Crizotinib (PF 2341066) and NVP AUY-922, were purchased from ChemieTek (Indianapolis, IN). Alectinib and Y27632 were purchased from Selleck Chemicals.

Zhang G., Scarborough H., Kim J., Rozhok A.I., Chen Y.A., Zhang X., Song L., Bai Y., Fang B., Liu R.Z., Koomen J., Tan A.C., Degregori J, & Haura E.B. (2016). Coupling an EML4-ALK centric interactome with RNA interference identifies sensitizers to ALK inhibitors. Science signaling, 9(450), rs12.

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Evaluation of Small Molecule Inhibitors

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17-AAG (tanespimycin), NVP-AUY922, AZD6244, and NVP-BEZ235 were purchased from ChemieTek (Indianapolis, IN) and ES936 and gemcitabine from Tocris Bioscience (Bristol, United Kingdom), and each one of them is dissolved in DMSO or water. Propidium iodide, crystal violet, iodonitrotetrazolium violet, 4-hydroxycoumarin (dicumarol), 2,6-dichlorophenol-indophenol (DCPIP), and oxaliplatin were purchased from Sigma-Aldrich (St Louis, MO).

Mayor-López L., Tristante E., Carballo-Santana M., Carrasco-García E., Grasso S., García-Morales P., Saceda M., Luján J., García-Solano J., Carballo F., de Torre C, & Martínez-Lacaci I. (2014). Comparative Study of 17-AAG and NVP-AUY922 in Pancreatic and Colorectal Cancer Cells: Are There Common Determinants of Sensitivity?. Translational Oncology, 7(5), 590-604.

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