Diphenhydramine hydrochloride

Manufactured by Fujifilm

Sourced in Japan

Diphenhydramine hydrochloride is a laboratory chemical compound used in various research and analytical applications. It is a white crystalline powder that is soluble in water and other polar solvents. The primary function of diphenhydramine hydrochloride is as a chemical reagent for scientific and laboratory purposes, without any interpretation of its intended use.

Automatically generated - may contain errors

Lab products found in correlation

Spelling variants of this product

Diphenhydramine (2 citations)

4 protocols using diphenhydramine hydrochloride

Cultivation and Sourcing of Bioactive Compounds

Check if the same lab product or an alternative is used in the 5 most similar protocols

Fruit bodies of G. frondosa were cultivated by the Hokuto Corporation (Nagano, Japan). Ergosterol, histamine dihydrochloride, and diphenhydramine hydrochloride were purchased from Wako Pure Chemical Corporation (Osaka, Japan). Tranilast was purchased from Tokyo Chemical Industry Co., Ltd. (Tokyo, Japan). Dinitrophenyl-human serum albumin (DNP-HSA) and Ovalbumin (OVA) were purchased from Sigma-Aldrich (St. Louis, MO, USA).

Kawai J., Mori K, & Hirasawa N. (2019). Grifola frondosa extract and ergosterol reduce allergic reactions in an allergy mouse model by suppressing the degranulation of mast cells. Bioscience, biotechnology, and biochemistry, 83(12).

+ Open protocol

+ Expand

Pharmacological Compound Acquisition for Research

Check if the same lab product or an alternative is used in the 5 most similar protocols

Materials The following 47 compounds were purchased from Wako Pure Chemical Industries, Ltd., Osaka, Japan for use in this study: acetylsalicylic acid, acyclovir, allopurinol, amitriptyline, amoxicillin, azathioprine, azithromycin, budesonide, caffeine, carbamazepine, chloramphenicol, chlorpheniramine maleate salt, chlorpromazine, diethylcarbamazine, digoxin, diphenhydramine hydrochloride, doxycycline, erythromycin, ethosuximide, fluconazole, folic acid, furosemide, haloperidol, hydrochlorothiazide, hydrocortisone, ibuprofen, isoniazid, loratadine, metformin, metoclopramide, metronidazole, nitrofurantoin, ondansetron, oseltamivir, paracetamol, phenytoin, potassium iodide, prednisolone, primaquine, propranolol, propylthiouracil, quinine hydrochloride, salbutamol, spironolactone, sulfamethoxazole, valproic acid and vancomycin.

Haraguchi T., Okuno T., Nishikawa H., Kojima H., Ikegami S., Yoshida M., Habara M., Ikezaki H, & Uchida T. (2019). The Relationship between Bitter Taste Sensor Response and Physicochemical Properties of 47 Pediatric Medicines and Their Biopharmaceutics Classification. Chemical & pharmaceutical bulletin, 67(12).

+ Open protocol

+ Expand

Compound Characterization Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols

Materials Twenty-two compounds: acetaminophen, azathioprine, caffeine, chloramphenicol, chlorpheniramine maleate salt, colchicine, cromolyn sodium, dextromethorphan hydrobromide monohydrate, diphenhydramine hydrochloride, diphenidol hydrochloride, erythromycin, famotidine, flufenamic acid, haloperidol, hydrocortisone, methimazole, noscapine, ofloxacin, papaverine hydrochloride, propylthiouracil, quinine hydrochloride and strychnine nitrate were purchased from Wako Pure Chemical Industries, Ltd., Osaka, Japan.

Haraguchi T., Uchida T., Yoshida M., Kojima H., Habara M, & Ikezaki H. (2018). The Utility of the Artificial Taste Sensor in Evaluating the Bitterness of Drugs: Correlation with Responses of Human TASTE2 Receptors (hTAS2Rs). Chemical & pharmaceutical bulletin, 66(1).

+ Open protocol

+ Expand

Bitter Taste Masking Agents Assessment

Check if the same lab product or an alternative is used in the 5 most similar protocols

Materials Diphenhydramine hydrochloride (Wako Pure Chemical Industries, Ltd., Osaka, Japan), donepezil hydrochloride (Tokyo Chemical Industry Co., Tokyo, Japan), amlodipine besylate (LKT Labs, Inc., U.S.A.), etodolac (Wako Pure Chemical Industries, Ltd.), diclofenac (Wako Pure Chemical Industries, Ltd.) and rebamipide (Otsuka Pharmaceutical Co., Tokyo, Japan) were used as models of bitter drugs. Chlorogenic acid (CGA, 3-O-caffeoylquinic acid with a purity ≧95%) (Cayman Chemical Co., U.S.A.) was used as bitter taste masking agent.

Shiraishi S., Haraguchi T., Nakamura S., Li D., Kojima H., Yoshida M, & Uchida T. (2017). Taste-Masking Effect of Chlorogenic Acid (CGA) on Bitter Drugs Evaluated by Taste Sensor and Surface Plasmon Resonance on the Basis of CGA-Drug Interactions. Chemical & pharmaceutical bulletin, 65(2).

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!