Peak exercise capacity defined as peak oxygen consumption (peak V′O2) was determined using an incremental treadmill (Woodway PPS 55 Med; Woodway, Weil am Rhein, Germany) exercise test according to a modified Bruce protocol [29 (link)] using a Vyntus CPX unit powered by SentrySuite software (Vyaire Medical GmbH, Hoechberg, Germany). Speed and elevation increased every minute, starting from a slow walking phase, until the participants reached their maximum intensity level. The test was stopped when the participant indicated severe exhaustion or was unable to continue due to EILO symptoms, preferably supported by a respiratory exchange ratio (RER) exceeding 1.05 or heart rate exceeding 95% of maximally predicted [30 (link)]. Airflow and gas exchange parameters was measured breath-by-breath through a modified face mask (Hans Rudolph Inc., Kansas City, MO, USA) and averaged over 10 s. The cardiopulmonary exercise test (CPET) parameters recorded at maximal exhaustion are listed in table 1 .
Sentrysuite software
Manufactured by Vyaire Medical
Sourced in Germany
SentrySuite is a software platform that provides data management and reporting capabilities for respiratory care devices. It is designed to store, analyze, and generate reports from patient data collected by various medical equipment.
Automatically generated - may contain errors
Lab products found in correlation
5 protocols using sentrysuite software
1
Incremental Treadmill Exercise Test for Peak V'O2
2
Incremental Treadmill Test Protocol
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An incremental treadmill (Woodway PPS 55 Med, Weil am Rhein, Germany) test was applied, using a pre-set modified Bruce protocol [25 (link)]. Speed and elevation were gradually increased every 60 s from an initial slow walking phase. A facemask (Hans Rudolph Inc., Kansas City, MO, USA) connected the patient to a Vyntus CPX unit powered by SentrySuite software (Vyaire Medical GmbH, Leibnizstrasse, Hoechberg, Germany). After baseline variables were established, subjects ran to exhaustion. Parameters of gas exchange and airflow were measured breath-by-breath and averaged over 30 s.
The test was considered successful when the subjects indicated exhaustion, preferably supported by a plateau in V′O2 and/or the heart rate (HR) response. Duration and completed treadmill distance were recorded. V′O2, carbon dioxide output (V′CO2), tidal volume (VT), respiratory rate (RR) and HR were measured directly, while minute ventilation (V′E) was calculated from VT and RR.
The test was considered successful when the subjects indicated exhaustion, preferably supported by a plateau in V′O2 and/or the heart rate (HR) response. Duration and completed treadmill distance were recorded. V′O2, carbon dioxide output (V′CO2), tidal volume (VT), respiratory rate (RR) and HR were measured directly, while minute ventilation (V′E) was calculated from VT and RR.
3
Incremental Exercise Capacity Testing Protocol
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The mask size for each participant was chosen to insure headspace correction, and the Vyntus CPX gas analyzer (Model: versatile JAEGER; Vyaire medical, Hoechberg, Germany) was calibrated using the fully automated 2-point gas calibration of the O2/CO2, through a special Twin Tube sample line combined with a fresh air flush system [44 ]. The participants were tested on a motorized treadmill (Ergo ELG 55) that was connected to a programmable external WOODWAY User-System version 2.0 (Woodway GmbH, Weilam Rhein, Germany). The modified Bruce continuous incremental test protocol was used to test the participants [45 ]. The test continued until the participant could no longer continue the test (to exhaustion). Allometrically scaled [45 ,46 (link)] peak VO2 (VO2peak^0.67), respiratory exchange ratio (RER), breaths per minute (BPM), maximum heartrate (HRmax) and time to exhaustion were recorded using the breath-by-breath method powered by Vyaire’s SentrySuite software (Vyaire medical, Hoechberg, Germany). The following criteria had to be met for the measures to be accepted: (i) VO2 plateaued despite increased exercise intensity and (ii) RER > 1.0. Further methodological details are provided in the supplementary materials (S1: methodological details) .
4
Treadmill Exercise Test for VO2peak Evaluation
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Peak exercise capacity was determined using a computerized incremental treadmill (Woodway PPS 55 Med, Weil am Rhein, Germany) exercise test according to a modified Bruce protocol (19 (link)) using a Vyntus CPX unit powered by SentrySuite software (Vyaire Medical GmbH, Hoechberg, Germany). Speed and elevation were increased every 90 s from an initial slow-walking phase. The test was stopped when the subject indicated severe exhaustion, preferably supported by a respiratory exchange ratio (RER) exceeding 1.05 or heart rate exceeding 95% of predicted maximal heart rate (20 (link)).
Variables of gas exchange and airflow were measured breath by breath and averaged over 10 s. The highest values for oxygen uptake determined during the last 60 s were recorded as peak values (VO2peak). VO2peak was reported as ml/kg/min and as the percentage of predicted using reference equations from a large sample of Norwegian subjects of relevant age (21 (link)). Exercise performance was described by the completed distance (meters) on the treadmill. The percentage inspiratory time to total time in a respiratory cycle (Ti/Ttot%) was used to describe the breathing pattern. Breathing reserve was the difference between maximal voluntary ventilation (FEV1 x 35) and peak minute ventilation reported as the percentage of maximal voluntary ventilation.
Variables of gas exchange and airflow were measured breath by breath and averaged over 10 s. The highest values for oxygen uptake determined during the last 60 s were recorded as peak values (VO2peak). VO2peak was reported as ml/kg/min and as the percentage of predicted using reference equations from a large sample of Norwegian subjects of relevant age (21 (link)). Exercise performance was described by the completed distance (meters) on the treadmill. The percentage inspiratory time to total time in a respiratory cycle (Ti/Ttot%) was used to describe the breathing pattern. Breathing reserve was the difference between maximal voluntary ventilation (FEV1 x 35) and peak minute ventilation reported as the percentage of maximal voluntary ventilation.
5
Cardiopulmonary Metabolic Assessment Protocol
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Breath by breath data were measured using a pulmonary gas analyser (Vyntus™ ONE; Vyaire Medical, Mettawa, IL, USA) calibrated using certified gases (Gas 1: Ambient Air; Gas 2: 15% O2, 5% CO2) with data displayed for standardized temperature and pressure for dry air. Integrated heart rate data were recorded continuously via chest belt telemetry (Polar Electro, Finland). Raw cardiopulmonary data were exported in 5‐s intervals (SentrySuite™ software; Vyaire Medical) and subsequently averaged in 30‐s segments for statistical processing.
The peak rate of O2 consumption (V̇O2peak) was defined as highest O2 uptake (L/min) obtained in the 30 s before the test cessation. V̇O2peak was utilized over V̇O2max because of an inability to identify a plateau in some participants' O2 consumption rates because of the short duration of exercise test and/or volitional termination occurring rapidly upon attainment of peak power. All other cardiopulmonary and performance parameters were indexed to the V̇O2peak value. Using raw gas exchange data, the anaerobic threshold (AT) was computed via the Exercise Threshold App23 with other cardiopulmonary variables timed‐referenced against the indexed V̇O2 value.
The peak rate of O2 consumption (V̇O2peak) was defined as highest O2 uptake (L/min) obtained in the 30 s before the test cessation. V̇O2peak was utilized over V̇O2max because of an inability to identify a plateau in some participants' O2 consumption rates because of the short duration of exercise test and/or volitional termination occurring rapidly upon attainment of peak power. All other cardiopulmonary and performance parameters were indexed to the V̇O2peak value. Using raw gas exchange data, the anaerobic threshold (AT) was computed via the Exercise Threshold App
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