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221 protocols using hem 907

1

Automated Blood Pressure Measurement

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SBP and diastolic blood pressure (DBP) were measured using the Omron HEM-907 automatic blood pressure monitor (Omron HEM-907, Omron Healthcare, Inc., Veron Hills IL, USA). The children sat in a relaxed position in a quiet environment without distractions for ten minutes. Four measurements were taken at one-minute intervals on the upper right arm using an appropriately sized cuff, with the average of the final three measurements within 5 mmHg used in all analyses. If a difference > 5 mmHg between measurements was found, we obtained one extra measurement, in which case the average of the last four measurements was used.
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2

Standardized Clinic Blood Pressure Measurement

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Clinic BP was measured in each participant’s right arm following a standardized protocol, using a Hawksley random zero sphygmomanometer and Littman stethoscope. The appropriate cuff size was determined by measuring each participant’s right arm circumference. Two BP readings, separated by a one-minute rest, were obtained and averaged to define clinic SBP and DBP. The random-zero sphygmomanometer has been shown to under-estimate BP [13 (link)]. Therefore, the random-zero BP measurements were calibrated to a semi-automated device (Omron-HEM-907, Omron Healthcare Inc., Lake Forest, IL) using robust regression as described previously [14 ].
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3

Resting Cardiovascular Measurements

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After resting in the supine position for 10-min in a quiet room, resting BP and HR were measured in triplicate at the brachial artery using an automated oscillometric BP monitor (OMRON HEM-907, OMRON Corporation, Tokyo, Japan). The average of three measurements was used for analysis.
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4

Blood Pressure Measurement Protocol

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BP was measured using a digital blood pressure monitor (OMRON HEM-907; Omron Healthcare, Kyoto, Japan). Prior to having their measurements taken, participants were required to be in a seated position for 15 min, using an appropriately sized cuff with the artery indicator at the correct anatomical position. The BP monitor was set to take three measurements at one-minute intervals, and the average was recorded. The American Academy of Pediatrics cut off values were used to define elevated BP (≥120 mmHg systolic and <80 mmHg diastolic), and hypertension (>130/80 mmHg) [19 (link)].
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5

Vascular Function Monitoring Protocol

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All vascular measurements were performed in a darkened, quiet, temperature-controlled room, were recorded in triplicates, and the average was taken for subsequent statistical analysis. Brachial BP was recorded following a 10 minutes seated resting period, on the dominant arm using an automatic cuff oscillometric device (OMRON HEM-907, Omron Healthcare, Kyoto, Japan). Central AI and BP were recorded in a supine position at the radial artery obtained noninvasively by applanation tonometry using pulse wave analysis (SphygmoCor Vx, AtCor Medical, Sydney, AU). Measurements were recorded at baseline (0 minutes) and 60, 120, and 180 minutes following the intervention. AI measurements were recorded in a continuous, steady state over a period of 15 seconds and the same position was used for all subsequent measurements. Only values with an operator index > 80% were included in the analysis.
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6

Home-Based Blood Pressure Monitoring

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Patients enroled in Hypertension Objective Treatment based on Measurement by Electrical Device of Blood Pressure (HOMED-BP) received spoken and written instructions on blood pressure self-measurement and the utilisation of a validated cuff-oscillometric OMRON HEM 747IC-N (Omron Healthcare Co, Ltd, Kyoto, Japan),18 (link) in which all measured data, including the measurement time, are automatically recorded. The standard upper-arm cuff, which covered 22–32 cm of a patient’s arm circumference, was attached to the device. The importance of using an appropriately sized cuff was noted in the user’s manual of the device, and we provided another cuff on request. Throughout the study period, patients were asked to self-measure their blood pressure at home once every morning within 1 hour of awakening, after urination, before breakfast, before taking antihypertensive medication and after 2 min rest in a sitting position.
Office blood pressure was measured by doctors in the outpatient clinic using a validated cuff-oscillometric OMRON HEM-907 (Omron Healthcare Co, Ltd).19 (link) At each visit, the office blood pressure was measured twice consecutively in a sitting position after at least 2 min rest.
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7

Standardized Blood Pressure Measurement

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Blood pressure is measured via a digital blood pressure monitor (OMRON HEM-907; Omron Healthcare, Japan) placed on the non-dominant arm. Participants are requested to lie down in a dimly lit, temperature controlled (approximately 22–24 C) room. After 10 min of rest, the monitor takes three measurements with an interval of 2 minutes between each measurement. The monitor measures systolic pressure, diastolic pressure, and heart rate and determines the average of the three measurements separately. The three measurements, as well as the average values, are recorded.
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8

Validating Digital Blood Pressure Monitors

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Brachial arterial blood pressure will be measured in a seated position on the same arm during each trial using a mercurial sphygmomanometer (Japan site: MRP Automatic Cock System 605 P, KENZMEDICO Co., Saitama, Japan; Singapore site: Mercurial Sphygmomanometer CK-101C, Spirit Medical Co., Taipei, Taiwan) and a digital blood pressure monitor (all sites: OMRON HEM-907, Omron Healthcare Co., Kyoto, Japan). The ethnicity comparison will be conducted using the data collected from the same digital blood pressure monitor at all sites because devices containing mercury are prohibited in Europe. The concurrent measurement using the mercurial sphygmomanometer in Singapore and Japan will permit the validation of the data collected using the digital monitor. Participants will be seated on a chair for 10 min before each measurement. The average of two measures will be taken at each time point and the mean value recorded for statistical analysis.
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9

Validation of Blood Pressure Devices

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The Greenlight 300 (Accoson, Essex, United Kingdom) and Omron HEM-907 (Omron, Kyoto, Japan) devices have been validated based on the European Society of Hypertension protocol.[5 (link),6 (link)] To ensure the accuracy of the piezoresistive manometer, we performed the validation procedure described in our previous study.[7 (link)] In the present study, no difference more than 3 mmHg was observed for the 4 devices applied in the before- and after-use validation tests. Therefore, the previously defined validation criteria were fulfilled.[8 (link)] As the inter-device differences were not significant, the devices were not rotated among observers. No device malfunctions were observed.
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10

Sociodemographic and Anthropometric Factors

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The sociodemographic factors of participants were obtained using a pre-tested structured questionnaire. Anthropometric measurements including height, weight, and waist circumference were ascertained using standardized techniques [28 (link),29 ]. A universal surrogate measure of body weight status, body mass index (BMI), was computed as the ratio of weight (kg) to height2 (m2), and was classified according to the WHO (2000) [30 ]. The percentage of body fat of the participants was measured using the body fat monitor HBF-306 (Omron Matsusaka Co. Ltd., Matsusaka, Japan) with an accuracy of up to 0.1%. Blood pressure was assessed using a Digital Automatic BP monitor (OMRON HEM-907, Omron, Kyoto, Japan), while the physical activity level was obtained using the validated Global Physical Activity Questionnaire (GPAQ) [31 (link)]. The adequacy of physical activity among the participants was ascertained according to the recommendation by the WHO whereby an individual should perform more than 600 Metabolic Equivalent (MET) minutes of total physical activity per week, with MET (Metabolic Equivalent) defined as “the ratio of a person’s working metabolic rate relative to the resting metabolic rate” in the GPAQ analysis guide [32 ].
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