Achieva x series

This study was performed retrospectively. All data collected for clinical purpose were anonymous and the readers were the ones who performed all clinical examinations.
The study was approved by the Ethics Committee of the University “G. d’Annunzio” of Chieti—Pescara (Chieti, Italy)[26 (link)]. All patients or caregivers were aware that their data will be used for possible research purpose other than clinical diagnosis and they signed an informed consent.
The study included fourteen patients (11 men and 3 women; aged 33–78 years; mean age 62 years) presenting a single brain mass indistinguishable at conventional MRI and characterized by ring enhancement (Fig 1), peri-lesional edema, and absence of haemorrhage signs. None of the patients underwent surgery or biopsy before the MRI scan.
All lesions were histologically proven. 5 lesions were benign and all of them were pyogenic abscesses. 9 lesions were malignant and they included 6 GBMs, and 3 metastases.
All patient underwent the same advanced 3T MRI scan protocol.
MRI data were obtained with a 3T scanner (Philips Achieva X Series, Philips Medical System, Best, Netherlands) using a SENSE (Sensitivity Encoding) dedicated eight-channel head coil.
All patients underwent conventional and advanced MR techniques.

All MRI experiments were performed on a 3.0-Tesla whole-body MRI scanner (Philips Achieva X-series, Amsterdam, The Netherlands) using a dedicated phased array receiver coil for high-resolution MRI as previously described [22 (link)]. In brief, PC-3 cells (a prostate cancer cell line) pre-cultured for 24 h were incubated with various concentrations (0, 3.13, 6.25, 12.5, 25, and 50 μg/mL) of the CoFe₂O₄-HPs-FAs for 2 h in a 24-well culture plate. The cells were then fixed with a 2% glutaraldehyde and paraformaldehyde solution and mixed with a 1.5% agar solution in 1.5-mL micro-centrifuge tubes for MRI.

Resting-state fMRI data were acquired using an eight-channel 3.0-Tesla Philips MR scanner (Achieva X-series, the Netherlands) in the Department of Radiology, the Affiliated Brain Hospital of Guangzhou Medical University, China. The foam padding and earplugs were used to reduce head motion and to muffle scanner noise, respectively. During scanning, all the subjects were asked to stay awake, close their eyes, and think nothing. Resting-state fMRI data were scanned using an echo planar imaging sequence with the following parameters: repetition time = 2000 ms, echo time = 30 ms, flip angle = 90⁰, field of view = 220 × 220 mm², matrix = 64 × 64, 33 slices, slice thickness = 4 mm with 0.6 mm gap, and 240 volumes. The resting-state fMRI data have been used in our previous studies (Wu et al., 2016a (link); Wang et al., 2017a (link)).

Structural data were acquired using a 3.0-Tesla Philips scanner (Achieva X-series, Philips Medical Systems, the Netherlands) at the Affiliated Brain Hospital of Guangzhou Medical University. A sagittal three-dimensional gradient-echo T1-weighted sequence was performed. The acquisition parameters were repetition time (TR) = 8.2 ms, echo time (TE) = 3.7 ms, flip angle (FA) = 7°, inversion time (TI) = 1,100 ms, acquisition matrix = 256 × 256, field of view (FOV) = 256 mm² × 256 mm², axial slices = 188, slice thickness = 1 mm.

A subgroup of people with type 2 diabetes (n=18) underwent ¹H MR spectroscopy using a stimulated echo acquisition mode (STEAM) sequence in a 3-T MR scanner (Achieva X-series, Philips Healthcare, Best, Netherlands), to assess hepatocellular lipid content (24 (link)).

MR imaging was performed in all subjects using a 3.0 T scanner (Achieva X series, Philips Healthcare, Best, The Netherlands) equipped with 16‐channel SENSE‐XL‐Torso array coil. 3D spoiled chemical‐shift water‐fat mDixon sequence was used (TR = 5.7 ms, first TE/echo spacing = 1.2‐1.4 (ms)/1.0‐1.2 (ms), number of echoes = 6, flip angle = 3°, parallel imaging acceleration = 2, a 15 seconds breath hold technique was employed to acquire co‐registered water, fat, fat‐fraction and T2* image series and was reconstructed with slice thickness/number of slices = 3.0 mm/50. The field of view (FOV) covered the whole abdomen, that is, region from the dome of the diaphragm to the symphysis pubis. Image reconstruction was completed online using Philips mDixon product implementation with the multi‐peak spectral model of fat and T2* correction to increase accuracy and sensitivity.