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Acquity uplc h class sqd 2 system

Manufactured by Waters Corporation
Sourced in United States

The Acquity UPLC H-Class/SQD II system is a high-performance liquid chromatography (HPLC) instrument designed for efficient and accurate separation and analysis of chemical compounds. The system combines an Acquity UPLC H-Class module for liquid chromatography and an SQD II single quadrupole mass spectrometer for mass detection. This integrated system enables rapid and sensitive analysis of a wide range of samples.

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2 protocols using acquity uplc h class sqd 2 system

1

LC-ESI-MS Analysis of PEFA

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LC–ESI–MS analysis of PEFA was performed on a Waters Acquity UPLC H-Class/SQD II system (Waters Corp., Milford, MA, USA), equipped with an ACQUITY UPLC BEH Shield RP18 (100 mm × 2.1 mm, 1.7 μm) column. The chromatography separation was performed as described by Guerfali et al. [17 (link)]. The LC–MS instrument was operated in positive ion electrospray mode with an acquisition range of m/z 115–1700 with a scan rate of 0.5 spectra/s.
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2

HPLC-ESI-MS Analysis of Melanin-A

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HPLC–ESI–MS analysis of MEL-A was performed as a previously described method (Wang et al. 2019 (link)) on a Waters Acquity UPLC H-Class/SQD II system (Waters Corp., Milford, MA, USA) with an ACQUITY UPLC BEH Shield RP18 (100 mm × 2.1 mm, 1.7 μm) column. The MS detection was operated in positive ion electrospray mode with an acquisition range of m/z 50–1000 and a scan rate of 0.5 spectra/s. The mass spectral ions were identified by the calculation of elemental composition according to available literature (Goossens et al. 2016 (link)).
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