Labeled cells were detached and collected with 0.25% trypsin. Female NOD/scid immunodeficient mice (n = 6, 10 weeks old, Jackson Laboratory, Bar Harbor, ME) were anesthetized with 2% isoflurane. An incision was made to expose the left kidney of the mouse, then a catheter needle was inserted underneath the kidney capsule and cells labeled with 18F-FDG were transplanted.
Female nod scid immunodeficient mice
Manufactured by Jackson ImmunoResearch
Sourced in Montenegro, United States
Female NOD/scid immunodeficient mice are genetically engineered rodents that lack a functional immune system. They are commonly used in biomedical research as a model to study human diseases and test new therapies. These mice are deficient in both the innate and adaptive immune responses, making them highly susceptible to infections and well-suited for xenograft studies.
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Lab products found in correlation
2 protocols using female nod scid immunodeficient mice
1
Intrarenal Transplantation of Labeled Cells
2
Islet Organoid Transplantation in NOD/scid Mice
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All animal experiments were performed in compliance with institutional guidelines and were approved by the Institutional Animal Care and Use Committee (IACUC) at the Michigan State University. Labeled islet organoids were collected 1 h before transplantation. Female NOD/scid immunodeficient mice (n = 5, 10 weeks old, Jackson Laboratory, Bar Harbor, ME, United States) were anesthetized with 2% isoflurane. An incision made to expose the left kidney of the mouse, a catheter needle inserted underneath the kidney capsule and 800 islet organoids VivoTrax labeled were transplanted. Then the incision was closed, mice were monitored after transplantation.
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