Cobalt 2 chloride hexahydrate

Manufactured by Merck Group

Sourced in United States, Germany

Cobalt (II) chloride hexahydrate is an inorganic compound with the chemical formula CoCl2·6H2O. It is a crystalline solid that appears red-pink in color. The compound is soluble in water and is commonly used as a laboratory reagent and in various industrial applications.

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Close spelling variants of this product

Cobalt chloride (91 citations) Cobalt chloride hexahydrate (39 citations) Cobalt(II) chloride (36 citations) Cobalt (II) chloride hexahydrate (CoCl2.6H2O; (6 citations) Cobalt(II) chloride hexahydrate (CoCl2, (4 citations)

64 protocols using cobalt 2 chloride hexahydrate

Preparation of Electrochemical Characterization Samples

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Natural Kish graphite crystals were purchased
from Graphene Supermarket. Si/SiO₂ wafers (0.5 mm thick
with 285 nm SiO₂ or 90 nm SiO₂) were purchased
from NOVA Electronic Materials. Polydimethylsiloxane (PDMS)
stamps were purchased from MTI Corporation. Sn/In alloy was purchased
from Custom Thermoelectric. Poly(bisphenol A carbonate) (Mw 45 000),
dichlorodimethylsilane (>99.5%), hexaammineruthenium(III)
chloride (98%), cobalt(II) chloride hexahydrate (98%), 1,10-phenanthroline
(>99%), calcium chloride (>93%), and potassium chloride (>99%)
were
purchased from Sigma-Aldrich and used as received. All aqueous electrolyte
solutions were prepared with type I water (EMD Millipore, 18.2 MΩ
cm resistivity). The 2 mM solutions of tris(1,10-phenanthroline)cobalt(II)
were prepared by dissolving 1:3 molar ratios of solid cobalt(II) chloride
and 1,10-phenanthroline in water. In both Ru(NH₃)₆^3+/2+ and Co(phen)3³⁺ solutions, 0.1 M KCl was added as a supporting electrolyte.

Zhang K., Yu Y., Carr S., Babar M., Zhu Z., Kim B.J., Groschner C., Khaloo N., Taniguchi T., Watanabe K., Viswanathan V, & Bediako D.K. (2023). Anomalous Interfacial Electron-Transfer Kinetics in Twisted Trilayer Graphene Caused by Layer-Specific Localization. ACS Central Science, 9(6), 1119-1128.

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Synthesis of Fluorinated Benzonitrile Compounds

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4-Fluorobenzonitrile (Alfa Aesar), 4-aminobenzonitrile (Alfar Aesar), potassium nitrate, and cobalt(ii) chloride hexahydrate (Aldrich) were obtained commercially and used without further purification. All other chemicals were of AR grade.

Aphirakaramwong C., Akintola O., Plass C.T., Sawangphruk M., Plass W, & Balducci A. (2023). Improving the performance of an anionic MOF by counter cation replacement as electrode material in a full cell setup of a potassium ion capacitor. RSC Advances, 13(18), 12277-12284.

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Synthesis of Metal-Organic Composites

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Anhydrous ferric chloride (FeCl₃), iron (II) sulfate hexahydrate (FeSO₄·6H₂O), cobalt (II) chloride hexahydrate (CoCl₂·6H₂O), lead nitrate (Pb(NO₃)₂), citric acid monohydrate (C₆H₈O₇·H₂O) crystal, copper (II) sulfate pentahydrate (CuSO₄·5H₂O), acetic acid (CH₃COOH) glacial 100%, hydrochloric acid (HCl) fuming 37%, sodium hydroxide (NaOH) pellets, and absolute alcohol, were purchased from Merck, a German company. Formaldehyde (CH₃CHO) solution 37% by weight was purchased from Honeywell Riedel-de Haen Research Chemicals, a German company. Vanillin (C₈H₈O₃) was purchased from BDH Chemicals Ltd., a British company. Cadmium (II) sulfate (3CdSO₄·8H₂O), was purchased from Loba Chemie Pvt. Ltd., an Indian company. Sodium tripolyphosphate (Na₅P₃O₁₀) anhydrous extra pure was purchased from Sisco Research Laboratories Pvt. Ltd., an Indian company. All chemicals used in this research work were of analytical quality and used without further purification. Double-distilled water was used in all the studies for sample synthesis and washing purposes.

Chandra D., Molla M.T., Bashar M.A., Islam M.S, & Ahsan M.S. (2023). Chitosan-based nano-sorbents: synthesis, surface modification, characterisation and application in Cd (II), Co (II), Cu (II) and Pb (II) ions removal from wastewater. Scientific Reports, 13, 6050.

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Synthesis of Metal-Organic Complexes

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Citric
acid, mercury(II)
acetate, cobalt(II) chloride hexahydrate, nickel(II) chloride hexahydrate,
cadmium(II) chloride, copper(II) chloride dihydrate, iron(II) sulfate
heptahydrate, manganese(II) acetate tetrahydrate, lead nitrate, zinc(II)
sulfate heptahydrate, sodium chloride, and sodium hydroxide were purchased
from Merck, India. p-Phenylenediamine was purchased
from Loba Chemie, and terbium(III) chloride and dialysis bags (1 kDa)
were purchased from Sigma-Aldrich. All reagents were of analytical
grade and used without further purification. Milli-Q water was used
for all the experiments.

Mondal T.K., Ghorai U.K, & Saha S.K. (2018). Dual-Emissive Carbon Quantum Dot-Tb Nanocomposite as a Fluorescent Indicator for a Highly Selective Visual Detection of Hg(II) in Water. ACS Omega, 3(9), 11439-11446.

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Antioxidant Evaluation of Herbal Extracts

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Acetic acid, ethyl acetate, cobalt (II)-chloride hexahydrate, Folin–Ciocalteau reagent, gallic acid, glacial Acetic acid (C₂H₄O₂), hydrochloric acid and hydrogen peroxide (H₂O₂, 30%) were purchased from Merck (Germany). Boric acid (H₃BO₃), methanol, butanol, 2,2-diphenyl-1-picrylhydrazyl (DPPH), EDTA (ethylenediamine tetraAcetic acid), luminol (3-aminophtalylhydrazide), 2, 4, 6-tripyridyl-s-triazine (TPTZ), iron (III) chloride hexahydrate (FeCl₃·6H₂O), iron (II) sulfate heptahydrate (FeSO₄·7H₂O), sodium acetate trihydrate (C₂H₃NO₂), sodium carbonate, and sodium hydroxide were purchased from Sigma-Aldrich (Germany).

Benchennouf A., Grigorakis S., Loupassaki S, & Kokkalou E. (2016). Phytochemical analysis and antioxidant activity of Lycium barbarum (Goji) cultivated in Greece. Pharmaceutical Biology, 55(1), 596-602.

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HGAT Ophthalmic Formulation Analysis

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HGAT drug has a potency of 99.20 % (Batch No. JT20151102) was kindly supplied by Delta Grand Pharma. HGAT in its ophthalmic formulation as Tymer sample; 5 mL (0.3% sterile ophthalmic solution) labeled to be 3 mg HGAT/1mL (Batch No. WC0061) produced by Jamjoom Pharmaceuticals Co., Jeddah, Saudi Arabia. Cobalt (II) Chloride hexahydrate (Merck), nickel (II) chloride hexahydrate (Aldrich) and lanthanum (III) Chloride hexahydrate (Fluka). Hydrochloric, nitric and sulphuric acids in addition to lithium hydroxide monohydrate (EL-Nasr Chemical Co. Egypt). Ethanol 99.99 % (ADWIC). Disodium salt of ethylenediaminetetraacetic acid, Na₂-EDTA (Prolabo); ammonia solution 25% (Abco Chemie ENG. LTD); xylenol orange were analytical grade and were used as supplied. De-ionized water was used in the preparation of the required solutions.

Mostafa M.M., Abd El-Wahab Z.H., Salman A.A, & Abdelbaset W.M. (2021). The use of complex formation manner for spectrophotometric analysis of gatifloxacin drug based on Co(II), Ni(II) and La(III) ions. Heliyon, 7(1), e06051.

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Synthesis of Dye-Intercalated Montmorillonite

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Iron(III) chloride hexahydrate, cobalt(II) chloride
hexahydrate,
and sodium hydroxide were purchased from Merck Inc. Glycoluril, montmorillonite
K10 (Sigma-Aldrich), crystal violet (CV) (Sigma-Aldrich, C₂₅H₃₀ClN₃, 407.98 g mol^–1),
methylene blue (MB) (Sigma-Aldrich, C₁₆H₁₈ClN₃S.3H₂O, 373.9 g mol^–1), and rhodamine
B (Sigma-Aldrich, C₂₈H₃₁ClN₂O_3, 479.01 g mol^–1) were used as received
without any further purification.

Kanth P C., Trivedi M.U., Patel K., Misra N.M, & Pandey M.K. (2021). Cucurbituril-Functionalized Nanocomposite as a Promising Industrial Adsorbent for Rapid Cationic Dye Removal. ACS Omega, 6(4), 3024-3036.

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Synthesis and Characterization of Metal-Organic Complexes

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N-methyldi ethanolamine (NMDEA, >99%), diethylene glycol (DEG, >99%), iron(III) chloride hexahydrate (FeCl₃∙6H₂O, 99%), iron(II) chloride tetrahydrate (FeCl₂∙4H₂O, 99%), cobalt(II) chloride hexahydrate (CoCl₂∙6H₂O, 99%) and manganese(II) chloride tetrahydrate (MnCl₂∙4H₂O, 99%) are purchased from Merck (Darmstadt, Germany). Sodium hydroxide pellets (NaOH, 99%), hydrochloric acid (HCl, 37%), ethanol (96%), nitric acid (HNO₃, 68%), acetone (>99%), and diethyl ether (Et₂O, 100%) are purchased from VWR International (Rosny-sous-Bois, France). All chemicals are used without further purification.

Bertuit E., Neveu S, & Abou-Hassan A. (2021). High Temperature Continuous Flow Syntheses of Iron Oxide Nanoflowers Using the Polyol Route in a Multi-Parametric Millifluidic Device. Nanomaterials, 12(1), 119.

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Trace Metal Analysis in Anaerobic Media

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The amount of metal in fresh media (Anaerobic Basal Broth) was analyzed via Inductively Coupled Plasma Mass Spectroscopy by the Wisconsin State Lab of Hygiene.
In metal supplementation experiments, supernatants were supplemented with iron (II) sulfate (Alfa Aesar), manganese (II) sulfate monohydrate (Sigma-Aldrich), nickel sulfate (II) hexahydrate (Sigma-Aldrich), zinc (II) sulfate heptahydrate (Alfa Aesar), and/or cobalt (II) chloride hexahydrate (Sigma-Aldrich). Metal compounds were prepared as 100× stocks in water and filter sterilized with 0.2 μM filters.

Hromada S, & Venturelli O.S. (2023). Gut microbiota interspecies interactions shape the response of Clostridioides difficile to clinically relevant antibiotics. PLOS Biology, 21(5), e3002100.

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Synthesis of Metal Complexes

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The following chemicals were purchased from Sigma Aldrich and their purity is indicated in brackets: Anthranilic acid reagent grade (> 98%), Zinc chloride reagent grade (> 98%), Bismuth(III) nitrate pentahydrate ACS reagent(> 98.0%), Silver nitrate ACS reagent (> 99.0%), Iron(II) sulfate heptahydrate ACS reagent (> 99.0%), Cobalt(II) chloride hexahydrate(> 97%), Copper(II) sulfate pentahydrate ACS reagent(> 98.0%), Manganese(II) chloride tetrahydrate ACS reagent (> 98%), Aluminium sulfate octadecahydrate (> 98%), Zinc nitrate hexahydrate reagent grade (98%), Chromium(III) nitrate nonahydrate (99%). The chemicals were used without further purification.

Nawaz M., Abbasi M.W., Tariq M., Graham J.P., Al-Hagri A.R., Elkarim A.A., Mohamed M.E., Nissapatorn V., Taha M, & Hisaindee S. (2022). Synthesis of metal anthranilate complexes: catalytic and antipathogenic studies. BMC Chemistry, 16(1), 21.

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