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S cpt

Manufactured by Merck Group
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S-(+)-CPT is a chemical compound used in various laboratory applications. It serves as a core functional component in research and analytical processes. The detailed description and intended use of this product are not readily available at this time.

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Lab products found in correlation

Phosphate buffered saline ph 7.4, by Merck Group (1 mentions) Cholesterol, by Avanti Polar Lipids (1 mentions) Chloroform and methanol, by Merck Group (1 mentions) Flavone, by Merck Group (1 mentions) Acridine orange base, by Merck Group (1 mentions) Vegf a165, by R&D Systems (1 mentions) Acridine yellow g, by Merck Group (1 mentions) 9 aminoacridine, by Merck Group (1 mentions) Quercetin, by Merck Group (1 mentions)

2 protocols using s cpt

1

Encapsulation of Camptothecin in Liposomes

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The following materials were used in the study: camptothecin (CPT), S-(+)-CPT, approximately 95% by HPLC (Sigma Chemical Co., St. Louis, MO, USA), egg L-alpha-phosphatidylcholine ≥99% (L-alpha-lecithin), cholesterol ≥99% (Avanti Polar Lipids Inc., Alabaster, AL, USA), PEG (M.W. 2000 and 5000 Daltons; Sigma Chemical Co., St. Louis, MO, USA), chloroform and methanol (Merck and Co., Kenilworth, NJ, USA), phosphate-buffered saline (pH 7.4; Sigma Chemicals, St. Louis, MO, USA), dialysis tubing membrane (M.W. cut off 12,000–14,000 Daltons), and dialysis tubing closures (Sigma Aldrich, St. Louis, MO, USA). The chemicals used were of analytical grade.
Sivadasan D., Sultan M.H., Madkhali O.A., Alsabei S.H, & Alessa A.A. (2022). Stealth Liposomes (PEGylated) Containing an Anticancer Drug Camptothecin: In Vitro Characterization and In Vivo Pharmacokinetic and Tissue Distribution Study. Molecules, 27(3), 1086.
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2

Cellular Stimulation Protocols

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The following chemicals and concentrations were used for stimulation: human recombinant VEGF-A 165 (R&D Systems, 293-VE, 30 ng/mL), ACF (A8126, Sigma-Aldrich), acridine (A23609, Sigma-Aldrich), acridine orange base (235474, Sigma-Aldrich), acridine-9-carboxaldehyde (775525, Sigma-Aldrich), 9-aminoacridine (A7295, Sigma-Aldrich), (S)-(+)-CPT (C9911, Sigma-Aldrich), DOX (15,007, Cayman), flavone (F2003, Sigma-Aldrich), quercetin (PHR1488, Sigma-Aldrich), and acridine yellow G (199,508, Sigma-Aldrich).
Seredinski S., Boos F., Günther S., Oo J.A., Warwick T., Izquierdo Ponce J., Lillich F.F., Proschak E., Knapp S., Gilsbach R., Pflüger-Müller B., Brandes R.P, & Leisegang M.S. (2022). DNA topoisomerase inhibition with the HIF inhibitor acriflavine promotes transcription of lncRNAs in endothelial cells. Molecular Therapy. Nucleic Acids, 27, 1023-1035.
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