Total protein, urea, glucose, triacylglycerols and total cholesterol were determined by commercial Beckman Coulter enzymatic kits on a Beckman Coulter DxC 700 AU analyzer (Beckman Coulter, Brea, CA, USA). Cortisol concentrations were assessed with an Immulite 2000 cortisol assay on an IMMULITE 2000® autoanalyzer (DPC, Los Angeles, CA, USA). Finally, testosterone levels were determined using a commercial DIAsource TESTO-RIA-CT kit (DIAsource Immunoassays S.A., Louvain-la-Neuve, Belgium).
Dxc 700 au analyzer
Manufactured by Beckman Coulter
Sourced in United States
The DxC 700 AU analyzer is a fully automated clinical chemistry analyzer designed for high-volume clinical laboratories. It is capable of performing a wide range of clinical chemistry tests, including tests for metabolic disorders, kidney and liver function, and electrolyte imbalances. The DxC 700 AU analyzer features a high-throughput design and advanced analytical technologies to provide accurate and reliable results.
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Lab products found in correlation
4 protocols using dxc 700 au analyzer
1
Comprehensive Biochemical Analysis
2
Comparative Evaluation of HbA1c Assays
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HbA1c values of the 120 samples were measured using two immunoassay analyzers: Cobas c 513 analyzer (Roche Diagnostics) and DxC 700 AU analyzer (Beckman Coulter). Both devices use the turbidimetric inhibition immunoassay method with whole blood (treated with EDTA or heparin as an anti-coagulant) as the sample type. The Cobas c 513 analyzer was operated in batch mode with a throughput of 400 tests/hr. The DxC 700 AU analyzer was also operated in batch mode and random-access mode and could process up to 800 tests/hr. Cobas c 513 and DxC 700 AU are traceable to the National Glycohemoglobin Standardization Program (NGSP) and IFCC, respectively.
3
Routine Laboratory Biomarker Measurements
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Routine laboratory parameters were assessed using certified reagents and techniques with appropriate analytical properties in accredited clinical laboratories. Copeptin (CPP) serum concentration was determined using competitive ELISA principle by Human CPP (Copeptin) ELISA kit (Novus Biologicals, LLC, Centennial, CO, USA; Bio-Techne Ltd., Oxford, United Kingdom) on the automated ELISA analyzer Siemens BEP 2000 Advance (Siemens Healthcare Diagnostics Walpole, NJ, USA). Immunoglobulin A (IgA), G (IgG), and M (IgM), as well as complement component C3 (C3) and C4 (C4) serum concentrations were measured by immunoturbidimetric assay on Beckman Coulter DxC 700 AU analyzer (Beckman Coulter, Brea, CA, USA). DBC parameters (absolute number of neutrophilic granulocytes and lymphocytes) were determined using Abbott Cell Dyn Ruby (Abbott Diagnostics, Abbott Park, IL, USA) hematology analyzer in K2EDTA whole blood samples within 1 h after sampling. Neutrophil-to-lymphocyte ratio (NLR) was calculated by dividing the absolute number of neutrophils with the absolute number of lymphocytes.
4
Linezolid Pharmacokinetics during ECMO
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PK sampling was performed at a steady-state linezolid concentration during ECMO therapy. To ensure a steady-state concentration, at least six doses were administered before sampling. Blood was drawn into 6 mL clot activator tubes from an existing arterial or venous line at the following timepoints: pre-dose and 30, 60, 120, 240, and 360 min after the start of the infusion. The blood samples were centrifuged at 3000× g for 15 min, and the sera were kept frozen at −80 °C until analysis. Linezolid concentration was measured with the DxC 700 AU analyzer (Beckman Coulter Inc., Brea, CA, USA) using the homogeneous enzyme immunoassay kit ARK™ Linezolid Assay (ARK Diagnostics, Inc., Fremont, CA, USA) with measurement ranges from 0.75 to 30 μg/mL.
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