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Isoflurane o2

Manufactured by Baxter
Sourced in Germany

Isoflurane/O2 is a medical device used to administer a combination of isoflurane, a general anesthetic, and oxygen. It is designed to provide a controlled and precise delivery of these substances for use in medical procedures, such as general anesthesia.

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2 protocols using isoflurane o2

1

Partial Liver Ligation in Rats

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Rats were anesthetized via inhalation of isoflurane/O2 (Baxter International, Inc., Munich, Germany). Following a midline laparotomy, the liver was removed from the ligaments. A double running suture was performed on sham-operated rats. The selective PVL was performed on the middle and left lobes (lobes 1–3) under a microscope. Then, the middle and left lobes (lobes 1–3) were defined as ligated lobes, while the right lobes were defined as non-ligated lobes (lobes 4–7). The corresponding portal veins of the liver were ligated with a 7-0 Fumalen following careful dissection of the hepatic artery. Portography was performed prior to and following the selective PVL to visualize the liver anatomy and to demonstrate portal occlusion of the appropriate liver segments.
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2

Optic Nerve Crush Protocol

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Anaesthesia was induced with 5%/95% Isoflurane/O2 (Baxter Healthcare Corp, Deerfield, IL)/1.5L per minute and maintained at 3.5% throughout the procedure whilst analgesia was provided via an intraperitoneal injection of Buprenorphine (0.3 mg/kg). Intraorbital ONC was performed as previously described (Berry et al., 1996 (link)). Briefly, the optic nerve was surgically exposed under the superior orbital margin and crushed using fine forceps 1 mm posterior to the lamina cribrosa, taking care to separate the dura mater and under lying retinal artery before crushing.
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