Vinyl pyrrolidone

Manufactured by Merck Group

Sourced in United States

Vinyl pyrrolidone is a chemical compound used in various laboratory applications. It serves as a functional monomer for the production of polymers and copolymers. The core function of vinyl pyrrolidone is to act as a building block in the synthesis of specialized materials for research and industrial purposes.

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Lab products found in correlation

N hexane, by Merck Group (2 mentions) Sodium dodecyl sulfate (sds), by Merck Group (2 mentions) Dimethyl sulfoxide (dmso), by Merck Group (2 mentions) Maleic anhydride, by Merck Group (2 mentions) N isopropylacrylamide, by Merck Group (2 mentions) N n cystamine bisacrylamide, by Merck Group (2 mentions) Sodium acetate, by Merck Group (1 mentions) Iron 3 chloride hexahydrate, by Merck Group (1 mentions) Malonic acid, by Merck Group (1 mentions) Epigallocatechin gallate (egcg), by Tokyo Chemical Industry (1 mentions) Epicatechin gallate, by Tokyo Chemical Industry (1 mentions) Molybdenum disulfide, by Merck Group (1 mentions) Catechin, by Tokyo Chemical Industry (1 mentions) Epicatechin, by Tokyo Chemical Industry (1 mentions) Epigallocatechin, by Tokyo Chemical Industry (1 mentions) Ammonium persulfate, by Daejung Chemicals (1 mentions) Orthophosphoric acid, by Thermo Fisher Scientific (1 mentions) Sodium chloride (nacl), by Thermo Fisher Scientific (1 mentions) Hydrochloric acid (hcl), by Thermo Fisher Scientific (1 mentions) Methanol, by Thermo Fisher Scientific (1 mentions)

Spelling variants of this product

1-vinyl-2-pyrrolidone (12 citations) N-vinyl-2-pyrrolidone (7 citations) 1-vinyl-2-pyrrolidone (NVP), (4 citations) Poly(N-vinyl-2-pyrrolidone) (3 citations) Poly(N-vinyl-2-pyrrolidone) (PVP) (3 citations) 1-vinyl-2-pyrrolidone (VP) (3 citations) Poly(vinyl pyrrolidone) (PVP, Mw 40,000) (2 citations) N-vinyl-2-pyrrolidone (NVP) (2 citations)

4 protocols using vinyl pyrrolidone

Synthesis of Polyphenol-Functionalized Nanocomposite

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Vinyl pyrrolidone (VP), iron (III) chloride hexahydrate (FeCl₃·6H₂O), sodium acetate, malonic acid (MA), and molybdenum disulfide (MoS₂) were purchased from Sigma Chemical Co. (St. Louis, MO, USA). Acetic acid and ethylene glycol were procured from Duskan Pure Chemical (Kyungki-do, Korea). Methanol and ethanol were acquired from Fisher Scientific (Seoul, Korea). Ammonium persulfate (APS), 3-methacryloxypropyltrimethoxysilane (MPS), Ethylene glycol dimethacrylate (EGDMA), and 2-methylpropionitrile (AIBN) were purchased from Daejung Chemicals & Metals (Gyonggido, Korea). The standard chemicals of (+)-catechin (C, ≥98%), (−)-epicatechin (EC, ≥90%), (−)-epigallocatechin (EGC, ≥95%), (−)-epicatechin gallate (ECG, ≥95%), and (−)-epigallocatechin gallate (EGCG, ≥98%) were supplied by Tokyo Chemical Industry (Tokyo, Japan). All other solvents used in the experiment were either of HPLC or analytical grade.

Ma W, & Row K.H. (2020). Solid-Phase Extraction of Catechins from Green Tea with Deep Eutectic Solvent Immobilized Magnetic Molybdenum Disulfide Molecularly Imprinted Polymer. Molecules, 25(2), 280.

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Synthesis and Characterization of Lipid-Based Nanoparticles

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Sphingomyelin (SM) was purchased from Avanti Polar Lipid (Alabaster, AL). Ethylenediaminetetraacetic acid (EDTA), tris(hydroxymethyl)aminomethane (Tris), ammonium hydroxide, diethyl ether, toluene, dimethyl sulfoxide, n-hexane, benzene, N-isopropylacrylamide, vinyl pyrrolidone, sodium dodecylsulfate, sodium acrylate, N,N′-cystamine bisacrylamide (S-S, a disulfide crosslinker), ammonium persulfate, maleic anhydride and 5-aza-2′-deoxycytidine (decitabine; DAC), cholesterol (CHOL) were purchased from Sigma-Aldrich (St. Louis, MO). Doxorubicin hydrochloride was purchased from Drug Source Co. LLC (Westchester, IL). Poly(ethylene glycol) (M.W. ~5000) was purchased from Polysciences, Inc. (Warrington, PA). Hydrochloric acid, sodium chloride, isopropanol, petroleum ether, glacial (water-free) acetic acid, ethanolic phosphomolybdic acid, copper sulfate pentahydrate, 98% sulfuric acid, 85% orthophosphoric acid of reagent grade, and chloroform, methanol, and isopropanol of high-performance liquid chromatography grade were purchased from Fisher Scientific (Pittsburgh, PA).

Raghavan V., Vijayaraghavalu S., Peetla C., Yamada M., Morisada M, & Labhasetwar V. (2015). Sustained Epigenetic Drug Delivery Depletes Cholesterol-Sphingomyelin Rafts from Resistant Breast Cancer Cells, Influencing Biophysical Characteristics of Membrane Lipids. Langmuir : the ACS journal of surfaces and colloids, 31(42), 11564-11573.

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Synthesis of VP-APS Copolymer

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Vinyl pyrrolidone (VP) and mineral oil were purchased from Sigma-Aldrich Chemical Co. (St. Louis, MO, USA). Allyl phenyl sulfide (APS) was purchased from Tokyo Chemical Industry Co. Ltd., (Tokyo, Japan). 2,2’-Azobisisobutyronitrile (AIBN) was purchased from Junsei Chemical Co. (Tokyo, Japan). Tetrahydrofuran, hexane and H₂O₂ solution (30%) were purchased from Dae Jung Chemicals & Metals Co., Ltd. (Siheung, South Korea).

Park S.H, & Kim J.C. (2020). Oxidation–Responsive Emulsions Stabilized with Poly(Vinyl Pyrrolidone-co-allyl Phenyl Sulfide). Polymers, 12(2), 498.

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Hybrid Nanoparticle Platform for Targeted Cancer Therapy

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DAC (5-aza-2′-deoxycytidine; generic name decitabine) and SAHA (generic
name vorinostat), N-isopropylacrylamide (NIPAM), n-hexane, benzene, vinyl pyrrolidone
(VP), sodium dodecyl sulfate (SDS), N,N’-cystamine bis-acrylamide (an S-S
crosslinker), ammonium persulfate (APS), maleic anhydride, and dimethyl sulfoxide (DMSO)
were purchased from Sigma-Aldrich (St. Louis, MO). Poly(ethylene glycol) (PEG; MW
~5000) was purchased from Polysciences, Inc. (Warrington, PA). Doxorubicin HCl
(DOX) was purchased from Drug Source Co. LLC (subsidiary of Celgene Corp.; Westchester,
IL). Cell-culture media, Dulbecco’s phosphate-buffered saline (DPBS), penicillin,
and streptomycin were purchased from the Central Cell Services Media Laboratory at our
institution. The CellTiter 96® AQueous One Solution Cell Proliferation Assay (MTS)
was purchased from Promega (Madison, WI). All organic solvents used were of
high-performance liquid chromatography (HPLC) grade. HPLC columns and guard columns were
purchased from Waters Corp. (Milford, MA).

Vijayaraghavalu S, & Labhasetwar V. (2018). Nanogel-mediated delivery of a cocktail of epigenetic drugs plus doxorubicin overcomes drug resistance in breast cancer cells. Drug delivery and translational research, 8(5), 1289-1299.

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