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Skyra 3 tesla

Manufactured by Siemens
Sourced in Germany

The Skyra 3 Tesla is a magnetic resonance imaging (MRI) system developed by Siemens. It operates at a magnetic field strength of 3 Tesla, which is a standard for high-quality MRI imaging. The Skyra 3 Tesla is designed to capture detailed images of the human body for diagnostic and research purposes.

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7 protocols using skyra 3 tesla

1

Neuroimaging of Food Cue Reactivity

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Structural, as well as functional MRI of the brain, were measured in a part of the study population (n  = 19 completed with additional three drop-outs during the fMRI) as well as in a healthy, lean control group (n  = 22). Data were obtained using a Siemens Skyra 3 Tesla whole-body scanner (Siemens Medical Systems, Erlangen, Germany). After a 5-min resting-state measurement, a structural image as well as functional measurements during a task, in which high- and low-caloric and non-food pictures were presented (51 (link)), were measured. Additionally, diffusion tensor imaging was applied.
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2

3T MRI Neuroimaging Protocol for Brain Analyses

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Neuroimaging was performed on a Siemens Magnetom Skyra 3 Tesla MRI scanner using a 32 channel head coil (Siemens Medical Imaging, Erlangen, Germany). A 3D T1‐weighted MPRAGE sequence was acquired in the sagittal orientation (TI 900 ms, TR 1540 ms, TE 2.57 ms, resolution 256 × 256 × 176, flip angle 9°, FOV 250 mm, slice thickness 1.00 mm [176 slices]). A DTI sequence was acquired (TR = 10,900, TE = 101,64 diffusion encoding directions, number of excitations = 1, slice thickness = 2.0 mm (64 slices), field of view = 256 mm, matrix = 128 × 128, in‐plane = 2.0 × 2,0 mm, b value = 2,000 s/mm2).
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3

Epilepsy-Protocol MRI Data Collection

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We retrospectively collected epilepsy-protocol MRI data, including three-dimensional (3D) T1-weighted images, that were obtained from patients with epilepsy or with suspected seizures. Between 2009 (when epilepsy-protocol MRI scans were introduced) and 2020, 1,375 3D T1-weighted MRI examinations were performed with 8 different scanners. To develop a standard reference for the MAP specific to our center, MRIs by two frequently used scanners (Philips Ingenia CX 3-tesla and Siemens Skyra 3-tesla; www.usa.philips.com/healthcare/solutions/magnetic-resonance, https://www.siemens-healthineers.com/magnetic-resonance-imaging) were chosen among 965 normal-looking MRI scans, and 3D T1-weighted images from each scanner served as the inputs for the MAP analysis (Fig. 1).11 (link) The Ingenia group consisted of 101 patients (mean age of 34 years, age range of 16–69 years; including 58 males), while the Skyra group consisted of 93 patients (median age of 35 years, age range of 16–65 years; including 45 males). The normal reference of our institution comprising two scanners was incorporated into the MAP, which was kindly provided by the developer (Professor Hans-Jürgen Huppertz).
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4

Multiparametric MRI Evaluation Protocol

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The study protocols were performed by using Siemens Magnetom Skyra 3 Tesla MRI machine with; coronal, sagittal and axial sections, T1WI, T2WI, STIR sequences, DCE-MRI, DWI sequences, and ADC. On the other hand, DWI and ADC maps were observed on axial plane with b value 800 s/mm2. Formerly, contrast injection was performed using SS-EPI technique with the following parameters: TR (4430-6640 ms), TE (55-76 ms), FOV 200-325 mm2, matrix size (voxel) 115x128, 5-6 mm thickness with 1.5 mm interslice gap, and average of 1-2. Furthermore, DCE MR imaging was performed in the coronal or sagittal plane (time-resolved angiography with interleaved stochastic trajectories: 2.2-4.16/0.77-1.33; field of view, 230-400 mm; matrix, 108-256 pixels; section thickness, 3-8 mm, (based on the anatomic body part), capturing arterial, mixed, and venous phase images. The sequence was started simultaneously with an intravenous bolus administration of 0.1 mmol/kg bwt. Gadolinium-DTPA injected at a rate of 3 mL/sec and images from 30 phases were acquired within a minimum temporal resolution of time as in seven second. Moreover, a composite set of images was reconstructed with maximum intensity projection in coronal, axial, and sagittal planes. The enhancement in the volume of interest could be viewed throughout different phases.
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5

Multimodal MRI Brain Imaging Protocol

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Each MRI study includes the following images, all collected on a Siemens Skyra 3 Tesla (3T) scanner: a T1 map, acquired as two T1-FLASH (Fast Low Angle SHot) sequences at differing flip angles [TR=7.8ms, TE=3ms, FA=3/18] (Christensen et al., 1974 ; Gupta, 1977 ) with a B0+B1 field map for FA correction (Duan et al., 2013 (link)); a T1w-MPRAGE (Magnetization-Prepared RApid Gradient Echo) image [TR=3000ms, TE=3.03ms, TI=900ms, FA=9]; PDw and T2w images from a dual-echo turbo spin echo (TSE) sequence [TR=3000ms, TE=11ms/101ms, FA=150, ETL=14]; and a 3D T2-weighted FLAIR image acquired using a T2-selective inversion pulse optimized for T2 of 120ms [TR=4800ms, TE=354ms, TI=1800ms, Variable FA]. All scans were acquired at 1.0mm isotropic resolution except the PDw/T2w TSE sequence, which was acquired at 0.93 × 0.93 × 3.0mm resolution.
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6

Resting-State fMRI from the Human Connectome Project

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We used data from a public repository, the 1200 subjects release of the Human Connectome Project (HCP) (Van Essen et al., 2013 (link)). The HCP provides MRI data and extensive behavioral assessment from almost 1200 subjects. Acquisition parameters and “minimal” preprocessing of the resting-state fMRI data is described in the original publication (Glasser et al., 2013 (link)). Briefly, each subject underwent two sessions of resting-state fMRI on separate days, each session with two separate 15 minute acquisitions generating 1200 volumes (customized Siemens Skyra 3 Tesla MRI scanner, TR = 720 ms, TE = 33 ms, flip angle= 52°, voxel size = 2 mm isotropic, 72 slices, matrix = 104 × 90, FOV = 208 mm × 180 mm, multiband acceleration factor = 8). The two runs acquired on the same day differed in the phase encoding direction, left-right and right-left (which leads to differential signal intensity especially in ventral temporal and frontal structures). The HCP data was downloaded in its minimally preprocessed form, i.e. after motion correction, B0 distortion correction, coregistration to T1-weighted images and normalization to MNI space (the T1w image is registered to MNI space with a FLIRT 12 DOF affine and then a FNIRT nonlinear registration, producing the final nonlinear volume transformation from the subject’s native volume space to MNI space).
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7

In Vivo 31P MRS of Healthy Brain

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Ten in vivo 31P MRS datasets, which were acquired from five healthy participants (mean age 26.8 ± standard deviation 7.7 years) at 3 Tesla and five healthy participants (age 33.5 ± 10.3 years) at 7 Tesla [11 (link)], were analyzed in this study. The data acquisition procedures have been described previously [11 (link)]. Briefly, MRS measurements were performed on Siemens Skyra 3 Tesla and Magnetom 7 Tesla scanners (Siemens Healthcare, Erlangen, Germany) using home-built coil assemblies composed of a circular 31P coil with a 7.0 cm diameter and a quadrature half-volume 1H coil. In vivo 31P MRS spectra were acquired without 1H decoupling. Acquisition parameters at 3 Tesla were as follows: TR = 2 s; spectral width = 5 kHz; number of acquisitions = 128; number of data points = 1024. Identical parameters were used for 7 Tesla data acquisition, except that TR = 3 s.
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