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Sterile normal saline solution

Manufactured by Merck Group
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Sterile normal saline solution is a sterile, isotonic saline solution that is commonly used in various laboratory and medical applications. It is a solution of sodium chloride in purified water, with a concentration of 0.9 grams of sodium chloride per 100 milliliters of solution. This solution mimics the osmotic pressure and ionic concentration of the human body, making it suitable for maintaining the appropriate physiological balance in various laboratory experiments and procedures.

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Lab products found in correlation

Bleomycin, by Merck Group (2 mentions) Trichostatin a, by Merck Group (1 mentions) Nintedanib, by Boehringer Ingelheim (1 mentions)

2 protocols using sterile normal saline solution

1

Bleomycin-Induced Lung Injury Model

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HDAC inhibitor (trichostatin A, Sigma, St. Louis, MO) 2 mg/kg was given intraperitoneally 1 h before ventilation based on our present and previous studies that showed 2 mg/kg inhibited HDAC activity [19 (link)]. The mice received a single dosage of 0.075 units of bleomycin in 100 μL of sterile normal saline solution intratracheally (Sigma, St. Louis, MO) and were ventilated 5 days after the administration of bleomycin [8 (link)].
Li L.F., Lee C.S., Lin C.W., Chen N.H., Chuang L.P., Hung C.Y, & Liu Y.Y. (2017). Trichostatin A attenuates ventilation-augmented epithelial-mesenchymal transition in mice with bleomycin-induced acute lung injury by suppressing the Akt pathway. PLoS ONE, 12(2), e0172571.
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2

Nintedanib Attenuates Bleomycin-Induced Lung Injury

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Nintedanib was administered once daily through gavage at 30, 60 and 100 mg/kg for 5 days before MV (Boehringer Ingelheim, Biberach, Germany) 21. The mice received a single dosage of 0.075 units of bleomycin in 100 μl of sterile normal saline solution intratracheally (Sigma‐Aldrich, St. Louis, MO, USA) and were ventilated 5 days after the administration of bleomycin 13.
Li L., Kao K., Liu Y., Lin C., Chen N., Lee C., Wang C, & Yang C. (2017). Nintedanib reduces ventilation‐augmented bleomycin‐induced epithelial–mesenchymal transition and lung fibrosis through suppression of the Src pathway. Journal of Cellular and Molecular Medicine, 21(11), 2937-2949.
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