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Glycolithocholic acid

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Glycolithocholic acid is a bile acid found in the human body. It is used as a reference standard and analytical reagent in biochemical and clinical research applications.

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Lab products found in correlation

Formic acid, by Thermo Fisher Scientific (9 mentions) Acetonitrile, by Thermo Fisher Scientific (5 mentions) Glycodeoxycholic acid, by LGC (4 mentions) Sodium glycochenodeoxycholate, by Merck Group (3 mentions) Taurocholic acid sodium salt hydrate, by Merck Group (3 mentions) Ammonium formate, by Thermo Fisher Scientific (3 mentions) Sodium taurodeoxycholate hydrate, by Merck Group (3 mentions) Chenodeoxycholic acid, by Merck Group (3 mentions) Cholic acid, by Merck Group (3 mentions) 2 propanol, by Thermo Fisher Scientific (3 mentions) Methanol, by Thermo Fisher Scientific (3 mentions) Lithocholic acid, by Cayman Chemical (2 mentions) Hyodeoxycholic acid, by Merck Group (2 mentions) Sodium taurochenodeoxycholate glycocholic acid hydrate, by Merck Group (2 mentions) Sodium taurolithocholic acid, by Merck Group (2 mentions) Sodium taurohyodeoxycholate hydrate, by Merck Group (2 mentions) Ursodeoxycholic acid, by Santa Cruz Biotechnology (2 mentions) Deoxycholic acid, by Santa Cruz Biotechnology (2 mentions) Glycodeoxycholic acid sodium salt, by Merck Group (2 mentions) 7 ketodeoxycholate, by LGC (2 mentions)

4 protocols using glycolithocholic acid

1

Comprehensive Bile Acid Analytical Protocol

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Cholic acid (CA), chenodeoxyCholic acid (CDCA), sodium glycochenodeoxycholate (GCDCA), sodium taurochenodeoxycholate (TCDCA), glycoCholic acid (GCA), taurolithoCholic acid (TLCA), sodium taurodeoxycholate hydrate (TDCA), and tauroCholic acid sodium salt hydrate (TCA) were purchased from Sigma-Aldrich (Saint Louis, MI). UrsodeoxyCholic acid (UDCA) and deoxyCholic acid (DCA) were purchased from ChemCruz (Santa Cruz Biotechnology, Inc., Dallas TX). LithoCholic acid (LCA) and glycoursodeoxyCholic acid (GUDCA) were purchased from Cayman Chemical Company, (Michigan, USA). GlycodeoxyCholic acid (GDCA) and glycolithoCholic acid (GLCA) were purchased from Toronto Research Chemicals (TRC, Canada). Formic acid (99 + %) was purchased in 1 mL ampules from Thermo Scientific (Rockford, IL, USA). Ammonium formate and 2-propanol (both Optima® LC/MS grade), acetonitrile, methanol and water (both Optima® grade) were purchased from Fisher Chemical (Fair Lawn, NJ, USA).
Cai Y., Shen X., Lu L., Yan H., Huang H., Gaule P., Muca E., Theriot C.M., Rattray Z., Rattray N.J., Lu J., Ahuja N., Zhang Y., Paty P.B., Khan S.A, & Johnson C.H. (2022). Bile acid distributions, sex-specificity, and prognosis in colorectal cancer. Biology of Sex Differences, 13, 61.
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2

Bile Acid Standards for Analytical Methods

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Cholic acid, chenodeoxyCholic acid, hyodeoxyCholic acid, sodium glycochenodeoxycholate, sodium taurochenodeoxycholate glycoCholic acid hydrate, sodium taurolithoCholic acid, sodium taurodeoxycholate hydrate, sodium taurohyodeoxycholate hydrate, and tauroCholic acid sodium salt hydrate were purchased from Sigma-Aldrich (Saint Louis, MI, USA). GlycodeoxyCholic acid sodium salt (EMD, Millipore Corp., Burlington, MA, USA), ursodeoxyCholic acid, deoxyCholic acid (Chem-Cruz, Santa Cruz Biotechnology Inc., Dallas TX, USA), lithoCholic acid (Cayman Chemical Company, Ann Arbor, MI, USA), and glycodeoxyCholic acid, glycolithoCholic acid, glycodeoxyCholic acid, 7-ketodeoxycholate and 7-ketolithoCholic acid were purchased from Toronto Research Chemicals (North York, ON, Canada). Formic acid (99+%) was purchased in 1 mL ampoules from Thermo Scientific (Rockford, IL). Ammonium formate and 2-propanol (both Optima® LC/MS grade), acetonitrile and water (both Optima® grade) were purchased from Fisher Chemical (Fair Lawn, NJ, USA).
Charkoftaki G., Tan W.Y., Berrios-Carcamo P., Orlicky D.J., Golla J.P., Garcia-Milian R., Aalizadeh R., Thomaidis N.S., Thompson D.C, & Vasiliou V. (2022). Liver metabolomics identifies bile acid profile changes at early stages of alcoholic liver disease in mice. Chemico-biological interactions, 360, 109931.
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3

Comprehensive Bile Acid Analysis by LC-MS

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LC-MS grade water, methanol and acetonitrile were purchased from Thermo Fisher Scientific (Sydney, Australia). Chenodeoxycholic acid (2,2,4,4-d4) (CDCA-d4), cholic acid (CA), chenodeoxycholic acid (CDCA), deoxycholic acid (DCA), lithocholic acid (LCA), ursodeoxycholic acid (UDCA), glycodeoxycholic acid (GDCA), glycocholic acid (GCA), glycolithocholic acid (GLCA), taurochenodeoxycholic acid (TCDCA), taurocholic acid (TCA), taurodeoxycholic acid (TDCA), tauroursodeoxycholic acid (TUDCA) were purchased from Toronto Research Chemicals (Toronto, Canada). lithocholic acid (2,2,4,4-d4) (LCA-d4) and taurodeoxycholic acid (2,2,4,4-d4) (TDCA-d4) were obtained from Cambridge Isotope Laboratories, Inc. (Massachusetts, USA). deoxycholic acid (2,2,4,4-d4) (DCA-d4) was purchased from Sigma-Aldrich (NSW, Australia).
Shafaei A., Rees J., Christophersen C.T., Devine A., Broadhurst D, & Boyce M.C. (2021). Extraction and quantitative determination of bile acids in feces. Analytica chimica acta, 1150.
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4

Comprehensive Bile Acid Procurement and Standardization

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Cholic acid, chenodeoxyCholic acid, hyodeoxyCholic acid, sodium glycochenodeoxycholate, sodium taurochenodeoxycholate glycoCholic acid hydrate, sodium taurolithoCholic acid, sodium taurodeoxycholate hydrate, sodium taurohyodeoxycholate hydrate, and tauroCholic acid sodium salt hydrate were purchased from Sigma-Aldrich (Saint Louis, MI, USA). GlycodeoxyCholic acid sodium salt (EMD, Millipore Corp., Burlington, MA, USA), ursodeoxyCholic acid, deoxyCholic acid (ChemCruz, Santa Cruz Biotechnology Inc., Dallas TX, USA), lithoCholic acid (Cayman Chemical Company, Ann Arbor, MI, USA), and glycodeoxyCholic acid, glycolithoCholic acid, glycodeoxyCholic acid, 7-ketodeoxycholate and 7-ketolithoCholic acid were purchased from Toronto Research Chemicals (North York, ON, Canada). Formic acid (99+%) was purchased in 1 mL ampules from Thermo Scientific (Rockford, IL). Ammonium formate and 2-propanol (both Optima ® LC/MS grade), acetonitrile and water (both Optima ® grade) were purchased from Fisher Chemical (Fair Lawn, NJ, USA).
Charkoftaki G., Golla J.P., Santos‐Neto Á.J., Orlicky D.J., García-Milian R., Chen Y., Rattray N.J.W., Cai Y., Wang Y., Shern C.T., Mironova V., Wang Y., Johnson C.H., Thompson D.C., & Vasiliou V. (2020). Novel insights into the mode of action of 1,4-dioxane using a systems screening approach.
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