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Female wild type mice

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Female wild-type mice are a common laboratory animal model used for a variety of research purposes. These mice are genetically unmodified and exhibit normal, or 'wild-type', characteristics.

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Wild-type (WT) mice (4 citations) Female BALB/c wild type mice (3 citations) Wild-type C57BL/6 J female mice (2 citations) Female C57BL/6J wild type mice (2 citations)

3 protocols using female wild type mice

1

Transgenic Mouse Model for Prox1 Expression

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Female wild-type mice (Janvier) and Prox1-GFP reporter mice on the C57BL/6J background were kept under specific pathogen–free conditions and used for experimental studies at the age of 2–3 mo. Prox1-GFP mice were backcrossed to a C57BL/6J background for ≥10 generations. All mouse experiments were approved by the Kantonales Veterinäramt Zürich (license numbers 185/13, 161/16, and 245/17) and by the Landesamt für Gesundheit und Verbraucherschutz, Saarbruecken, Germany (license number 31/2018), and performed following the regulations of the Swiss Federal Welfare Act.
Ma Q., Decker Y., Müller A., Ineichen B.V, & Proulx S.T. (2019). Clearance of cerebrospinal fluid from the sacral spine through lymphatic vessels. The Journal of Experimental Medicine, 216(11), 2492-2502.
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2

Experimental studies using wild-type and Prox1-GFP mice

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Female wild-type mice (Janvier Labs) and Prox1-GFP reporter mice46 (link) on the C57BL/6 J background were kept under specific pathogen-free conditions and used for experimental studies at the age of 2 to 3 months.
Ma Q., Schlegel F., Bachmann S.B., Schneider H., Decker Y., Rudin M., Weller M., Proulx S.T, & Detmar M. (2019). Lymphatic outflow of cerebrospinal fluid is reduced in glioma. Scientific Reports, 9, 14815.
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3

Pathogen-Free Mouse Model Protocol

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Female wild-type mice (Janvier) on a C57BL/6 background were kept under specific pathogen–free conditions until they were used for experimental studies.
Decker Y., Krämer J., Xin L., Müller A., Scheller A., Fassbender K, & Proulx S.T. (2022). Magnetic resonance imaging of cerebrospinal fluid outflow after low-rate lateral ventricle infusion in mice. JCI Insight, 7(3), e150881.
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