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Palbociclib plb

Manufactured by Selleck Chemicals

Palbociclib (PLB) is a chemical compound used in laboratory research. It is a cyclin-dependent kinase (CDK) 4 and 6 inhibitor, which plays a role in cell cycle regulation. Palbociclib can be used as a tool to study cell proliferation and its underlying mechanisms.

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2 protocols using palbociclib plb

1

Evaluating Cell Viability and Proliferation

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dTAG-13 was purchased from Tocris Bioscience. Doxycycline, hydroxyurea and CFSE (carboxyfluorescein diacetate N-succinimidyl ester) were from Sigma. Palbociclib (PLB) and AZ-20 were from Selleck Chemicals. EdU (5-ethynyl-2’-deoxyuridine) was from Invitrogen. Formaldehyde and paraFormaldehyde were obtained from Sigma and Electron Microscopy Sciences, respectively. DAPI (4′,6-diamidino-2-phenylindole) was from Thermo Fisher Scientific. All other chemical reagents were from Sigma.
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2

Cellular Labeling and Proliferation Assay

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dTAG-13 was purchased from Tocris Bioscience. Doxycycline, hydroxyurea, and CFSE (carboxyfluorescein diacetate N-succinimidyl ester) were from Sigma. Palbociclib (PLB) and AZ-20 were from Selleck Chemicals. EdU (5-ethynyl-2′-deoxyuridine) was from Invitrogen. Formaldehyde and paraFormaldehyde were obtained from Sigma and Electron Microscopy Sciences, respectively. DAPI (4′,6-diamidino-2-phenylindole) was from Thermo Fisher Scientific. All other chemical reagents were from Sigma.
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