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286 protocols using brilliance ict

1

Abdominal CT Imaging Protocol for Surgical Resection

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Prior to surgical resection, abdominal enhanced CT examinations of all enrolled patients
were performed, using one of the following CT equipment: Siemens Somatom Definition Flash
(Siemens Medical Solutions); Philips Brilliance iCT (Philips Medical Systems); Philips
Brilliance 64 (Philips Medical Systems); GE Discovery CT750 (GE Healthcare); and GE
LightSpeed VCT (GE Healthcare). The other acquisition parameters were as follows: 120 kV
tube voltage, 150–350 mAs tube current, 0.5–0.8 seconds tube rotation time,
64 × 0.625 mm detector collimation, 350 × 350 mm field of view, 512 ×
512 matrix, 1 mm section thickness, and 1 mm reconstruction interval. Prior to CT
examinations, the patients were required to fast for at least for six hours. For CT
examinations, 80 mL to 100 mL of iodinated contrast medium was injected intravenously at a
rate of 3.0 mL/s. The portal venous phase images (obtained 60 seconds after injection of
the contrast agent) were selected for this study.
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2

Contrast-Enhanced CT Imaging Protocol

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CE-CT images were obtained using one of three scanners as part of the participant’s clinical care. The scanners were either a Philips Big Bore, Philips Brilliance 64, or Philips Brilliance iCT (Philips Healthcare, Best, the Netherlands). Slice thicknesses for each scan ranged from 2.0 to 5.0 mm. Omnipaque contrast agent (GE Healthcare, Chicago, Illinois) was used at a dose of 100 mL administered at a rate of 4 mL/s.
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3

Contrast-Enhanced CT Imaging Protocol

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Contrast‐enhanced CT examinations were performed using one of the following MDCT scanners: Siemens Somatom Sensation 64 (Siemens, Forchheim, Germany); Philips Brilliance iCT, or Philips Brilliance 64 (Philips Medical Systems, Cleveland, OH, USA); GE LightSpeed VCT (GE Healthcare, Princeton, NJ, USA). The patients were fasted for at least 8 hours before examination. CT images were obtained during breath holding with the following parameters: 120 kV, 250 mA. The section thickness and reconstruction interval were 5.0 mm. An 80‐100 mL dose of nonionic intravenous contrast material was administered with a power injector at a rate of 3.0 mL/s. Then, at 28 and 60 seconds after injection with the agent, contrast‐enhanced scans in the arterial phase and portal venous phase were done. The CT scans were sent to a picture archiving and communication system (PACS) to be interpreted at workstations.
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4

Coronary Computed Tomography Angiography Protocol

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All patients underwent CCTA using a 256-slice CT scanner (Philips Brilliance iCT, Philips Healthcare, Best, the Netherlands) as previously described14 (link). The CCTA protocol is detailed in the Supplemental Methods. CCTA datasets were transmitted to an independent and blinded core laboratory (St. Paul’s Hospital, Vancouver, British Columbia, Canada) for the assessment of diameter stenosis severity. All coronary segments ≥2 mm in diameter15 (link) were visually graded and classified as: 0, 1–24, 25–49, 50–69, or 70–100%. Coronary lesions were also assessed for qualitative adverse plaque characteristics including positive remodeling (defined as remodeling index ≥1.1), low-attenuation plaque (containing any voxel <30 Hounsfield units [HU]), spotty calcification (<90° of vessel circumference and <3 mm in length)16 (link), and the napkin-ring sign17 (link).
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5

Radiological Evaluation of Radioembolization

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A radiological follow-up was performed to evaluate the radiological outcome of the treatment. The radiological follow-up consisted of a CT scan of the abdomen with i.v. contrast at 6 and 9 months after radioembolization. The follow-up CT scans were performed on a 256-slice CT (PHILIPS Brilliance ICT, Philips Medical Systems, Cleveland, OH, USA) and all images were reconstructed with a slice thickness of 2.5 mm.
All patients enrolled have been evaluated by a radiologist with more than 10 years of experience in abdominal CT scans. The radiological outcome was assessed using modified Response Evaluation Criteria in Solid Tumors (mRECIST) [14 (link)], which was evaluated 6 and 9 months after therapy.
The radiological follow-up was performed on 11 patients. Two patients treated did not join the follow-up for reasons unrelated to liver disease (Table 1).
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6

Optimized CT Urography Protocol

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All enrolled patients underwent CTU within 1–2 weeks prior surgery. Before the scan, patients were instructed to drink between 800 and 1000 ml of water, but not to urinate until the scan was over. After scanning, 50 mL of ioversol or 100 mL of iopamidol were intravenously administered, followed by 50 mL of saline at a rate of 3 mL/s. Images of the renal corticomedullary, nephrographic, and excretory phase were obtained at 25 s, 75 s, and 300 s after the thresholding of the thoracoabdominal aortic junction was reached. Subsequent analyses used only axial nephrographic phase images. Multidetector CT scanners with 64 to 128 detector rows (Siemens Healthineers, Philips Brilliance, and Philips Brilliance iCT) were used to obtain CT images. The scanning parameters were 120 kV, automatic mA settings (range 80–320 mA), layer spacing of 1 mm, and layer thickness of 1.5–3 mm. Soft tissue algorithm (window width (WW): 300–500 HU, window level (WL): 45–60 HU) were used after imaging.
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7

Multi-modal Chest CT Imaging Protocol

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Chest CT scans were performed with three multi-detector CT scanners (GE Optima 520 Pro, America; Philips Brilliance iCT, Netherlands; KAIPU CT precision 32, China). Each patient was scanned from the lung apex to the diaphragm during a breath-hold at end full inspiration and at end normal-expiration. CT acquisition was executed as follows: (a) GE Optima 520 Pro and Philips Brilliance iCT, tube voltage, 120 kVp; tube current, 250 mA; slice thickness, 1.25 mm; slice spacing, 1.25 mm; (b) KAIPU CT precision 32, tube voltage, 120 kVp; tube current, automatic mA; slice thickness, 1.25 mm; slice spacing, 0.7 mm. No contrast agent was administered.
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8

Coronary CT Angiography Protocol

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All patients underwent CCTA using a 256-slice CT scanner (Philips Brilliance iCT, Philips Healthcare, Best, the Netherlands). CCTA acquisition parameters were as follows: collimation 128 × 0.625 mm, gantry rotation 270ms, tube current 200-360 mA (according to body mass index), and tube voltage 120 kV. Prior to scanning, sublingual nitroglycerine was administered to all patients and metoprolol as required, aiming for a heart rate less than 65 beats/min. An intravenous bolus of 100ml of iodinated contrast was injected at 5.7 ml/s. The scan was triggered using an automatic bolus-tracking technique with a region of interest placed in the descending thoracic aorta. Prospective electrocardiogram gating was performed at 75% of the R-R interval.
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9

Computed Tomography Portal Venography

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All patients underwent CTPV with the absence of active bleeding for more than 48 hours after hospitalization. Before the examination, the patients fasted for 8–12 hours and practiced breathing exercises. Patients with tachycardia greater than 100 beats/min were given propranolol hydrochloride.
CTPV was performed using a 256-detector row CT scanner (Philips Brilliance iCT, Philips Healthcare, Best, The Netherlands) in three phases. Before the examination, 80 mL of iohexol (Omnipaque 350; Nycomed Amersham, Princeton, NJ) was administered intravenously as a contrast medium via a hand vein at 3.5 mL/s using a high-pressure injector. Images were obtained during the portal phase from the dome of the diaphragm to the iliac wing approximately 50–60 s after contrast injection, with the following parameters: section collimation, 0.625 mm; section thickness, 5 mm; pitch, 0.9; rotation time, 0.5 s per rotation; 120 kV; 343 mA. Three-dimensional CTPV images were reconstructed at an interval of 1.0 mm using the Philips EBW 4.5 workstation. Both maximum intensity projection and volume rendering were used for image reconstruction.
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10

CT Imaging Protocol for Chest Evaluation

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Non-contrast CT was performed with the patient in a supine position, and sections were taken from lung apices to the domes of diaphragm using a dual-source CT 128 slice scanner – Somatom Definition Flash (Siemens Healthcare, Forchheim, Germany)/third-generation 16 slice scanner, CT sensation 16 (Siemens Healthcare, Forchheim, Germany)/CT 256 Slice scanner, Philips Brilliance iCT (Philips Healthcare Best, The Netherlands). A helical dataset of the chest was acquired with 10 mm thick sections at 10 mm increment with automatic exposure control. HRCT images were reconstructed from the helical dataset into 1 mm sections at 1 mm increment (reconstruction kernel: B 80f ultrasharp filter for lung window and B 30f medium smooth for mediastinal window) using filter back projection.
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