3.0t trio scanner

Manufactured by Siemens

Sourced in Germany

The 3.0T Trio scanner is a magnetic resonance imaging (MRI) system produced by Siemens. It operates at a magnetic field strength of 3.0 Tesla and is designed to capture high-quality images of the human body for diagnostic and research purposes.

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Lab products found in correlation

12 channel phased array head coil, by Siemens (1 mentions) 3.0 t achieva mri scanner, by Philips (1 mentions) 8 channel sense head coil, by Philips (1 mentions) 12 channel head coil, by Siemens (1 mentions) E prime software 2, by Psychology Software Tools (1 mentions) Standard head coil, by Siemens (1 mentions) Eight channel coil, by Siemens (1 mentions) 8 channel head coil, by Siemens (1 mentions) 32 channel head coil, by Siemens (1 mentions)

16 protocols using 3.0t trio scanner

Diffusion MRI Acquisition in ALS and 4R-Tau Patients

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Diffusion-weighted MRIs were available for 10 ALS patients (1 with ALS-FTD) from a SIEMENS 3.0T Trio scanner using an 8-channel coil. Diffusion-weighted images (DWI) were acquired with a 30-directional sequence involving single-shot, spin-echo, diffusion-weighted echo planar imaging (FOV=245mm; matrix size=128×128; number of slices=57; voxel size=2.2mm isotropic; TR=6700msec; TE=85msec; fat saturation). We acquired 30 volumes with diffusion weighting (b=1000 s/mm2) along 30 non-collinear directions per subject, and either one (n=2) or four (n=17) without diffusion weighting (b=0 s/mm2). When four volumes were collected without diffusion weighting, these volumes were averaged to increase signal-to-noise ratio. Reasons for exclusion included health and safety (e.g., difficulty breathing while supine, metallic implants, shrapnel, claustrophobia) and lack of interest in an imaging study. DWI were also available for 9 4R-tau patients. T1-weighted MRI volumes were also acquired in the same scanning session with MPRAGE acquisition parameters: repetition time=1620msec; echo time=3msec; slice thickness=0.9mm; flip angle=15°; matrix=192×256, and in-plane resolution=0.9×0.9mm.

Grossman M., Elman L., McCluskey L., McMillan C.T., Boller A., Powers J., Rascovsky K., Hu W., Shaw L., Irwin D.J., Lee V.M, & Trojanowski J.Q. (2014). PHOSPHORYLATED TAU: CANDIDATE BIOMARKER FOR AMYOTROPHIC LATERAL SCLEROSIS. JAMA neurology, 71(4), 442-448.

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Structural and Diffusion MRI in bvFTD

Cited 1 time

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Structural T1-weighted MRI data were available for all bvFTD participants with PACT scores (n = 18), and diffusion tensor imaging (DTI) data from the same scan session were available for a subset of participants (n = 15). High-resolution T1-weighted 3-dimensional spoiled gradient echo images were acquired on a Siemens 3.0T Trio scanner with an 8-channel coil (repetition time = 1620 ms, echo time = 3 ms, slice thickness = 1.0 mm, flip angle = 15°, matrix = 192 × 256, and in-plane resolution = 0.9 × 0.9 mm). Diffusion-weighted images (DWI) were acquired using a single-shot, spin-echo, diffusion-weighted echo planar imaging sequence (FOV = 245 mm; matrix size = 128 × 128; number of slices = 57; voxel size = 2.2 mm isotropic; TR = 6700 ms; TE = 85 ms; fat saturation). In total, 31 volumes were acquired per subject, one without diffusion weighting (b = 0 s/mm²) and 30 with diffusion weighting (b = 1000 s/mm²) along 30 non-collinear directions. We selected a sample of 24 demographically-matched imaging controls from our control panel with existing MRI and DTI data for neuroanatomical comparison as previously reported (Healey et al., 2015 (link)). Two sample t-tests confirmed that imaging controls [mean age = 60.71 years (SD = 6.9); mean education = 15.79 years (SD = 1.9)] are demographically comparable to patients (age, education, and gender, all p > 0.1).

Massimo L., Powers J.P., Evans L.K., McMillan C.T., Rascovsky K., Eslinger P., Ersek M., Irwin D.J, & Grossman M. (2015). Apathy in Frontotemporal Degeneration: Neuroanatomical Evidence of Impaired Goal-directed Behavior. Frontiers in Human Neuroscience, 9, 611.

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3T MRI Brain Imaging Protocol

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For the study, MRI scans were conducted using a Siemens 3.0T Trio scanner (Siemens, Munich, Germany). During the MRI scanning, foam pads were placed on two sides of the heads of the subjects to restrict head motion, and cotton earplugs were used to reduce noise and protect the hearing of the subjects. Every subject was requested to stay awake with eyes closed and not to think specific thoughts during the MRI scan. T1-weighted images were obtained by employing three-dimensional magnetization-prepared rapid acquisition gradient echo (3D MPRAGE) protocol. Acquisition parameters covering the whole brain included: repetition time (TR) = 2,300 ms, echo time (TE) = 2.98 ms, inversion time = 900 ms, thickness = 1 mm, gap = 0 mm, field of view (FOV) = 256 mm × 256 mm, matrix = 256 × 256, and flip angle = 9°.

Kuang L., Cui D., Jiao Q., Guo Y., Cao W., Gao W., Qiu J., Su L, & Lu G. (2020). Alterations of Cognition and Cerebral Ventricle Volume in Manic and Euthymic Pediatric Bipolar Disorder. Frontiers in Psychiatry, 11, 593629.

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Functional MRI Acquisition Protocol

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MR data were acquired with a Siemens 3.0 T Trio scanner (Berlin/Munich, Germany) with a 12-channel phased-array head coil. Functional data were obtained using a 2-shot T₂*-weighted echo-planar imaging (EPI) sequence sensitive to blood oxygenation level-dependent (BOLD) contrast (TR = 2000 msec, TE=30 msec, 192 mm field of view, in-plane resolution 3.0 mm × 3.0 mm). Each functional volume contained 37 contiguous 3.0 mm-thick axial slices separated by a 0.5mm inter-slice gap acquired in an interleaved manner. Whole-brain T₁-weighted scans were acquired for anatomical localization. Functional data were realigned to the first volume acquired and spatially smoothed with a 6.0 mm full-width at half-maximum Gaussian kernel.

Lee T.G, & Grafton S.T. (2014). Out of control: Diminished prefrontal activity coincides with impaired motor performance due to choking under pressure. NeuroImage, 105, 145-155.

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Multimodal MRI Acquisition Protocol

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LUMC scans were acquired using a Philips 3.0T Achieva MRI scanner with an 8-channel SENSE head coil. OCMR scans were acquired using a Siemens 3.0T Trio scanner with a 12-channel head coil. Participants were instructed to keep their eyes closed (LUMC) or open (OCMR), to think of nothing in particular (OCMR) and to remain awake. The scan parameters used for the high-resolution 3D anatomical T1-weighted and for the R-fMRI T2*-weighted images are shown in Table 1.

Feis R.A., Smith S.M., Filippini N., Douaud G., Dopper E.G., Heise V., Trachtenberg A.J., van Swieten J.C., van Buchem M.A., Rombouts S.A, & Mackay C.E. (2015). ICA-based artifact removal diminishes scan site differences in multi-center resting-state fMRI. Frontiers in Neuroscience, 9, 395.

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Structural MRI Processing Pipeline

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All participants underwent a structural T1-weighted MPRAGE MRI acquired from a SIEMENS 3.0T Trio scanner with an 8-channel coil using the following parameters: repetition time=1620 msec; echo time=3 msec; slice thickness=1.0 mm; flip angle=15°; matrix=192×256, and in-plane resolution=0.9×0.9 mm. MRI volumes were preprocessed using highly accurate (Klein et al., 2010 (link)) PipeDream (http://sourceforge.net/projects/neuropipedream/) and Advanced Normalization Tools (ANTs)(Avants et al., 2008 (link)), as previously reported (Avants et al., 2011 (link)). Briefly, PipeDream deforms each individual dataset into a standard local template space in a canonical stereotactic coordinate system. A diffeomorphic deformation was used for registration that is symmetric to minimize bias toward the reference space for computing the mappings, and topology-preserving to capture the large deformation necessary to aggregate images in a common space. These algorithms allow template-based priors to guide GM. We then computed a registration based measure of cortical thickness (Das et al., 2009 (link)) and smoothed the cortical thickness images using a 1.5mm sigma kernel.

McMillan C.T., Avants B.B., Cook P., Ungar L., Trojanowski J.Q, & Grossman M. (2014). The power of neuroimaging biomarkers for screening frontotemporal dementia. Human Brain Mapping, 35(9), 4827-4840.

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Structural MRI of Rhesus Monkeys

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MR images were previously acquired for each rhesus monkey on a Siemens 3.0T Trio scanner, using an extremity coil. T1-weighted images were acquired in the coronal plane with a spin echo sequence (TE = 3.34, TR = 2530, flip angle = 7°, section thickness = 0.50 mm, field-of-view = 140 mm, image matrix = 256×256×176 pixels, matrix size = 0.547 × 0.547 × 0.500 mm). Non-brain tissue was removed and the image cropped to 176 × 176 × 176 pixels using MEDx software (Medical Numerics Inc., Germantown, MD, USA) before co-registration with PET images.

Gallezot J.D., Esterlis I., Bois F., Zheng M.Q., Lin S.F., Kloczynski T., Krystal J.H., Huang Y., Sabri O., Carson R.E, & Cosgrove K.P. (2014). Evaluation of the sensitivity of the novel α4β2* nicotinic acetylcholine receptor PET radioligand 18F-(−)-NCFHEB to increases in synaptic acetylcholine levels in rhesus monkeys. Synapse (New York, N.Y.), 68(11), 556-564.

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FMRI Acquisition and Preprocessing Protocol

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Functional MRI scans were acquired with a Siemens 3.0 T Trio scanner at the MR Research Center of Southwest University. Stimuli were programmed with E-prime software 2.0 (Psychology Software Tools, Inc., Pittsburgh, PA) and projected onto a translucent screen via a projector. The subjects viewed the stimuli through a mirror attached to the head coil. Head motion was minimized by placing pillows and cushions around the head. Ear plugs were used to reduce noise in the scanner. Functional imaging consisted of an echo planner imaging with gradient echo (EPI GRE) sequence (TR = 2000 ms, TE = 30 ms, flip angle = 90°, FOV = 64 × 64 mm², 32 interleaved descending slices, voxel size = 3.44 × 3.44 × 3.00 mm² with 1-mm intra-slice gap). The five initial scans of each session were dummy scans that were used to equilibrate the state of magnetization and were excluded from the analysis. Anatomical reference images, acquired after the functional imaging, consisted of a 3-D GRE T1-weighted sequence (TR = 1900 ms, TE = 2.52 ms, flip angle = 9°, FOV = 256 × 256 mm², voxel size = 1 × 1 × 1 mm³). Head motion was evaluated on the MRI workstation as soon as the scans ended.

Zhang Y., Wang T., Huang P., Li D., Qiu J., Shen T, & Xie P. (2015). Free Language Selection in the Bilingual Brain: An Event-Related fMRI Study. Scientific Reports, 5, 11704.

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Multimodal Neuroimaging Protocol

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Participants were scanned on a Siemens 3.0T Trio scanner. We acquired T1-weighted structural images using an MPRAGE protocol (repetition time [TR] = 1620 ms, echo time [TE] = 3 ms, flip angle = 15°, 1 mm slice thickness, 192 × 256 matrix, voxel size = .98 × .98 × 1 mm). In healthy adults, we also collected BOLD fMRI images (TR = 3 s, effective TE = 30 ms, flip angle = 90°, 64 × 64 matrix, 3 mm isotropic voxels, with fat saturation).

Bonner M.F., Price A.R., Peelle J.E, & Grossman M. (2015). Semantics of the visual environment encoded in parahippocampal cortex. Journal of cognitive neuroscience, 28(3), 361-378.

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Structural and Functional MRI Imaging Protocol

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A Siemens 3.0T Trio scanner (Siemens, Erlangen, Germany) was used for the MRI data acquisition. High-resolution T1 structural images were acquired using a magnetization-prepared rapid gradient echo (MPRAGE) sequence with the following parameters: repetition time (TR) = 2,530 ms; echo time (TE) = 2.98 ms; flip angle = 7°; axial slices = 192 layers; thickness = 1.0 mm; field of view (FOV) = 256 × 256 mm²; resolution matrix = 64 × 64; and voxel size = 0.5 × 0.5 × 1 mm3. Functional images were obtained using a planar echo-imaging pulse sequence (echo-planar imaging) (EPI) with the following parameters: TR, 2,000 ms; TE, 30 ms; flip angle, 90°; axial slices, 62 layers; slice thickness, 2 mm; FOV, 224 mm × 224 mm; resolution matrix = 64 × 64; and voxel size = 2 × 2 × 2 mm³.

Liu M., Zhang X., He Z., Liang Y., Zou B., Ma X., Gu S, & Wang F. (2023). Opposite effects of estradiol and progesterone on woman's disgust processing. Frontiers in Psychiatry, 14, 1161488.

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