Ethyl acetate

Manufactured by AppliChem

Sourced in Germany

Ethyl acetate is a colorless, volatile, and flammable organic solvent. It is commonly used as a solvent in various industrial and laboratory applications, including as a component in nail polish removers, glues, and paint thinners.

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Lab products found in correlation

4 protocols using ethyl acetate

Quantitative Analysis of Paraquat and Diquat

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Paraquat (99.2%, batch number 6320x) and diquat (99.8%, batch number 20 160 323) were purchased from Sigma‐Aldrich Labor Chemikalien GMBH (Milwaukee, USA) and Shanghai Pesticide Research Institute Co., Ltd., respectively (Shanghai, China). Acetonitrile (chromatographic pure, batch number 0 000 152 366) and methanol (chromatographic pure, batch number 0 000 189 995) were provided by JT Baker (Phillipsburg, USA). Sodium heptane sulfonate (batch number 20171012s1210) was provided by Agela Technologies (Tianjin, China). Ethyl acetate (chromatography pure, batch number 151 331 612) was provided by AppliChem (Darmstadt, Germany). Phosphoric acid (85%, chromatography pure) was provided by Fisher Scientific‐Janssen Physicalaan (Geel, Belgium). Ammonium formate (chemical pure, batch number 990 215) and potassium dihydrogen phosphate (>99.5%, analytical pure) were provided by China Pharmaceutical (Group) Shanghai Chemical Reagent Co., Ltd. (Shanghai, China) and Shandong Chemical Research Institute (Jinan, China), respectively. Purified water was provided by Hangzhou Wahaha Group Co., Ltd. (Hangzhou, China). Blank human plasma was obtained from healthy donors collected and stored immediately at −20°C until analysis, which was approved by the ethics committee of Qilu Hospital of Shandong University. The signed informed consent was obtained from each donor.

Yuan G., Li R., Zhao Q., Kong X., Wang Y., Wang X, & Guo R. (2020). Simultaneous determination of paraquat and diquat in human plasma by HPLC‐DAD: Its application in acute poisoning patients induced by these two herbicides. Journal of Clinical Laboratory Analysis, 35(3), e23669.

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Quantification of antihypertensive drugs

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Reference substances of lercanidipine, telmisartan and valsartan were obtained from Sigma-Aldrich GmbH (Steinheim, Germany). Amlodipine and candesartan, as well as the deuterated internal standards (IS) diazepam-d₅, lorazepam-d₄ and nordiazepam-d₅ were purchased from LGC Standards GmbH (Wesel, Germany).
Acetonitrile was obtained from Karl Roth GmbH (Karlsruhe, Germany) and ethyl acetate from AppliChem (Darmstadt, Germany). Further chemicals and solvents used were supplied by Sigma-Aldrich GmbH (Steinheim, Germany). All reagents and solvents were either of analytical or LC grade.

Ritscher S., Hoyer M., Georges C., Wunder C., Wallemacq P., Persu A., Obermüller N, & Toennes S.W. (2020). Benefit of serum drug monitoring complementing urine analysis to assess adherence to antihypertensive drugs in first-line therapy. PLoS ONE, 15(8), e0237383.

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Quantitative Analysis of Pharmaceutical Drugs

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Reference substances furosemide, torasemide, atenolol, bisoprolol and metoprolol were obtained from Sigma-Aldrich GmbH (Steinheim, Germany). Hydrochlorothiazide (HCT), canrenone and nebivolol, as well as the deuterated internal standards (IS) ketamine-d₄, haloperidol-d₄, diazepam-d₅, quetiapine-d₈, oxazepam-d₅ and methadone-d₉ were purchased from LGC Standards GmbH (Wesel, Germany). HCT-d₂ was obtained from Toronto Research Chemicals (North York, Canada).
Acetonitrile was obtained from Karl Roth GmbH (Karlsruhe, Germany) and ethyl acetate from AppliChem (Darmstadt, Germany). Further chemicals and solvents used were supplied by Sigma-Aldrich GmbH (Steinheim, Germany). All reagents and solvents were either of analytical or LC grade.

Ritscher S., Hoyer M., Wunder C., Obermüller N, & Toennes S.W. (2019). Evaluation of the dose-related concentration approach in therapeutic drug monitoring of diuretics and β-blockers – drug classes with low adherence in antihypertensive therapy. Scientific Reports, 9, 15652.

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Quantitative Analysis of 4-FA

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Reference substance of 4-FA and the deuterated internal standard 4-FA-d 5 (ISTD) were purchased from LGC Standards (Wesel, Germany). UPLC-grade water and UPLC-grade acetonitrile were purchased from VWR Chemicals (Darmstadt, Germany), ethyl acetate was from AppliChem (Darmstadt, Germany), and methanol was from Sigma-Aldrich (Steinheim, Germany). All other reagents and solvents were purchased from Merck (Darmstadt, Germany) and were of analytical or HPLC grade.

Meier S.I., Petzel-Witt S., Schubert-Zsilavecz M., de Sousa Fernandes Perna E.B., Theunissen E.L., Ramaekers J.G, & Toennes S.W. (2020). Analysis of 4-fluoroamphetamine in cerumen after controlled oral application. Drug testing and analysis, 12(7).

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