3,4-Dihydroxybenzaldehyde, 1-bromohexadecane, boron trifluoride diethyletherate (BF3·Et2O), trifluoroacetic acid and 2-(diphenylphosphino)benzaldehyde were purchased from J&K Scientific Ltd. 2,4-Dimethyl-pyrrole was obtained from Nanjing Chemlin Chemical Industry Co. Ltd. Sodium hypochlorite (NaClO) and potassium dioxide (KO2), tert-butyl hydroperoxide (TBHP) were supplied by Sigma Aldrich. Other chemicals or solvents were purchased from Sinopharm Chemical Reagent Co. Ltd, such as hydrogen peroxide (H2O2), ferric chloride hexahydrate (FeCl3·6H2O), ferrous sulfateheptahydrate (FeSO4·7H2O), N,N-dimethylformamide (DMF), dimethyl sulfoxide (DMSO), triethylamine (Et3N), dichloromethane (CH2Cl2), et al. All chemicals and solvents were used directly without further purification unless otherwise noted. All air and moisture sensitive reactions were carried out under an argon atmosphere. Dry CH2Cl2 was obtained by refluxing and distilling over CaH2 under nitrogen. triethylamine was obtained by simple distillation.
Nuclear magnetic resonance (NMR) spectra were obtained from a Bruker 500 or 600 MHz spectrometer with TMS as an internal standard operating for 1H, 13C NMR and 31P NMR. Mass spectra were measured with a Bruker ultraflex MALDI TOF MS spectrometer. HRMS data were obtained on an Agilent 6224.
Nuclear magnetic resonance (NMR) spectra were obtained from a Bruker 500 or 600 MHz spectrometer with TMS as an internal standard operating for 1H, 13C NMR and 31P NMR. Mass spectra were measured with a Bruker ultraflex MALDI TOF MS spectrometer. HRMS data were obtained on an Agilent 6224.