Frame link planning system

Manufactured by Medtronic

Sourced in Sweden

The Frame Link planning system is a medical device used for pre-operative planning and intraoperative guidance during spinal surgery. It provides a computer-assisted platform to help surgeons visualize and plan the placement of spinal implants and instruments.

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Lab products found in correlation

Activa 3389s, by Medtronic (2 mentions) Leksell stereotactic system, by Elekta (2 mentions) Activa, by Medtronic (1 mentions) Activa rc, by Medtronic (1 mentions) Activa pc, by Medtronic (1 mentions)

3 protocols using frame link planning system

Bilateral Subthalamic Nucleus Deep Brain Stimulation Procedure

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All surgery was taken by the same surgical team. All patients underwent bilateral STN-DBS. Leksell Stereotactic System (Elekta, Stockholm, Sweden) and the Frame Link planning system (Medtronic, Minneapolis, MN) were used for preparation of surgery. According to the Schaltenbrand-Wahren atlas, the tentative target site was 2 mm posterior to the midpoint of the anterior–posterior commissure (AC-PC) line, 12 mm lateral to the AC-PC line, and 4 mm ventral to the AC-PC line. Target sites were corrected based on T2-weighted MRIs. The target was reconfirmed physiologically with an intraoperative microelectrode recording, just prior to performing the test stimulation studies. After all, quadripolar DBS electrodes (Activa 3389s, Medtronic) were implanted bilaterally in stereotactic guide.
After general anesthesia induced, implantable pulse generators (Activa RC Medtronic) were implanted subcutaneously in the subclavian pockets of the chest wall and connected to the DBS leads subcutaneously. Imagines of computed tomography postoperative and MRI preoperative were superimposing in Frame Link planning system to insure the local accuracy of electrode placement.

Li H., Liang S., Yu Y., Wang Y., Cheng Y., Yang H, & Tong X. (2020). Clinical experience of comprehensive treatment on the balance function of Parkinson's disease. Medicine, 99(19), e20154.

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Bilateral Subthalamic Nucleus Deep Brain Stimulation Protocol

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All surgeries were performed by the same surgical team. All patients underwent bilateral STN-DBS. The Leksell Stereotactic System (Elekta, Stockholm, Sweden) and Frame Link planning system (Medtronic, Minneapolis, Minnesota, USA) were used for surgery preparation. According to the Schaltenbrand-Wahren atlas, the tentative target site was 2 mm posterior to the midpoint of the anterior–posterior commissure (AC-PC) line, 12 mm lateral to the AC-PC line, and 4 mm ventral to the AC-PC line. Target sites were corrected based on T2-weighted MRI. The target was reconfirmed physiologically by an intraoperative microelectrode recording prior to performing the test stimulation studies. Quadripolar DBS electrodes (Activa 3389s, Medtronic) were implanted bilaterally as a stereotactic guide.
After inducing general anesthesia, implantable pulse generators (Activa RC Medtronic) were implanted subcutaneously in the subclavian pockets of the chest wall and connected to the DBS leads. Postoperative computed tomography images and preoperative MR images were superimposed in the Frame Link planning system to insure the local accuracy of electrode placement.

Li H., Liang S., Yu Y., Wang Y., Cheng Y., Yang H, & Tong X. (2020). Effect of Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) on balance performance in Parkinson's disease. PLoS ONE, 15(9), e0238936.

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Stereotactic Deep Brain Stimulation Implantation Protocol

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All surgical interventions were performed by experienced functional neurosurgeons (LS, MO, PK). After instillation of either LA or SB, a Riechert-Mundinger stereotactic frame (Inomed, Emmendingen, Germany) was mounted on the patients' skull via four transcutaneous pin fixations (two frontal and occipital, respectively). Following stereotactic CT scan with contrast agent the patients were transferred to the OR. Direct targeting was performed using the FrameLink planning system (Medtronic, Minneapolis, Minnesota, USA). DBS implantation was carried out by a frame-mounted drill (Precisis AG, Heidelberg, Germany) burr hole trepanation. Brain penetration was exclusively performed at systolic BP values under 160
mmHg. An experienced neurologist conducted the intraoperative neurophysiological and clinical assessment. After final lead placement, an immediate postoperative native stereotactic CT was performed to verify the definite lead location and to exclude potential ICH. The implanted programmable generator (IPG) (Activa PC, Medtronic, Minneapolis, Minnesota, USA) was implanted under GA either subsequently or during a second surgery after three days.
Pin placement for stereotactic frame fixation was defined as the start of the surgery (time point 0). 3).

Krauss P., Marahori N.A., Oertel M.F., Barth F, & Stieglitz L.H. (2018). Better Hemodynamics and Less Antihypertensive Medication: Comparison of Scalp Block and Local Infiltration Anesthesia for Skull-Pin Placement in Awake Deep Brain Stimulation Surgery. World neurosurgery, 120.

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