Macro interpreter software

Manufactured by Sable Systems

Macro Interpreter software is a utility that allows users to create and execute customized macros for various applications. It provides a simple interface for recording, editing, and running repetitive tasks, improving workflow efficiency.

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Lab products found in correlation

Oneclick macro, by Sable Systems (1 mentions) Promethion high definition behavioral phenotyping system, by Sable Systems (1 mentions)

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Macro Interpreter (2 citations)

2 protocols using macro interpreter software

Comprehensive Mouse Behavioral Phenotyping

Cited 3 times

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Also in the final week of the study, mice were placed in Sable System Promethion High-Definition Behavioural Phenotyping cages (Sable Systems International, Las Vegas, NV) on a 12-hour light/dark cycle for a span of 48 hours (33 (link)–35 (link)). This system allows for real-time behavior analysis of mice in a home-cage setting. Individual cages (interior dimensions of 31.5 × 15.5 (floor), up to 34.5 × 19.0 (ceiling) × 13.0 cm tall) include a ceiling-mounted food hopper and water bottle. Cages include a ceiling-mounted small “house” into which mice can climb. X- and Y-axis (horizontal plane) photoelectric beam motion detectors are positioned around the cage. While in the cages, any mice who had wheels in their housing cages had wheels installed during their time in the cages which they had ad libitum access to. Mice also had ad libitum access to food and water as well as a housing unit all of which had mass monitors to measure any changes. Behavioural phenotyping was analyzed based on movement patterns, behaviours (interactions with cage elements), resting time, fine movement, and overall movement were recorded and averaged into 30-minute intervals using Sable Systems data acquisition software (36 (link), 37 (link)). Data were analyzed using Sable Systems International Macro Interpreter software (v.2.48) using One-Click Macro.

Mohammad A., Finch M.S., Sweezey-Munroe J, & MacPherson R.E. (2022). Voluntary wheel running alters markers of amyloid-beta precursor protein processing in an ovarian hormone depleted model. Frontiers in Endocrinology, 13, 1069404.

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β3-Adrenoreceptor Agonist Effects on Metabolic Physiology

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Mice were placed, single-housed, in metabolic cages (Sable Systems International, Promethion high-definition behavioral phenotyping system) housed in thermal cabinets set to 30°C with a 12-hour light and 12-hour dark schedule. The following morning at Zeitgeber (ZT) ZT3, mice were injected with vehicle (saline) and placed back in the metabolic cages to monitor the stress response to i.p. injection. The next morning (at ZT3), the same volume of the β3-adrenoreceptor agonist, CL 316,243, was administered i.p. at 1mg/kg, and mice were placed back in the metabolic cages. Saline and Cl 316,243 responses were followed every 3 minutes for 90 minutes. Mass-dependent variables (VO₂, VCO₂, and energy expenditure) were not normalized to body weight. Oxygen consumption (VO₂), carbon dioxide expiration (VCO₂), energy expenditure (kcal), respiratory exchange ratio, and total physical movement (meters; measured by infrared beam breaks) were recorded every 3 min using Sable Systems data acquisition software (IM-3 v.20.0.3). Data were parsed/analyzed using Sable Systems International MacroInterpreter software (v.2.41) using One-Click Macro (v2.37).

Rahbani J.F., Roesler A., Hussain M.F., Samborska B., Dykstra C.B., Tsai L., Jedrychowski M.P., Vergnes L., Reue K., Spiegelman B.M, & Kazak L. (2021). CKB controls futile creatine cycling in thermogenic fat. Nature, 590(7846), 480-485.

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