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Mydriacyl

Manufactured by Novartis
Sourced in Denmark, United States

Mydriacyl is a pharmaceutical product used for pupil dilation during eye examinations. It contains the active ingredient tropicamide, which is a mydriatic agent that causes temporary enlargement of the pupil.

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2 protocols using mydriacyl

1

Cycloplegic Refraction Protocol

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After the preoperative measurements were performed, one drop of metaoxedrine x3 (Skanderborg Pharmacy, Skanderborg, Denmark), one drop of mydriacyl 10 mg/ml × 3 (Novartis, Basel, Switzerland) and one drop of cyclopentolate 1% × 3 (Alcon Novartis, Forth West, Texas, USA) were instilled in both eyes every ten minutes until three doses of each drug have been administered. A cycloplegic subjective refraction was then performed to ensure a VA of 6/6 (0.00 logMAR) or better in both eyes, and then, ATRRANDOT and ATRTNO were re‐measured to examine reproducibility.
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2

Evaluating MMP-9 Immunoassay Interference in Eye Drops

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To investigate interactions between the MMP-9 immunoassay and components within eye drops, 10 μl of rhMMP-9 (200 ng/ml) was applied to the sample collector, followed by addition of 10 μl of eye drop sample. The following eye drops were used: Elazop (brinzolamide/timolol; Novartis, Basel, Switzerland), Alphagan-P (brimonidine tartrate 0.15%; Allergan, Dublin, Ireland), Isopto Carpine (pilocarpine hydrochloride 2%; Novartis), Bronuck (bromfenac sodium 0.1%; TaeJoon, Seoul, Korea), Cravit (levofloxacin 0.5%; Santen, Tokyo, Japan), Diquas (Diquafosol sodium 3%; Santen), Ikervis (cyclosporine A cationic emulsion 0.1%; Santen, Evry, France), Lotemax (loteprednol etabonate 0.5%; Bausch & Lomb, Rochester, NY, USA), Pazeo (olopatadine hydrochloride 0.7%; Novartis), Lastacaft (alcaftadine 0.25%; Allergan), Mydrin-P (tropicamide 0.5%/phenylephrine 0.5%; Santen), Mydriacyl (tropicamide 1%; Novartis), Cyclogyl (cyclopentolate HCl 1%; Norvatis), Isopto Atropine (atropine hydrochloride 1%; Novartis), and Refresh Tears (carboxymethylcellulose sodium 0.5%; Allergan). The test line was photographed after 10 and 20 min, the density was measured, and the results were compared with a control sample (200 ng/ml of rhMMP-9; 20 μl).
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