Taselisib was purchased from Medchemexpress (Monmouth Junction, NJ, USA), whereas CYC065 was provided by Cyclacel. Both compounds were dissolved in DMSO as a 10 mM stock solution and diluted in culture medium immediately before use.
Taselisib
Manufactured by MedChemExpress
Sourced in United States
Taselisib is a laboratory product manufactured by MedChemExpress. It functions as a phosphoinositide 3-kinase (PI3K) inhibitor, specifically targeting the alpha isoform of the enzyme.
Automatically generated - may contain errors
Lab products found in correlation
Capivasertib, by MedChemExpress (1 mentions)
Docetaxel, by MedChemExpress (1 mentions)
Pan akt, by Cell Signaling Technology (1 mentions)
Ab189490, by Abcam (1 mentions)
Mk2206, by MedChemExpress (1 mentions)
P akt ser473, by Cell Signaling Technology (1 mentions)
F3879, by Merck Group (1 mentions)
Defactinib, by MedChemExpress (1 mentions)
Cytochalasin d, by MedChemExpress (1 mentions)
F4 80, by Abcam (1 mentions)
Cd11b, by Abcam (1 mentions)
Evans blue, by Merck Group (1 mentions)
Ly294002, by Merck Group (1 mentions)
Dextran sulfate sodium (dss), by MP Biomedicals (1 mentions)
Saracatinib, by MedChemExpress (1 mentions)
2 protocols using taselisib
1
Taselisib and CYC065 compound dissolution
2
Investigating Inflammatory Markers and Signaling Pathways
Check if the same lab product or an alternative is used in the 5 most similar protocols
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The antibodies used for immunoblotting included: mouse monoclonal antibody against GAPDH (RM2002; Beijing Ray, Beijing, China); rabbit antibodies against Fg (ab189490; Abcam, Cambridge, MA), pan-Akt (4691; Cell Signaling Technology, Danvers, MA), p-Akt (Ser473) (4060; Cell Signaling Technology), and goat anti-mouse (R3001, Beijing Ray) or goat anti-rabbit (R3002, Beijing Ray) horseradish peroxidase–conjugated secondary antibody.
The antibodies used for immunohistochemical staining included: CD11b (ab133357; Abcam), S100A9 (73425; Cell Signaling Technology), MPO (ab9535; Abcam), F4/80 (ab111101; Abcam), and CD31 (3528; Cell Signaling Technology).
Other reagents included DSS (36,000–50,000 kD; MP Biomedicals, Santa Ana, CA), Evans blue (E2129; Sigma-Aldrich, St. Louis, MO), Fg (F3879; Sigma-Aldrich), GPRP acetate, LY294002, taselisib, capivasertib, MK 2206, defactinib, Y15, saracatinib, WH-4-023, L-NIO, L-NMMA, ML-7, MLCK inhibitor, docetaxel, Jasplakinolide, and Cytochalasin D (MedChemExpress, Monmouth Junction, NJ).
The antibodies used for immunohistochemical staining included: CD11b (ab133357; Abcam), S100A9 (73425; Cell Signaling Technology), MPO (ab9535; Abcam), F4/80 (ab111101; Abcam), and CD31 (3528; Cell Signaling Technology).
Other reagents included DSS (36,000–50,000 kD; MP Biomedicals, Santa Ana, CA), Evans blue (E2129; Sigma-Aldrich, St. Louis, MO), Fg (F3879; Sigma-Aldrich), GPRP acetate, LY294002, taselisib, capivasertib, MK 2206, defactinib, Y15, saracatinib, WH-4-023, L-NIO, L-NMMA, ML-7, MLCK inhibitor, docetaxel, Jasplakinolide, and Cytochalasin D (MedChemExpress, Monmouth Junction, NJ).
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