All procedures were performed by the same interventional radiologists (DJ and XH). The body position was determined according to the location of the tumor with the aim of puncture facilitation. A 64-row CT (Brilliance Big Bore, Siemens, Germany) scan was carried out to localize the tumor in the axial CT image with a thickness of 3 mm (parameter: voltage 120 kV, current 90 mA). The puncture route was mapped to avoid pulmonary bullae, severe emphysema, crossing interlobar fissures, and so on. Under the repeated cCT scan, the microwave applicator was gradually inserted into the tumor until an active tip puncture was performed throughout the whole tumor (step-by-step strategy) according to the operator’s experience. The ablation parameters were the same as those described in the C-arm CT group. For tumors larger than 3 cm, 2 puncture needles could be used simultaneously, or repeated adjustment of the puncture may have been needed using a single microwave applicator. The post-ablation image standards were the same as those in the C-arm CT group.
Brilliance big bore
Manufactured by Siemens
Sourced in Germany
The Brilliance Big Bore is a medical imaging device designed for diagnostic and treatment planning applications. It features a large patient aperture to accommodate a wide range of body sizes and clinical requirements. The core function of the Brilliance Big Bore is to capture high-quality images for medical professionals to analyze and diagnose patient conditions.
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Lab products found in correlation
4 protocols using brilliance big bore
1
Microwave Ablation Guided by Repeated CT Scans
2
Ventilation Mapping for NSCLC Radiotherapy
3
Tumor Ablation via Caudal-Cranial Puncture
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In the cCT group, the puncture was done without the use of a navigation tool. The same interventional radiologists mentioned above performed all the punctures. A 64-row CT scan was performed to localize the tumor in the axial CT image (Brilliance Big Bore, Siemens, Germany) with a current of 200 mA, a voltage of 120 kV, and a thickness of 3 mm. The basic principle of the puncture is to avoid damage to the diaphragm, lung tissue, and the ribs to the maximum possible extent. Based on the operator’s experience, all puncture routes would travel from the caudal to the cranial side, with the center of the tumor as the puncture target. Because the axial image showed no full view of the oblique puncture applicator, the puncture was performed using a step-by-step strategy until the microwave applicator reached the center of the tumor. The ablation parameters in the cCT group were the same as those described for the CBCT group.
4
Retrospective Study of Radiation Therapy Protocols
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Between January 2022 and May 2022, a cohort of additional 50 treated plans with different tumor stages and prescribed doses were randomly and retrospectively selected. All patients were staged according to the American Joint Committee on Cancer (AJCC) Manual for Staging of Cancer, 8th edition. Patients had previously been scanned using either a Philips Brilliance Big Bore or Siemens Syngo CT scanner. These CT images were transferred to the Pinnacle 3 TPS (version 16.2, Philips Medical Systems, Fitchburg, WI). The targets were then manually delineated by the radiation oncologist on these CT images with the help of a contrast-enhanced diagnostic CT. Generally, Clinical Target Volume (CTV) was expanded by 5mm from Gross Target Volume (GTV) and PTV was expanded by 5mm from CTV. If Planning Gross Target Volume (PGTV) needed to be delineated, a 5 mm margin between the PTV and PGTV were considered, though these margins could have been subjected to adaptations for each specific clinical case. The OARs included lung, heart, cord, cord PRV, trachea, esophagus, liver and so on. The dose constraint applied for planning are provided in Supplementary Material 2.
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