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Clonotyping system kit

Manufactured by Southern Biotech
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The Clonotyping System Kit is a laboratory equipment designed for the analysis of T-cell receptor (TCR) and B-cell receptor (BCR) repertoires. The kit provides the necessary components and protocols for the identification and quantification of unique T-cell and B-cell clones within a sample. The core function of this product is to enable researchers to study the diversity and dynamics of the adaptive immune system.

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Close spelling variants of this product

SBA Clonotyping system-horseradish peroxidase (HRP) kit Clonotyping system-HRP kit SBA Clonotyping System-HRP kit

2 protocols using clonotyping system kit

1

Quantifying Antibody Response to NP-Ficoll

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Mice were injected intravenously with 50 μg of NP-Ficoll dissolved in a volume of 200 μl of PBS. One week after immunization, serum IgG3 and IgM titers were measured using the Clonotyping System Kit (5300-05, Southern Biotech).
Zhao Z., Luo Z., Yang Q., Chang H., Liu P., Li Z., Guo S., Zhou C., Song J, & Cao W. (2019). Neutrophil-Derived MRP14 Supports Plasma Cell Commitment and Protects Myeloma Cells from Apoptosis. Journal of Immunology Research, 2019, 9561350.
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2

Immune Response Quantification in Mice

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To analyze the immune response, WT or pdgfrb-cre::Lama5fl/fl mice were immunized by subcutaneous injections of 50 μg OVA323-339 or NP-CG in complete Freund’s adjuvant (1:2 mixture). At 1 week after immunization, serum antibody titers were measured using the Clonotyping System Kit (Southern Biotech).
Song J., Deshpande T., Zhang X., Hannocks M.J., Lycke N., Cardell S.L, & Sorokin L. (2023). The extracellular matrix of lymph node reticular fibers modulates follicle border interactions and germinal center formation. iScience, 26(5), 106753.
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