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Stata software version 16

Manufactured by StataCorp
Sourced in United States

Stata software version 16 is a comprehensive, integrated statistical software package developed by StataCorp. It provides a wide range of data management, statistical analysis, and graphical tools for researchers, analysts, and professionals across various fields. The software offers a user-friendly interface and a robust set of features to handle complex data analysis tasks.

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275 protocols using stata software version 16

1

Race, Income, and Postoperative Mortality

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We compared baseline characteristics of White and Black children. To calculate risk-adjusted in-hospital mortality rates by race and household income categories, we fitted a logistic regression model (details available in eMethods in the Supplement). We then used the margin postestimation command in Stata software, version 16.1 (StataCorp LLC), to estimate risk-adjusted mortality rates and 95% CIs.
To evaluate whether highest household income quartile status modified the association between race and the risk of postoperative death, we fitted a multivariable logistic regression model including a 2-way interaction between race and median income of the zip code of residence. The zip code of residence was used as a binary variable to indicate whether patients belonged to the highest income quartile.16 (link)Results were reported as odds ratios (ORs) with corresponding 95% CIs. All analyses were performed using Stata software, version 16 (StataCorp LLC). The significance threshold was 2-tailed P < .05.
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2

Survival Analysis of Cohort Study

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Differences of variables between the individual groups were analyzed using student t test and Mann-Whitney U test based on variables types. Factors associated with the survival were assessed by univariate analysis and multivariate analysis Cox regression. Results were reported as hazard ratios (HR) with 95% confidence intervals (CI). The Kaplan-Meier method with log rank test was used to compare OS and DFS between different groups. Stata software version 16.0 (Stata Corp LLC, Texas, USA) was used. A two-tailed p < 0.05 were considered significant for all tests.
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3

Multivariate Analysis of Survival Outcomes

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Mean ± standard deviation (SD) was used for the statistical description for normally distributed continuous data, and frequency with percentage was used for the description of the enumeration data. Parameters associated with the outcomes were assessed by univariate analysis and multivariate analysis using Cox regression. Only covariates significantly associated with outcomes according to the univariate analysis (two-sided p-value < 0.10) are shown and included in the multivariate model. The Kaplan–Meier analysis with log rank test was used to compare survival between different groups. Results were reported as hazard ratios (HR) with a 95% CI. Stata software version 16.0 (Stata Corp LLC, Texas, USA) was used for other statistics; p < 0.05 (two-sided) was considered significant for all tests.
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4

Postoperative Complications Analysis Protocol

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Quantitative variables were measures of central tendency type average (x̄ or Median [Me]) with their respective measures of dispersion standard deviation (SD) and interquartile range (IQR) depending on the normality of their distribution, which was calculated using the Shapiro–Wilk test. The descriptive analysis of qualitative variables was performed by calculating absolute and relative frequencies. For the comparison of the distribution of postoperative complications for clinical, surgical procedure‐related and postoperative variables, the chi‐square test or the Mann Whitney test was used for qualitative variables, depending on the result of the normality test; for the comparison of distributions of quantitative variables, the ANOVA test or the Kruskall–Wallis test was used, depending on the distribution of the variable.
In addition, a Poisson regression analysis was performed to determine the prevalence ratios (PR) associated with the significant variables in the bivariate analysis, with the presence of postoperative complications as the dependent variable. An analysis was performed controlling for possible confounding variables. Values of p < 0.05 were taken as significant. Data analysis was performed with the Stata software version 16.0 (StataCorp, Texas, USA).
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5

Comparing Industry and Non-Industry Trial Conduct

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We summarized the baseline characteristics of included trials by using standard descriptive statistics separately for industry- or non–industry-sponsored trials. We then assessed the percentage of trials in each of the status, duration, and recruitment categories described herein and reported discrepancies between planned and actual trial conduct by industry sponsorship status. Absolute and relative differences between anticipated and actual trial duration are presented as medians (IQRs) for trials completed with delays and discontinued trials. Similarly, differences between anticipated and actual recruitment are presented for discontinued trials and those completed without meeting their recruitment target. To determine whether industry sponsorship was associated with trials being completed on time or with full enrollment, we conducted χ2 tests with a 2-sided P < .05 used to indicate statistical significance. Data were prepared and analyzed between October 27, 2021, and June 30, 2022, using Stata software, version 16.0 (StataCorp LLC) and R software, version 4.1.2 (R Foundation for Statistical Computing).
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6

Ecological Analysis of COVID-19 Outcomes

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The Spearman correlation coefficient was used to assess the bivariate correlation between variables. Univariable and multivariable negative binomial regression also was used to investigate the association between the outcome variables of interest (death and incident cases) and the explanatory variables. For each country, person‐year (PY) was calculated based on the multiplication of the population by years from the start date. PY of exposure was included as an offset variable. We regressed single‐covariate on the death or case count; then, statistically significant variables at p = 0.5 were included in the multivariable model. 0.5 cutoff have chosen because of the small sample size of the ecologic studies for increasing statistical power. Finally, backward selection with a statistically significant level of 0.1 was run. Incidence rate ratio (IRR) (total cases divided by the mean population), mortality rate ratio (MRR) (total deaths divided by the mean population), and fatality risk ratio (FRR) (total deaths divided by the total cases) were calculated with STATA software version 16.0 (Stata Corp).
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7

Happiness Predictors in University Students

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We used one-sample K-S test to examine the normality of obtained data. Descriptive analyses about the sample’s socio-demographic, PA and sedentary behavior times, happiness level, depression, anxiety, stress status, and other related factors were conducted. Demographic, PA, happiness, and related variables of male and female students were compared using t-test or Mann-Whitney U-test for continuous variables and the chi-squared test for categorical variables. We used backward stepwise multiple regression analysis using subjective happiness level as the dependent variable to assess the effects of variables including PA, sedentary behavior, demographic, and other related factors in male and female students.
All statistical analyses were performed through the STATA software version 16.0 (Stata Corporation, College Station, TX, United States), with the significance level at the p-value of 0.05 (two-tailed).
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8

Survival Analysis in Biomedical Research

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Differences in variables between individual groups were analyzed using Student’s t test, the Mann-Whitney U-test and the chi-square test based on the variable type. Factors associated with survival were assessed by univariate and multivariate Cox regression analysis. Only covariates significantly associated with outcomes in the univariate analysis (2-sided P < 0.05) were included in the multivariate model. Parameters significantly associated with outcomes in multivariate model were presented. Results are reported as hazard ratios (HRs) with 95% confidence intervals (CIs). The Kaplan-Meier method with the log-rank test was used to compare OS and DFS between groups. Stata software version 16.0 (Stata Corp LLC, Texas, USA) was used. A 2-tailed P < 0.05 were considered significant for all tests.
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9

Evaluating Hospital Costs for Stroke Using PSM-DID Modeling

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All data analyses in this study were performed in STATA® software version 16.0 and the results are presented in tables.
The characterization of the municipalities and the expenses with hospital admissions for stroke was performed using descriptive statistics procedures (frequencies, means, and standard deviations). To verify the differences between means, the Student’s t-test was used. The evaluation of the effects of the HGP on hospitalization expenses for stroke was performed using a PSM-DID estimation strategy in a Fixed Effect data model for multiple periods. The analytical procedures involve validation tests of the estimation model and the empirical strategy (pre-tests), estimation of the PSM-DID model, and validation of the results found with the estimations (post-estimation).
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10

Burnout Prevalence and Associated Factors

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One-sample K-S test was used to detect the normality of obtained data. Descriptive analyses were used to describe the sample’s socio-demographic, burnout symptoms, and work-related factors.
Since there is no consensus on the diagnostic criteria for burnout syndromes, some suggested the three subscales should be treated as continuous measures (Rotenstein et al., 2018 (link)). We adopted this approach in our analysis. The Chi-square test examined the gender difference of burnout prevalence. The Kruskal–Wallis test or Pearson correlation analysis was conducted to test the correlation between related factors and EE, DP, and PA in male and female participants. After that, significant factors were involved in further regression analysis. As all endocrinologists nested in hospitals, multilevel linear regression analyses were conducted to identify independent factors associated with EE, DP, PA in male and female samples, respectively.
We performed all statistical analyses using the STATA software version 16.0 (Stata Corporation, College Station, TX, United States), with the significance level at the p-value of 0.05 (two-tailed).
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