Avanto and espree

Manufactured by Siemens

Sourced in Germany

The Avanto and Espree are magnetic resonance imaging (MRI) systems developed by Siemens. The Avanto is a 1.5 Tesla MRI system, while the Espree is a 1.5 Tesla wide-bore MRI system. Both systems are designed to acquire high-quality medical images for diagnostic purposes.

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Lab products found in correlation

Signa lx, by GE Healthcare (3 mentions) Magnevist, by Bayer (2 mentions) Signa hd, by GE Healthcare (1 mentions)

5 protocols using avanto and espree

Cardiac MRI Imaging Protocol for Left Ventricular and Left Atrial Analysis

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At the 2010 to 2012 examination, consenting participants underwent CMR imaging using 1.5‐T scanners (Avanto and Espree [Siemens Medical Systems, Erlangen, Germany] and Signa LX [GE Healthcare, Waukesha, WI]) with a 6‐channel phased array coil, as previously described.¹⁰ The cine images included coverage of the entire left ventricle (LV) and LA using short‐axis slices, 1 2‐chamber slice, and 1 4‐chamber view, scanned by steady‐state free precession sequences. LV mass and volumes were determined using CIM software version 6.2 (Auckland MRI Research Group, University of Auckland, Auckland, New Zealand). LA maximum and minimum volumes, total, active, and passive emptying fractions, and LA peak longitudinal strain were measured using Multimodality Tissue Tracking software version 6.0 (Toshiba, Japan) using 2‐ and 4‐chamber long‐axis images, as previously described.¹¹

Heckbert S.R., Jensen P.N., Austin T.R., Chen L.Y., Post W.S., Ambale Venkatesh B., Soliman E.Z., Floyd J.S., Sotoodehnia N., Kronmal R.A, & Lima J.A. (2021). Associations of Left Atrial Function and Structure With Supraventricular Ectopy: The Multi‐Ethnic Study of Atherosclerosis. Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 10(4), e018093.

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Cardiac MRI Imaging Protocol in MESA

Cited 1 time

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At Exam 5 (2010–2012), MESA participants without contraindications underwent CMR using 1.5T scanners (Avanto and Espree, Siemens Medical Systems; Signa LX, GE Healthcare). The MESA CMR protocol has been described previously and was uniform across all study sites.^{18 (link)} Briefly, LV volumes, myocardial mass, and functional measures were assessed by a cine steady‐state free precession sequence. Twelve short axis slices, one 4‐chamber view and one 2‐ chamber view, were acquired as described previously. Additionally, 3 tagged short-axis slices (base, mid, apex) were additionally obtained. The protocol for tagged CMR has been previously described.^{19 (link)} Finally, a subset (n=1,342) of consenting participants with estimated glomerular filtration rates (eGFR) >60 mL/min/1.73m² (Northwestern study site) or >45 mL/min/1.73m² (remaining study sites) underwent late gadolinium enhanced (LGE) CMR 15 minutes after administration of 0.15 mmol/kg dose of gadolinium based contrast agent (Magnevist, Bayer Healthcare Pharmaceuticals, Montville, NJ). All MESA CMR images were analyzed for structure and function in a core laboratory and at a single image analysis center (Johns Hopkins Medical Center, Baltimore, MD).

Patel R.B., Ning H., de Boer I.H., Kestenbaum B., Lima J.A., Mehta R., Allen N.B., Shah S.J, & Lloyd-Jones D. (2020). Fibroblast Growth Factor 23 and Long-Term Cardiac Function: The Multi-Ethnic Study of Atherosclerosis. Circulation. Cardiovascular imaging, 13(11), e011925.

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Cardiac MRI Protocol for Scar Imaging

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CMR was performed using 1.5T scanners (Avanto and Espree, Siemens
Medical Systems, Erlangen, Germany, and Signa HD, GE, Milwaukee, WI, USA) with a
6-channel anterior phased array coil. CMR protocol was uniform in all centers
and all studies were centrally evaluated by readers blinded to all other study
data. Left ventricular (LV) mass, volumes, and functional parameters were
determined by a cine steady state free precession sequence using CIM software
(version 6.2, Auckland MRI Research Group, University of Auckland, New
Zealand).
Myocardial scar was defined as focal LGE either in two adjacent short
axis slices or in one short axis and a long axis image at a corresponding
location using QMass (version 7.2; Medis, Leiden, the Netherlands). Myocardial
scars that involved subendocardium in a coronary artery distribution were
defined as “typical” scar. Myocardial scars predominantly
affecting midwall or subepicardium without subendocardial involvement in a
non-coronary artery distribution were defined as “atypical”
scar.

Turkbey E.B., Nacif M.S., Guo M., McClelland R.L., Teixeira P.B., Bild D.E., Barr R.G., Shea S., Post W., Burke G., Budoff M., Folsom A.R., Liu C.Y., Lima J.A, & Bluemke D.A. (2015). Prevalence of and factors associated with myocardial scar in a U.S. Cohort. JAMA, 314(18), 1945-1954.

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Cardiac Magnetic Resonance Imaging in MESA

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A subset of MESA participants (n=4980) without contraindications (internal metal fragments, implants, electrical devices, or severe claustrophobia) underwent CMR imaging at the MESA baseline examination by using 1.5‐T scanners (Avanto and Espree, Siemens Medical Systems, Erlangen, Germany) with a 6‐channel anterior phased‐array torso coil and corresponding posterior coil elements. LV function, dimensions, and myocardial mass were assessed by a cine steady‐state free precession sequence. Twelve short‐axis slices, one 4‐chamber view, and one 2‐chamber view were acquired as previously described.23 The endocardial and epicardial borders were contoured using a semiautomated method. The difference between the endocardial and epicardial areas for all slices was multiplied by slice thickness and section cap and then multiplied by the specific myocardial density (1.04 g/mL) to determine LV mass.

Almahmoud M.F., Soliman E.Z., Bertoni A.G., Kestenbaum B., Katz R., Lima J.A., Ouyang P., Miller P.E., Michos E.D, & Herrington D.M. (2018). Fibroblast Growth Factor‐23 and Heart Failure With Reduced Versus Preserved Ejection Fraction: MESA. Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 7(18), e008334.

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Standardized cMRI Acquisition in MESA

Cited 2 times

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Electrocardiographic gated cMRI was completed with 1.5‐Tesla magnets (Avanto and Espree, Siemens Healthineers, Malvern, PA; Signa LX, GE Healthcare, Chicago, IL) at all participating MESA centers at examination 5. The MESA cMRI image acquisition technique has been described extensively in the literature and was uniform across study sites.
¹⁴ (link),
¹⁵ (link) The protocol included acquisition of 12 short‐axis slices, one 4‐chamber view and one 2‐chamber view. In addition, short‐axis slices at the left ventricular (LV) base, midcavity, and apex were obtained. If contraindications were not present, contrast‐enhanced cMRI was performed. All eligible participants with estimated glomerular filtration rate >60 mL/(min×1.7 2 m²) or >45 mL/(min×1.72 m²) (depending on the study site) received 0.15 mmol/kg of gadolinium contrast (Magnevist, Bayer Healthcare Pharmaceuticals, Montville, NJ) for late gadolinium enhanced cMRI sequences.
¹⁴ (link)

Mathew D.T., Peigh G., Lima J.A., Bielinski S.J., Larson N.B., Allison M.A., Shah S.J, & Patel R.B. (2024). Associations of Circulating Vascular Cell Adhesion Molecule‐1 and Intercellular Adhesion Molecule‐1 With Long‐Term Cardiac Function. Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 13(6), e032213.

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