A 3.0 TMRI (Discovery 750) scanner from GE (United States) was used for MRI examination. During imaging, subjects wore eye masks and were instructed to remain awake and keep their heads still. Soft pads were used to reduce head movement, and headphones were used to reduce noise. rs-fMRI scans were obtained by using a gradient-recalled echo echo-planar imaging (GRE-EPI) sequence (repetition time (TR) =2,000 ms; echo time (TE) =30 ms; flip angle (FA) = 90 degrees; layer spacing =0 mm; layer thickness = 4 mm; field of view (FOV) =220 mm × 220 mm; matrix dimensions = 64 × 64. A fast gradient-echo sequence (magnetization-prepared rapid gradient echo, MPRAGE) was used to obtain high-resolution 3D T1-weighted structure images. The acquisition parameters were as follows: TR = 8.2 ms, TE = 3.2 ms, inversion time (TI) = 900 ms, FA = 9°, FOV = 256 mm × 256 mm, and voxel size = 1.3 mm × 0.9 mm × 5 mm; these parameters were used for image registration and functional positioning.
Discovery 750 scanner
Manufactured by GE Healthcare
Sourced in United States
The Discovery 750 is a compact and versatile CT scanner designed for a range of clinical applications. It features a 70 cm gantry bore and is capable of generating high-quality 3D images. The scanner's core function is to capture detailed anatomical data that can be used for diagnostic and treatment planning purposes.
Automatically generated - may contain errors
10 protocols using discovery 750 scanner
1
Resting-State fMRI and Structural MRI Protocol
2
Acquiring 3D T1-Weighted Brain MRI Data
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MRI data were acquired on a 3T General Electric Discovery 750 Scanner (GE Medical Systems, USA) using an eight‐channel head coil. Three‐dimensional anatomical images of the entire brain were obtained parallel to the anterior–posterior commissure line with a T1‐weighted structural image using a spoiled gradient echo sequence (3D SPGR). Imaging parameters: number of slices = 172, slice thickness = 1 mm, matrix size = 256 × 256, field of view = 256 mm, FA = 8°, TE = 3 ms (n = 20) or 5 ms (n = 17), TR = 10 ms (n = 20) or 11 ms (n = 17), scan duration = 3 min 52 s. Cushions were placed around participants’ heads to minimize head movement. Differences in TE and TR were due to a scanner software release upgrade, but these differences did not affect the image quality (see Results section).
3
Multimodal MRI Acquisition Protocol
4
Multimodal MRI Acquisition Protocol
5
Multi-Modal MRI Acquisition for Brain Imaging
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MRI data were acquired on a 3.0 Tesla Discovery 750 scanner (GE Healthcare, Milwaukee, WI, USA) with an eight-channel phased array head coil at the UC San Diego Center for Functional MRI. The MRI sequence included a three-plane localizer; a sagittal 3D fast spoiled gradient echo T1 -weighted volume optimized for maximum gray/white matter contrast (TE=3.2 ms, TR=8.1 ms, inversion time=600 ms, flip angle=8°, FOV=256×256 mm, matrix=256×192, slice thickness=1.2 mm, resampled to a resolution of 1×1×1.2 mm, scan time 8:27); and an axial 2D single-shot pulsed-field gradient spin-echo echo-planar diffusion-weighted sequence (45-directions, b-values=0, 500, 1500, 4000 s/mm2, one b=0 volume and 15 gradient directions for each non-zero b-value; TE=80.6 ms, TR=7 s, FOV=240×240 mm, matrix=96×96, slice thickness=2.5 mm, resampled to a resolution of 1.875×1.875×2.5 mm, scan time 6:34). An additional b=0 volume was collected prior to the diffusion sequence with reverse phase-encode polarity for B0 distortion correction.
6
Pediatric CT Scanning Protocol
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All included children were scanned using a Discovery 750 scanner (GE Healthcare, Waukesha, WI, USA) with a tube voltage of 120 KV, pitch of 1.375, and rotation speed of 0.8 seconds. Automatic tube current modulation (ATCM) was used to modulate the tube current, which was set between 10 and 350 mA. An age-dependent noise index (NI) was used for acquisition: NI = 12 for 0–12 months of age, NI = 15 for 1–2 years of age, and NI = 17 for 3–6 years of age. Images were retrospectively reconstructed into three series with a 5-mm slice thickness: series A using MBIR, series B using 60% of ASIR and 40% of conventional FBP, and series C using FBP. Since the children mostly refused to cooperate, CT scans were performed when the children were asleep or sedated with oral intake of 10% chloral hydrate (0.5 ml/Kg) half an hour before scanning. The scan covered the area between the entrance to the chest and the base of the lung.
7
Functional and Structural MRI Protocol
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Magnetic resonance imaging data were acquired on a 3T General Electric Discovery 750 Scanner (GE Medical Systems, USA) using an 8-channel head coil. Whole brain functional images were acquired sequentially with a gradient echo EPI sequence [38 slices, 3 mm slice thickness (ST), 0.3 mm interslice gap, 64 × 64 matrix size (MS), field of view (FOV) = 240 mm, flip angle (FA) = 74°, echo time (TE) = 32 ms, repetition time (TR) = 1900 ms]. Additionally, a T1-weighted structural image was obtained with a spoiled gradient echo sequence (3D SPGR, ST = 1 mm, no interslice gap, MS = 256 × 256, FOV = 256 mm, FA = 8°, TE = 5 ms, TR = 11 ms).
Participants were carefully instructed and supplied with hearing protection before entering the scanner. To minimize head motion, the head was stabilized with padding.
Participants were carefully instructed and supplied with hearing protection before entering the scanner. To minimize head motion, the head was stabilized with padding.
8
Acquisition of 3D Brain MRI
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MRI data were acquired on a 3T General Electric Discovery 750 Scanner (GE Medical Systems, USA) using an 8-channel head coil. Three-dimensional anatomical images of the entire brain were obtained parallel to the anterior–posterior commissure line with a T1-weighted structural image using a spoiled gradient echo sequence (3D SPGR, number of slices = 172, slice thickness = 1 mm, no interslice skip, matrix size = 256 × 256, field of view = 256 mm, FA = 8°, TE = 3 ms (N = 28 subjects) or 5 ms (N = 24 subjects), TR = 10 ms (N = 28 subjects) or 11 ms (N = 24 subjects), scan duratioN = 3 min 52 s).
9
MRI Imaging Acquisition Protocols
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T1-weighted images were acquired either at 1.5T (2004–2009, n = 745) or at 3T (2011–2019, n = 776). At 1.5T, images were acquired on a Siemens Magnetom Sonata scanner. At 3T, participants were scanned either on General Electric Signa HDxt scanner (n = 438) or a General Electric Discovery 750 scanner (n = 338). For details about the MRI acquisition parameters, see supplementary note 4 .
10
Multiparametric MRI Evaluation of Parotid Lesions
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The MRI data of patients were obtained from the picture archiving and communication system (PACS) of the First Affiliated Hospital of Zhengzhou University. Preoperative plain and contrast-enhanced MRI of the parotid gland was performed for each patient with parotid gland lesion in this study. MRI was performed on three 3.0 T MRI scanners with head/neck coil: a Skyra scanner (Siemens Healthineers, Germany), a Discovery 750 scanner (GE Healthcare, USA), and an Ingenia CX scanner (Philips Healthcare, Holland). The conventional scanning sequences including T1-weighted imaging (T1WI) in axial planes; T2-weighted imaging (T2WI) in axial, sagittal, and coronal planes, axial DWI, and post-contrast (Gadolinium, 0.1 mmol/kg) T1WI in axial, sagittal, and coronal planes were performed. The ADC maps were generated inline after the data acquisition and exported from the PACS workstation to a personal computer in DICOM format (30 (link)). A detailed overview of the MRI parameters is listed in Table 2
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