Human integrin αIIbβ3 was purchased from Enzyme Research Laboratories (South Bend, USA). Unless otherwise stated, all mentioned antibodies were bought from Biolegend (San Diego, USA). Dimyristoylphosphatidylglycerol (DMPG; 14:0 PG), dimyristolphosphatidylcholine (DMPC; 14:0 PC) and dioleoyl-glycero-phosphoethanolamine-N-carboxyfluorescein (PE CF) were obtained from Avanti Polar Lipids Inc. (Alabaster, USA). SM-2 biobeads were supplied by Bio-Rad (Munich, Germany). Unfractionated heparin (UFH), fondaparinux and quinine sulfate were purchased from Sigma-Aldrich (Steinheim, Germany). Protein concentration was determined by bicinchonic acid assay (BCA) kit with included protein microstandard (Sigma-Aldrich, Steinheim, Germany). Tris-Base, ethylenediaminetetraacetic acid (EDTA), bovine serum albumin and NaCl were bought from Sigma-Aldrich (Taufkirchen, Germany). CaCl2, MnCl2, Triton X-100 and methanol were purchased from Carl Roth GmbH (Karlsruhe, Germany). Sucrose and sodium dodecyl sulfate (SDS) were obtained from Merck KgaA (Darmstadt, Germany).
Human integrin αiibβ3
Manufactured by Enzyme Research
Sourced in United States
Human integrin αIIbβ3 is a cell surface receptor that plays a central role in platelet function and thrombosis. It is a heterodimeric glycoprotein composed of an alpha (αIIb) and a beta (β3) subunit. The core function of this receptor is to mediate platelet adhesion and aggregation, which is crucial for normal blood clotting and hemostasis.
Automatically generated - may contain errors
Lab products found in correlation
Cacl2, by Carl Roth (6 mentions)
Sm2 bio beads, by Bio-Rad (6 mentions)
Tris base, by Merck Group (6 mentions)
Sodium chloride (nacl), by Merck Group (6 mentions)
Triton x 100, by Carl Roth (6 mentions)
Sucrose, by Merck Group (6 mentions)
Methanol, by Carl Roth (6 mentions)
Sodium dodecyl sulfate (sds), by Merck Group (6 mentions)
Quinine sulfate, by Merck Group (3 mentions)
Mncl2, by Carl Roth (3 mentions)
Ethylenediaminetetraacetic acid edta, by Merck Group (3 mentions)
Bovine serum albumin (bsa), by Merck Group (3 mentions)
Fibrinogen, by Merck Group (3 mentions)
Iron 2 chloride tetrahydrate, by Thermo Fisher Scientific (3 mentions)
Iron 3 nitrate nonahydrate, by Thermo Fisher Scientific (3 mentions)
Iron 3 chloride hexahydrate, by ITW Reagents (3 mentions)
Ethylenediaminetetraacetic acid, by Merck Group (3 mentions)
1 2 dimyristoyl sn glycero 3 phosphocholine, by Avanti Polar Lipids (3 mentions)
2 protocols using human integrin αiibβ3
1
Integrin αIIbβ3 Binding Assay Protocol
2
Integrin αIIbβ3 Reconstitution and Characterization
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Iron(III) nitrate nonahydrate (Fe(NO 3 ) 3 •9H 2 O, >98%), and iron (II) chloride tetrahydrate (FeCl 2 •4H 2 O, 98%) were from Alfa Aesar. Iron(III) chloride hexahydrate (FeCl 3 •6H 2 O, >97%) was obtained from PanReac. Fibrinogen (lyophilized powder) was purchased from Merck KGaA (Darmstadt, Germany) with a purity of 98%. Dextran 6 with a molar mass of 6000 g mol -1 was obtained from Carl Roth GmbH + Co KG (Karlsruhe, Germany). Polyethylene glycol monomethylether phosphonic acid (PEG-PA; 1900 g mol -1 ) was purchased from Sikémia, France.
Human integrin αIIbβ3 was obtained from Enzyme Research Laboratories (South Bend, USA). 1,2-Dimyristoyl-snglycero-3-phosphoglycerol, (DMPG; 14:0 PG) and 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC; 14:0 PC) were purchased from Avanti Polar Lipids Inc. (Alabaster, USA). SM-2 biobeads were bought from Bio-Rad (Munich, Germany). Tris-Base, ethylenediaminetetraacetic acid (EDTA) and NaCl were supplied by Sigma-Aldrich (Taufkirchen, Germany). CaCl 2 , MnCl 2 , Triton X-100 and methanol were purchased from Carl Roth GmbH (Karlsruhe, Germany). Sucrose, phosphate buffered saline (PBS) and sodium dodecyl sulfate (SDS) were obtained from Merck KGaA (Darmstadt, Germany).
Human integrin αIIbβ3 was obtained from Enzyme Research Laboratories (South Bend, USA). 1,2-Dimyristoyl-snglycero-3-phosphoglycerol, (DMPG; 14:0 PG) and 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC; 14:0 PC) were purchased from Avanti Polar Lipids Inc. (Alabaster, USA). SM-2 biobeads were bought from Bio-Rad (Munich, Germany). Tris-Base, ethylenediaminetetraacetic acid (EDTA) and NaCl were supplied by Sigma-Aldrich (Taufkirchen, Germany). CaCl 2 , MnCl 2 , Triton X-100 and methanol were purchased from Carl Roth GmbH (Karlsruhe, Germany). Sucrose, phosphate buffered saline (PBS) and sodium dodecyl sulfate (SDS) were obtained from Merck KGaA (Darmstadt, Germany).
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