Caco-2 cells were obtained from American Type Culture Collection (Manassas, VA). Lovastatin was obtained from A.G. Scientific (San Diego, CA). Cell viability assay was conducted using the CellTiter 96® Non-Radioactive Cell Proliferation Assay (Promega, Madison, WI). pM vector was purchased from Clontech Laboratories, Inc. (Mountain View, CA). The reporter plasmid pFR-Luc was obtained from Agilent Technologies (La Jolla, CA). SGA360 and SGA315 were synthesized as previously described 17 (link). Primary antibodies used for immunoblot analysis are listed in Supplementary Table 1 . [1,2-3H(N)]-cholesterol was purchased from Perkin Elmer (Waltham, MA). Sodium taurocholate hydrate, 1-oleyl-rac-glycerol, and MG132 were obtained from Sigma Aldrich (St. Louis, MO). β-Naphthoflavone (BNF) was purchased from Indofine Chemical Company (Hillsborough, NJ). BAPTA/AM and AEBSF were purchased from Cayman Chemicals (Ann Arbor, MI). Lovastatin was purchased from A.G. Scientific (San Diego, CA).
Lovastatin
Manufactured by AG Scientific
Lovastatin is a laboratory product that functions as a cholesterol-lowering agent. It is a naturally occurring compound derived from the fungus Aspergillus terreus. Lovastatin inhibits the enzyme HMG-CoA reductase, which plays a key role in the biosynthesis of cholesterol in the body.
Automatically generated - may contain errors
Lab products found in correlation
Sodium taurocholate hydrate, by Merck Group (2 mentions)
Bapta am, by Cayman Chemical (2 mentions)
Pfr luc, by Agilent Technologies (2 mentions)
Pm vector, by Takara Bio (2 mentions)
1 oleyl rac glycerol, by Merck Group (2 mentions)
Mg132, by Merck Group (2 mentions)
Celltiter 96 non radioactive cell proliferation assay, by Promega (2 mentions)
Caco 2 cell, by American Type Culture Collection (2 mentions)
1 2 3h n cholesterol, by PerkinElmer (2 mentions)
2 protocols using lovastatin
1
Investigating Lovastatin's Effects on Caco-2 Cells
2
Investigating Lovastatin's Effects on Caco-2 Cells
Check if the same lab product or an alternative is used in the 5 most similar protocols
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Caco-2 cells were obtained from American Type Culture Collection (Manassas, VA). Lovastatin was obtained from A.G. Scientific (San Diego, CA). Cell viability assay was conducted using the CellTiter 96® Non-Radioactive Cell Proliferation Assay (Promega, Madison, WI). pM vector was purchased from Clontech Laboratories, Inc. (Mountain View, CA). The reporter plasmid pFR-Luc was obtained from Agilent Technologies (La Jolla, CA). SGA360 and SGA315 were synthesized as previously described 17 (link). Primary antibodies used for immunoblot analysis are listed in Supplementary Table 1 . [1,2-3H(N)]-cholesterol was purchased from Perkin Elmer (Waltham, MA). Sodium taurocholate hydrate, 1-oleyl-rac-glycerol, and MG132 were obtained from Sigma Aldrich (St. Louis, MO). β-Naphthoflavone (BNF) was purchased from Indofine Chemical Company (Hillsborough, NJ). BAPTA/AM and AEBSF were purchased from Cayman Chemicals (Ann Arbor, MI). Lovastatin was purchased from A.G. Scientific (San Diego, CA).
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