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Anti human cd8

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Anti-human CD8 is a monoclonal antibody used to detect the CD8 antigen, which is expressed on the surface of cytotoxic T cells. It is a core component of the T cell receptor complex and plays a crucial role in the immune response.

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Lab products found in correlation

Bond platform, by Leica (2 mentions) Benchmark ultra, by Leica (2 mentions) Anti human pd l1, by Agilent Technologies (2 mentions)

2 protocols using anti human cd8

1

Immuno-Histochemical Tissue Analysis

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For H&E staining, formalin-fixed, paraffin-embedded tissue cut at 4 microns and stained using the Tissue-Tek Prisma automated slide stainer. Immunostaining was performed on the Ventana Benchmark Ultra platform (CD3) and the Leica Bond platform (CD8, PD-L1). Antibodies used include anti-human CD3 (cat. no. 103A-76, Cell Marque), anti-human CD8 (cat. no. M7103, Dako) and anti-human PD-L1 (cat. no. 13684S, Cell Signaling Technology).
Yost K.E., Satpathy A.T., Wells D.K., Qi Y., Wang C., Kageyama R., McNamara K., Granja J.M., Sarin K.Y., Brown R.A., Gupta R.K., Curtis C., Bucktrout S.L., Davis M.M., Chang A.L, & Chang H.Y. (2019). Clonal replacement of tumor-specific T cells following PD-1 blockade. Nature medicine, 25(8), 1251-1259.
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2

Immuno-Histochemical Tissue Analysis

Check if the same lab product or an alternative is used in the 5 most similar protocols
For H&E staining, formalin-fixed, paraffin-embedded tissue cut at 4 microns and stained using the Tissue-Tek Prisma automated slide stainer. Immunostaining was performed on the Ventana Benchmark Ultra platform (CD3) and the Leica Bond platform (CD8, PD-L1). Antibodies used include anti-human CD3 (cat. no. 103A-76, Cell Marque), anti-human CD8 (cat. no. M7103, Dako) and anti-human PD-L1 (cat. no. 13684S, Cell Signaling Technology).
Yost K.E., Satpathy A.T., Wells D.K., Qi Y., Wang C., Kageyama R., McNamara K., Granja J.M., Sarin K.Y., Brown R.A., Gupta R.K., Curtis C., Bucktrout S.L., Davis M.M., Chang A.L, & Chang H.Y. (2019). Clonal replacement of tumor-specific T cells following PD-1 blockade. Nature medicine, 25(8), 1251-1259.
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