Diclofenac sodium salt dcf

Sodium salt of carboxymethylcellulose (CMC, M_w = 90 kDa, DS_COOH: 0.7) and poly(ethylene oxide) (PEG, M_w: 600 kDa) were purchased from Acros Organics (USA). 1,2,3,4-Butanetetracarboxylic acid (BTCA) was purchased from Merck (USA). Sodium hypophosphite monohydrate (SHP, NaPO₂H₂·H₂O) and diclofenac sodium salt (DCF) were purchased from Sigma-Aldrich (Germany). Quartz crystal microbalance (QCM) crystals coated with gold layer (QSX301) were purchased from LOT-Oriel, Germany. Milli-Q water from a Millipore water purification system (Millipore, USA; resistivity = 18.2 MΩ cm at 25 °C) was used for all sample preparation.

Titanium (IV) isopropoxide (TTIP, 97%, Sigma-Aldrich, St. Louis, MO, USA), acetylacetone (AcAc, ≥99%, Honeywell, Charlotte, NC, USA), absolute ethanol (EtOH, p.a., Grammol, Zagreb, Croatia), urea (99.5%, Sigma-Aldrich, St. Louis, MO, USA), graphene oxide water dispersion (0.4 wt.% concentration, Graphenea, Cambridge, MA, USA), ascorbic acid (p.a., Sigma-Aldrich, St. Louis, MO, USA), ciprofloxacin (CIP, 98%, Acros Organics, Waltham, MA, USA), diclofenac sodium salt (DCF, Sigma-Aldrich, St. Louis, MO, USA), salicylic acid (SA, p.a., Grammol, Zagreb, Croatia), p-Benzoquinone (≥99%, Sigma-Aldrich, St. Louis, MO, USA), formic acid (≥95%, Sigma-Aldrich, St. Louis, MO, USA) and methanol (≥99.9%, Sigma-Aldrich, St. Louis, MO, USA) were used as received without further purification. Deionized water of ultrapure quality (electrical conductivity of 0.055 µS∙cm⁻¹ at 25 °C) was used throughout the experiments.

Gellan gum sodium salt (Ge-Na) Kelcogel® CG-LA was purchased from Giusto Faravelli (Milano, Italy), soy phosphatidylcholine Phospholipon® 90G (P90G) was purchased from Lipoid GmbH (Ludwigshafen, Germany), cholesterol (CH) was purchased from Carlo Erba Reagents (Italy), diclofenac sodium salt (DCF) was purchased from Sigma Aldrich (Cornaredo, Italy). All other reagents were purchased from Sigma Aldrich (St. Louis, MI, USA). All products were used without further purification.