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E1l3n anti pd l1 antibody

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The E1L3N anti-PD-L1 antibody is a laboratory reagent used for the detection and analysis of the PD-L1 protein in various experimental and research applications. This antibody specifically binds to the PD-L1 protein, which plays a role in regulating the immune response.

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Automated method, by Leica (2 mentions)

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PD-L1 (184 citations) E1L3N (126 citations) Anti-PD-L1 (76 citations) Anti-PD-L1 antibody (22 citations) PD-L1 (E1L3N, (19 citations) PD-L1 antibody (11 citations) E1L3N antibody (7 citations) Anti-PD-L1 (E1L3N, (6 citations) PD-L1 antibody (E1L3N; (3 citations) Anti-PD-L1 monoclonal antibody (clone E1L3N; (2 citations)

2 protocols using e1l3n anti pd l1 antibody

1

PD-L1 Expression Quantification Protocol

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PDL1 IHC was performed using an automated method (Leica) and the E1L3N anti-PD-L1 antibody (Cell Signaling Technology) diluted to the 1/80th on 4 µm slides from the treatment-naïve diagnostic samples. The assay was performed using human amygdala as positive control, and IgG as isotype negative control. Proportion (percentage) of positive tumor cells (membranous staining) was recorded. A minimum of 100 tumor cells was needed for interpretation.
Giroux Leprieur E., Hélias-Rodzewicz Z., Takam Kamga P., Costantini A., Julie C., Corjon A., Dumenil C., Dumoulin J., Giraud V., Labrune S., Garinet S., Chinet T, & Emile J.F. (2020). Sequential ctDNA whole-exome sequencing in advanced lung adenocarcinoma with initial durable tumor response on immune checkpoint inhibitor and late progression. Journal for Immunotherapy of Cancer, 8(1), e000527.
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2

PD-L1 Immunohistochemistry for Tumor Samples

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PDL1 immunohistochemistry (IHC) was performed using an automated method (Leica) and the E1L3N anti-PD-L1 antibody (Cell Signalling Technology) diluted to the 1/80th on 4 μm-slides from the treatment-naïve diagnostic samples. The assay was performed using human amygdala as positive control, and IgG as isotype negative control. The IHC was considered as being positive if at least one tumour cell out of 100 analyzed tumor cells was positively stained.
Ouaknine Krief J., Helly de Tauriers P., Dumenil C., Neveux N., Dumoulin J., Giraud V., Labrune S., Tisserand J., Julie C., Emile J.F., Chinet T, & Giroux Leprieur E. (2019). Role of antibiotic use, plasma citrulline and blood microbiome in advanced non-small cell lung cancer patients treated with nivolumab. Journal for Immunotherapy of Cancer, 7, 176.
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