Acetic anhydride

Manufactured by Vetec

Sourced in Brazil

Acetic anhydride is a colorless, volatile liquid that is commonly used as a reagent in organic synthesis. It is a key ingredient in the production of various pharmaceutical and chemical intermediates. Acetic anhydride has a high degree of reactivity and is often employed in acetylation reactions to introduce acetyl groups into organic molecules.

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Lab products found in correlation

Sodium hydroxide (naoh), by Vetec (2 mentions) Acetic acid, by Vetec (2 mentions) Dichloromethane, by Vetec (1 mentions) Ethyl iodide, by Merck Group (1 mentions) Benzoyl peroxide, by Merck Group (1 mentions) Ketoconazole, by Vetec (1 mentions) Polyvinyl alcohol (pva), by Merck Group (1 mentions) Methyl methacrylate, by Merck Group (1 mentions) Hydrochloric acid (hcl), by Vetec (1 mentions) Sulfuric acid, by Vetec (1 mentions) Sodium bicarbonate, by Vetec (1 mentions) Pyridine, by Vetec (1 mentions) Succinic anhydride, by Vetec (1 mentions) Ethanol, by Vetec (1 mentions) Riboflavin, by HiMedia (1 mentions) Acetone, by Vetec (1 mentions)

3 protocols using acetic anhydride

Ketoconazole-Loaded Polymeric Films

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The reagents used for the films and incorporation with ketoconazole were sodium hydroxide (NaOH), acetic anhydride (CH₃COOCOCH₃), acetic acid (CH₃COOH), hydrochloric acid (HCl), sodium bicarbonate (NaHCO₃), sulfuric acid (H₂SO₄), commercial ketoconazole, and dichloromethane (CH₂Cl₂), purchased from Vetec. Poly (vinyl alcohol) (average mol wt 30,000–70,000), ethyl iodide (CH₂CH₃I), chloride sodium (NaCl), benzoyl peroxide, methyl methacrylate (MMA), and distilled water were purchased from Sigma Aldrich. The copolymers PMMA-g-PEG 4000 and derivatives were synthesized by our research group and published in scientific journals [19 (link),20 (link),21 (link),22 (link),23 (link)].

Reynaldo J.R., Novack K.M., Sousa L.R., Vieira P.M., Amparo T.R., de Souza G.H., Teixeira L.F., Barboza A.P., Neves B.R., Alvarenga M.E., Martins F.T, & dos Santos V.M. (2022). Evaluation of Anti-Candida albicans Activity and Release of Ketoconazole in PMMA-G-PEG 4000 Films. International Journal of Molecular Sciences, 23(18), 10775.

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Enzymatic Esterification of Clove Oil

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Clove essential oil (Caryoplyllus aromaticus) was purchased from Viafarma (São Paulo-Brazil) and used as substrate for enzymatic esterification. The main characteristics of the oil are presented in Table 1. Acetic anhydride (Vetec, 97% purity) was also used as substrate and the commercial lipase from Candida antarctica (Novozym 435) immobilized on a macroporous anionic resin was donated by Novozymes Brazil (Araucária, PR, Brazil)was used as catalyst. Eugenyl acetate from Sigma-Aldrich was used as standard for product confirmation.

Cansian R.L., Vanin A.B., Orlando T., Piazza S.P., Puton B.M., Cardoso R.I., Gonçalves I.L., Honaiser T.C., Paroul N, & Oliveira D. (2017). Toxicity of clove essential oil and its ester eugenyl acetate against Artemia salina. Brazilian journal of biology = Revista brasleira de biologia, 77(1).

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Microcrystalline Cellulose and Azo Dye Synthesis

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Microcrystalline cellulose and sulfanilic acid (≥99.0%) were purchased from respectively, Brazil) . Riboflavin (Fig. 1a), succinic anhydride, acetic anhydride, acetic acid, pyridine, sodium hydroxide, ethanol, acetone, and methylene chloride were purchased from Vetec (Brazil). Hydrochloric acid, diethyl ether, N,Ndimethylformamide (DMF), and dimethylsulfoxide (DMSO) were purchased from Synth (Brazil). Remazol Golden Yellow RNL (RGY-RNL, C 16 H 18 N 4 O 10 S 3 Na 2 , Fig. 1a) azo dye was kindly provided by a local textile industry and used without further purification. Yeast extract containing 50 g/g of Riboflavin was purchased from Himedia.

Martins L.R., Baêta B.E.L., Gurgel L.V.A., de Aquino S.F, & Gil L.F. (2015). Application of cellulose-immobilized riboflavin as a redox mediator for anaerobic degradation of a model azo dye Remazol Golden Yellow RNL. Industrial Crops & Products., 65.

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