All rats underwent a protocol consisting of neurophysiological recordings and behavioral tasks. Recordings were started at a fixed time, timed after each behavioral intervention. Neurophysiological signals were amplified, digitized continuously at 20 kHz using a headstage directly attached to the probe (RHD2000; Intan Technologies), and stored for offline analysis with 16-bit format. Data were analyzed using MATLAB (MathWorks) and visualized using Neuroscope.
Neuroscope
Manufactured by MathWorks
The Neuroscope is a laboratory instrument designed for the recording and analysis of neural signals. It provides the capability to capture and process electrical activity from the nervous system. The Neuroscope is a tool used by researchers and scientists in the field of neuroscience and neurophysiology.
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Lab products found in correlation
2 protocols using neuroscope
1
Neurophysiological Recordings and Behavioral Tasks
2
Multimodal Analysis of Neonatal Neural Dynamics
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All in vivo data were analyzed and visualized in MATLAB (Mathworks) or NeuroScope (Hazan et al., 2006) (link). LFPs were downsampled to 1.25 kHz from raw traces; current source densities (CSDs) were built from the 2 nd spatial derivative of 1-200 Hz filtered LFPs.
Multitaper spectrograms were computed using the Chronux toolbox (http://chronux.org/); for visualization wavelets were also used.
In neonates, sharp waves (SW) were considered to be the point of maximum negativity in deep hippocampus after automatically detecting high variance across CSD traces; SW amplitudes were quantified by max. peak to min. trough in the LFP. Hippocampal beta oscillations (HBOs) with maximum CSD amplitudes in apical dendritic layers of CA1 and spindle bursts in the primary visual cortex were manually detected by an experimenter who was blinded to the experimental group, and verified by independent observers.
Multitaper spectrograms were computed using the Chronux toolbox (http://chronux.org/); for visualization wavelets were also used.
In neonates, sharp waves (SW) were considered to be the point of maximum negativity in deep hippocampus after automatically detecting high variance across CSD traces; SW amplitudes were quantified by max. peak to min. trough in the LFP. Hippocampal beta oscillations (HBOs) with maximum CSD amplitudes in apical dendritic layers of CA1 and spindle bursts in the primary visual cortex were manually detected by an experimenter who was blinded to the experimental group, and verified by independent observers.
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