Poly l lactide plla

Poly-L-lactide (PLLA) (Corbion, Amsterdam, The Netherlands) was used to prepare films with a thickness of 0.7 µm. Chloroform (>98%, Macron Fine Chemicals, Gliwice, Poland), methanol (MeOH, 98%, Panreac, Damrstadt, Germany), acetic acid (>98%, Sigma Aldrich, Steinheim am Albuch, Germany), hydrochloric acid (HCl, 37%, Panreac, Darmstadt, Germany), and Milli-Q water were used as solvents. Sodium hydroxide (99%, Panreac, Darmstadt, Germany), sodium hydrogen carbonate (NaHCO₃, 99%, Merck, Darmstadt, Germany), sodium carbonate (Na₂CO₃, 98%, Panreac, Darmstadt, Germany), N-(3-dimethylaminopropyl)-N-ethylcarbodiimide hydrochloride (EDC·HCl, 98%, Sigma Aldrich, Beijing, China), N-hydroxysuccinimide (NHS, 98%, Sigma Aldrich, St. Louis, MO, USA), propiolic acid (95%, Sigma Aldrich, Poland), (S)-(-)-tryptophan (98%, Panreac, Darmstadt, Germany), and amoxicillin (98%, Sigma Aldrich, St. Louis, MO, USA) were used as reagents for the PLLA surface preactivation and functionalization.

Poly-l-lactide (PLLA) (Corbion, Amsterdam, The Netherlands) was used to prepare membranes. Chloroform (>98% Macron Fine Chemicals, Gliwice, Poland), tert-butanol (^tBuOH), ethanol (EtOH), methanol (MeOH, 98%), acetonitrinile (99%, Panreac, Darmstadt, Germany), dichloromethane (CH₂Cl₂, 98%, Macron Fine Chemicals), toluene (99%, Sigma Aldrich, St. Louis, MO, USA), N,N-dimethylformamide (DMF, 99%, Macron Fine Chemicals), acetic acid (Sigma Aldrich), deuterated chloroform (99.8% Sigma Aldrich) and Milli Q water were used as a solvents. Sodium hydroxide (99%, Panreac), N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (EDC·HCl, 98%), N-hydroxysuccinimide (NHS, 98%), triethylamine (<99.5%), propargylamine (97.5%), 3-bromopropylamine hydrobromide (98%), sodium azide (NaN₃, 99.5%), copper (II) sulphate pentahydrate (Cu₂SO₄·5H₂O, 98%), sodium ascorbate (98%), sodium sulphate anhydrous (Na₂SO₄, 96%, Panreac), N,N-diisopropylethylamine (DIPEA, 99%), N,N′-dicyclohexylcarbodiimide (DCC, 99%), 1-hydroxybenzotriazole hydrate (HOBT, 97%), O-toluidine blue (TBO, dye content 80%), dansyl chloride (>99%), indomethacin (>99%), thionyl chloride (>99%) from Sigma Aldrich were used as reactants. All the synthesized products spectra are summarized in Supplementary Information (Schemes S1–S4, Figures S1–S8).