Preoperative IMRT was performed within 3 days after completion of all preoperative investigations and careful evaluation by the radiation clinicians. The gross tumor volume was defined as the tumor volume that was enhanced in the arterial phase on preoperative CE-MRI scans using the Pinnacle3 9.0 treatment planning systems (Philips Healthcare, Andover, MA, USA). The clinical tumor volume (CTV) was drawn by adding 5–10 mm to the gross tumor volume. The planning target volume (PTV) was generated by adding 5mm in the anterior–posterior and left–right directions and 10mm in the cranial–caudal direction from the CTV considering respiratory liver motion and set-up errors. The prescription dose to 95% of the PTV was planned at 50-60 Gy in 25-30 fractions over 5-6 weeks. The final prescription dose was determined according to dose constraints for organs at risk.
Pinnacle3 9
Manufactured by Philips
Sourced in United States, Sweden
The Pinnacle3 9.0 is a laboratory equipment product manufactured by Philips. It is designed to perform specific laboratory functions, but a detailed and unbiased description of its core function cannot be provided without the risk of extrapolation or interpretation.
Automatically generated - may contain errors
Lab products found in correlation
2 protocols using pinnacle3 9
1
Preoperative IMRT for Liver Tumors
2
Automated and Manual Contouring Protocol for Anatomical Structures
Check if the same lab product or an alternative is used in the 5 most similar protocols
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A contouring protocol set image window levels to Window/Level=400/800 HU and described allowable techniques/tools. All eight rectangular prisms were auto-contoured using auto-threshold at recommended threshold values or other automated tools (e.g. Oncentra's magic-wand tool). Rectangular prisms 1, 4 and 8 (Supplementary Fig. 1.) were manually contoured. Bounding boxes in auto-contouring and zoom functions were allowed. The breast contour was manually delineated; allowing interpolation between slices and/or copy to next slice. The triangular prism and cylinder were both delineated using automated tools (such as auto-threshold) and manually. All eight observers were blind to others contours.
The TPSs used for contouring were; Eclipse Planning System 11.0.64 (Varian Medical Systems, Palo Alto Canada): 2 sites, Oncentra (Elekta, Stockholm Sweden): 2 sites, Pinnacle 3 9.0 (Philips, Netherlands): 2 sites, and FocalSim 4.80.01 (Elekta, Stockholm Sweden): 2 sites. These contours were then exported and collated in CERR.
The TPSs used for contouring were; Eclipse Planning System 11.0.64 (Varian Medical Systems, Palo Alto Canada): 2 sites, Oncentra (Elekta, Stockholm Sweden): 2 sites, Pinnacle 3 9.0 (Philips, Netherlands): 2 sites, and FocalSim 4.80.01 (Elekta, Stockholm Sweden): 2 sites. These contours were then exported and collated in CERR.
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