24 s hydroxycholesterol

Manufactured by Avanti Polar Lipids

Sourced in United States

24(S)-hydroxycholesterol is a naturally occurring oxysterol compound. It is the primary form of hydroxycholesterol found in the brain and serves as a key intermediate in the biosynthesis of neurosteroids.

Automatically generated - may contain errors

Lab products found in correlation

25 hydroxycholesterol, by Avanti Polar Lipids (3 mentions) 25 hydroxycholesterol d6, by Avanti Polar Lipids (3 mentions) 27 hydroxycholesterol, by Avanti Polar Lipids (2 mentions) 27 hydroxycholesterol d6, by Avanti Polar Lipids (2 mentions) Hexane, by Thermo Fisher Scientific (2 mentions) Formic acid, by Thermo Fisher Scientific (2 mentions) Methanol, by Thermo Fisher Scientific (2 mentions) Isopropanol, by Thermo Fisher Scientific (2 mentions) Authentic standard 7 keto cholesterol, by Cayman Chemical (2 mentions) Butylacetate, by Thermo Fisher Scientific (2 mentions) Butylated hydroxytoluene bht, by Merck Group (2 mentions) Deuterated 24 r s hydroxycholesterol d7, by Avanti Polar Lipids (2 mentions) Picolinic acid, by Merck Group (1 mentions) Ethanol, by Avantor (1 mentions) Hexane, by Avantor (1 mentions) 4 dimethylaminopyridine, by Merck Group (1 mentions) Trimethylamine, by Merck Group (1 mentions) 2 propanol, by Avantor (1 mentions) 2 methyl 6 nitrobenzoic anhydride, by Merck Group (1 mentions) Hplc grade methanol, by Avantor (1 mentions)

Close spelling variants of this product

24(R/S)-hydroxycholesterol-d6 (2 citations) Deuterated (24(R/S)-hydroxycholesterol-d7 (2 citations)

3 protocols using 24 s hydroxycholesterol

Quantification of Oxysterols by LC-MS/MS

Check if the same lab product or an alternative is used in the 5 most similar protocols

24S-Hydroxycholesterol [cholest-5-ene-3-beta,24S-diol], 25-hydroxycholesterol [cholest-5-ene-3-beta,25-diol], 27-hydroxycholesterol [cholest-5-ene-3beta,27-diol], 24(R/S)-hydroxycholesterol-d6 [26, 26, 26, 27, 27, 27-hexadeuterocholest-5-ene-3 beta,24-diol], 25-hydroxycholesterol-d6 [26, 26, 26, 27, 27, 27-hexadeuterocholest-5-ene-3 beta,25-diol] and 27-hydroxycholesterol-d6 [25, 26, 26, 26, 27, 27-hexadeuterocholest-5-ene-3 beta,27-diol] were obtained from Avanti Polar Lipids (Alabama, USA). 2-methyl-6-nitrobenzoic anhydride, 4-dimethylamino pyridine, picolinic acid, pyridine and trimethylamine were purchased from Sigma Aldrich Co. (St. Louis, USA). Phosphoric acid and potassium hydroxide were provided by Junsei (Tokyo, Japan). Distilled water was purified using a Milli-Q purification system (Millipore, Massachusetts, USA). High performance liquid chromatography (HPLC)-grade m ethanol, ethanol, hexane and 2-propanol were purchased from Burdick & Jackson (Ulsan, Korea).

Cha E., Lee K.M., Park K.D., Park K.S., Lee K.W., Kim S.M, & Lee J. (2016). Hydroxycholesterol Levels in the Serum and Cerebrospinal Fluid of Patients with Neuromyelitis Optica Revealed by LC-Ag+CIS/MS/MS and LC-ESI/MS/MS with Picolinic Derivatization: Increased Levels and Association with Disability during Acute Attack. PLoS ONE, 11(12), e0167819.

+ Open protocol

+ Expand

Quantification of Oxysterol Biomarkers

Check if the same lab product or an alternative is used in the 5 most similar protocols

Authentic standards (24(S)-hydroxycholesterol, 27-hydroxycholesterol, 25-hydroxycholesterol, 7ß-hydroxycholesterol) and deuterated (24(R/S)-hydroxycholesterol-d7, 25-hydroxycholesterol-d6, 27-hydroxycholesterol-d6, 7ß-hydroxycholesterol-d7, 7-ketocholesterol-d7) were purchased from Avanti polar lipids, Alabama. Authentic standard 7 keto cholesterol was purchased from Cayman chemicals, MI, USA. Butylacetate, hexane, isopropanol, methanol and formic acid (HPLC/MS grade) were purchased from Fisher Scientific, UK. Butylated hydroxytoluene (BHT) and Discovery DSC18 cartridges were from Sigma-Aldrich, UK. Oasis HLB Prime and Oasis HLB cartridges were purchased from Waters.

Dias I.H., Milic I., Lip G.Y., Devitt A., Polidori M.C, & Griffiths H.R. (2018). Simvastatin reduces circulating oxysterol levels in men with hypercholesterolaemia. Redox Biology, 16, 139-145.

+ Open protocol

+ Expand

Quantitative Analysis of Oxysterols

Check if the same lab product or an alternative is used in the 5 most similar protocols

Authentic standards (24(S)-hydroxycholesterol, 26-hydroxycholesterol, 25-hydroxycholesterol, 7β-hydroxycholesterol) and deuterated (24(R/S)-hydroxycholesterol-d7, 25-hydroxycholesterol-d6, 26-hydroxycholesterol-d6, 7β-hydroxycholesterol-d7, 7-ketocholesterol-d5) were purchased from Avanti polar lipids, Alabama. Authentic standard 7 keto cholesterol was purchased from Cayman chemicals, MI, USA. Butyl acetate, hexane, isopropanol, methanol, and formic acid (HPLC/MS grade) were purchased from Fisher Scientific, UK. Butylated hydroxytoluene (BHT) was from Sigma-Aldrich, UK. Oasis HLB Prime cartridges were purchased from Waters.

Dias I.H., Shokr H., Shephard F, & Chakrabarti L. (2022). Oxysterols and Oxysterol Sulfates in Alzheimer’s Disease Brain and Cerebrospinal Fluid. Journal of Alzheimer's Disease, 87(4), 1527-1536.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!