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Oxybutynin

Manufactured by Merck Group
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Sourced in Slovakia

Oxybutynin is a pharmaceutical product manufactured by Merck Group. It is a synthetic compound used in various laboratory applications. The core function of Oxybutynin is to serve as a research tool for scientific investigations, but a detailed description cannot be provided while maintaining an unbiased and factual approach.

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Lab products found in correlation

Dimethyl sulfoxide (dmso), by Merck Group (1 mentions) Diltiazem hydrochloride, by Merck Group (1 mentions) Skf96365, by Bio-Techne (1 mentions) 2 apb, by Bio-Techne (1 mentions) Mirabegron, by Astellas Pharma (1 mentions)

Spelling variants of this product

Oxybutynin chloride (3 citations)

2 protocols using oxybutynin

1

Oxybutynin and Eserine Effects on Rats

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Experiments were performed in nine male rats (311.1 ± 9.0 g, 280–360 g) and 10 females (268.0 ± 5.5 g, 240–290 g). This protocol consisted of (i) ACSF; (ii) 100 μM oxybutynin (MW: 393.95 g/mol, catalogue number: O2881, Sigma); (iii) 100 μM oxybutynin co-applied with 100 μM eserine. oxybutynin is a muscarinic receptor antagonist with affinities across the range of muscarinic receptor subtypes21 (link) and a component of effective OSA pharmacotherapy11 (link),15 (link),16 (link),22 (link).
Niakani S., Liu H., Liu W.Y, & Horner R.L. (2022). Differential pharmacological and sex-specific effects of antimuscarinic agents at the hypoglossal motor nucleus in vivo in rats. Scientific Reports, 12, 14896.
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2

Solubility of Pharmaceutical Compounds

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Oxybutynin, dimethyl sulfoxide (DMSO) and diltiazem hydrochloride were obtained from Sigma-Aldrich (Lambda life, Slovakia). 2APB, 3-fluoropyride-4-carboxylic acid and SKF96365 were purchased from Tocris Bioscience (USA) and mirabegron was purchased from Astellas Pharma Inc. (Japan). All chemicals were dissolved in aqua pro injection except from 2APB, which was soluble in 10% DMSO.
Luptak J., Kocmalova M., Franova S., Sutovsky J., Grendar M., Svihra J., Kliment J S.r., Dusenka R, & Sutovska M. (2018). Involvement of calcium regulating ion channels in contractility of human isolated urinary bladder. General physiology and biophysics, 37(4).
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