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Octabenzone

Manufactured by Merck Group
Sourced in United States, Canada

Octabenzone is a UV filter compound used in personal care products, such as sunscreens, to absorb ultraviolet radiation and protect the skin from sun damage. It is a solid, crystalline substance with a melting point of approximately 54°C.

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2 protocols using octabenzone

1

Polyethylene Nanocomposite Formulation

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High-purity surrogates (biphenyl, benzophenone, methyl stearate and octabenzone) were provided by Sigma-Aldrich (Saint-Louis, MO, USA). Linear low density polyethylene (grade LL 1002YB, melt flow index of 2.0 g/10 min, density of 0.918 g·cm−3), supplied by Exxon Mobil Chemical (Irving, TX, USA), was chosen as the polymer matrix (labelled “PE” in the present work). Clay was provided as a 40%-loaded masterbatch also based on linear low density polyethylene. The organically modified montmorillonite was Nanomer I44P (containing 38% dimethyl dialkyl (C14-18) Ammonium as checked by thermogravimetric analyses) from Nanocor (Hoffman Estates, IL, USA). The mineral content of the masterbatch was measured at 23.5% using TGA.
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2

Quantification of Phthalates and Other Compounds

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Standards of Octabenzone, and 2,4-Di-Tert-butylphenol (DTBP) were purchased from Sigma (Oakville, ON, Canada). Dimethyl phthalate (DMP), Diethyl phthalate (DEP), Diisobutyl phthalate (DIBP), Di-n-butyl phthalate (DBP), Butyl benzyl phthalate (BBP), Dicyclohexyl phthalate (DCHP) and Di(2-ethylhexyl) phthalate (DEHP) were obtained from Scientific Polymer (New York, USA). All solvents, Dichloromethane, Acetone, Toluene, Isopropyl alcohol and water were HPLC plus grade. Solvents as well as Sodium chloride (ACS grade) were obtained from Sigma. Sodium sulfate Anhydrous (ACS grade) was supplied by Fisher Scientific (Ottawa, ON, Canada). Chemical standards are listed in Table 1 with their QC parameters.

List of chemical standards and QC parameters.

Table 1
Chemical nameCAS no.Retention time (min)Quantifier ion (m/z)Qualifier ions (m/z)LQ* (μg/L)
2,4-Di-Tert-butylphenol96-76-47.98191206, 19211
Butyl benzyl phthalate85-68-718.78149206, 91592
Dicyclohexyl phthalate84-61-720.37249149, 16781
Di(2-ethylhexyl) phthalate117-81-720.42279149, 167752
Octabenzone1843-05-622.97326213, 32531

LQ was calculated as 10 times S/N ratio for compounds not detected in the blank sample (1) and as mean of blank plus 10 times SD of blank signal for compounds detected in the blank sample (2).

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