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Advia centaur xp platform

Manufactured by Siemens
Sourced in Germany

The ADVIA Centaur XP platform is a fully automated immunoassay system designed for in vitro diagnostic testing. It is capable of performing a wide range of immunoassays, including tests for hormones, cardiac markers, and infectious diseases. The platform utilizes chemiluminescent technology to provide reliable and accurate results.

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2 protocols using advia centaur xp platform

1

Comprehensive Data Extraction and Analysis

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Two investigators (PD and BQ) independently extracted data including demographic data, comorbidities, laboratory data and outcome data from all of the included studies using a standardized data collection form for analysis and, all data of the patients were checked by two investigators (PD and LY) independently to verify data accuracy.
The hematological parameters (including red blood cell count, platelet count, hemoglobin, white blood cell, lymphocyte count, neutrophil count, and monocyte count) were determined using XN-9000 Hematology Analyzer (Sysmex, Kobe, Japan). The ADVIA 2400 Clinical Chemistry System (Siemens, Erlangen, Germany) was used to measure the albumin, alanine aminotransferase, aspartate aminotransferase, creatine kinase, creatinine (Cr), lactate dehydrogenase, total bilirubin, and blood urea nitrogen. The levels of cTnI-ultra, CK-MB, MYO, and NT-proBNP was measured on a ADVIA Centaur XP platform (Siemens, Erlangen, Germany). Coagulation parameters including plasma D-dimer and prothrombin time were measured by CA7000 Coagulation Analyzer (Sysmex, Kobe, Japan).
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2

Evaluating SARS-CoV-2 Antibody Assays

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We evaluated the performance of the following fully automated CLIA tests on high throughput random access analyzers widely available in medical laboratories: Roche Elecsys Anti-SARS-CoV-2 assay on the Cobas e602 platform (Roche Diagnostics, Rotkreuz, Switzerland), Abbott SARS-CoV-2 IgG assay on the Architect i2000SR platform (Abbott Laboratories Abbott Park, IL, USA), Siemens SARS-CoV-2 total (COV2T) and SARS-CoV-2 IgG (COV2G) on the Advia Centaur XP platform (Siemens, Munich, Germany). All samples were processed according to the manufacturers' procedures with the specified controls and calibrators by trained laboratory staff. Test characteristics given in the manufacturers' product information are summarized in Supplementary Table S1. Precision was evaluated by repeatedly measuring the positive controls of the respective assays (Supplementary Results).
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