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2 protocols using benzophenone

1

Synthesis of Fourth-Generation Phenylazomethine Dendrons

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pyDPAG4 and DPAG4 were synthesized by a convergent method. The fourth-generation phenylazomethine dendrons were connected to the core molecules. The detailed procedures are described in previous reports42 (link),43 (link). AlCl3 (ultra dry) was purchased from Alfa Aesar, a Johnson Matthey Company. Dehydrated THF (stabilizer-free) was obtained from Kanto Chemicals. Sodium metal, benzophenone and tetrabutylammonium hexafluorophosphate were obtained from Wako Pure Chemical Industries, Ltd. and TCI Co., Ltd.
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2

Evaluation of Phototoxic Chemicals

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Twenty phototoxic chemicals and 10 non-phototoxic chemicals were evaluated, including 6 drugs, 8 antimicrobials, 6 fragrances, 6 UV absorbers, and 4 other chemicals. Amiodarone HCl (1), anthracene (7), chlorpromazine HCl (9), 5-methoxypsoralen (15), 8-methox-ypsoralen (16), 6-methylcoumarin (17), ofloxacin (18) , hexachlorophene (21), ethylhexyl dimethyl p-aminobenzoate (23), chlorhexidine dihydrochloride (24), sodium lauryl sulfate (27), p-aminobenzoic acid (28), sulisobenzone (29), and lactic acid (30) were purchased from Sigma-Aldrich Japan (Tokyo, Japan). Rose bengal (2), bithionol (4), 3,3'4,5 tetrachlorosalicylanilide (5), fenofibrate (6), benzophenone (11), ketoprofen (13), methyl n-methylantranilate ( 14), and norfloxacin (19) were purchased from Wako Pure Chemical Industries (Osaka, Japan). 3,4',5-Tribromosalicylanilide (3), musk ambrette (8), promethazine (10), musk xylene (12), protoporphyrin IX, disodium (20), 2-octyl salicylate ( 22), 2-octyl methacrylate (25), and penicillin G (26) were purchased from Tokyo Chemical Industry (Tokyo, Japan).
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