Possible flat-type dysplastic lesions were detected based on the color change using regular white-light colonoscopy (CF-Q240I, H290AI or PCF-Q260AI, Q260AZI, H290I; Olympus, Tokyo, Japan). Identified lesions were observed following 0.2–0.4 % indigo carmine dye spraying. To further determine whether these areas were dysplastic or non-neoplastic, subsequent magnifying colonoscopy (CF-H260AZI, HQ290I or PCF-Q260AZI, H290AZI; Olympus) using NBI and/or 0.05 % crystal violet staining were performed to identify their lines of demarcation. The endoscopic morphology was classified in accordance with the SCENIC international consensus statement. Briefly, flat lesions were defined as tumors without elevation or depression relative to the surrounding mucosa and could be detected only by their color change. Classifications were determined retrospectively after thorough discussion by two expert endoscopists (YI and MN) based on the detailed information provided by reporting endoscopists. The endoscopic disease activity was assessed by trained colonoscopists in accordance with the Mayo endoscopic score.
Cf q240i
Manufactured by Olympus
Sourced in Japan
The CF-Q240I is a compact and versatile laboratory equipment designed for a variety of scientific applications. It features a high-resolution camera and advanced imaging capabilities, enabling clear and detailed visualization of samples. The device is equipped with user-friendly controls and interfaces, allowing for efficient operation and seamless integration into laboratory workflows.
Automatically generated - may contain errors
3 protocols using cf q240i
1
Detecting Dysplastic Lesions in Colonoscopy
2
Colonoscopy Adenoma Surveillance: BMI and Metformin
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All examinations were conducted by 6 experienced endoscopists using a standard colonoscope (CF-Q240I and CF-Q260AI; Olympus, Tokyo, Japan). All adenomas detected during screening colonoscopy were removed in all patients. Even though the interval between follow-up colonoscopies varied, surveillance colonoscopy was performed at least once. The time of occurrence, number and size of adenomas, and biopsy outcomes were examined. Adenoma size was measured using biopsy forceps during colonoscopy. Advanced adenomas were defined as an adenoma larger than 10 mm or an adenoma of any size with a villous or tubulovillous component, or high-grade dysplasia. Hyperplastic or inflammatory polyps were discriminated by the absence of adenomatous polyps. The BMI of patients was classified into normal (≤25 kg/m2), overweight (25-30 kg/m2), and obese (≥30 kg/m2). Based on medical records, patients who used metformin for more than 6 months at minimum were categorized into the metformin group. This study was performed after gaining approval from the Institutional Review Board (IRB) of the Dankook University Hospital.
3
Endoscopic Evaluation of Ulcerative Colitis
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Colonoscopy was performed by five expert endoscopists who had conducted at least 2000 CSs using standard CS tools (PCF-Q260, CF-HQ290 I, CF-H260 AZI, CF-Q240 I; Olympus, Tokyo, Japan) before conducting the study procedures. A polyethylene glycol-based bowel preparation was provided to the patients. For patients with severe UC, CS was performed without bowel preparation to avoid the risk of perforation. Six colonic segments and the rectum were examined by CS.
In each segment, disease activity was assessed according to Matts' endoscopic classification (CS grades1-4) as follows: grade 1 = remission; grade 2 = mild activity; grade 3 = moderate activity; grade 4 = severe activity (Hozumi et al. 2013; Matts 1961; Walsh et al. 2014 ) (Fig. 2). The physicians performing the endo scopic examinations were aware of the UC diagnosis but were blinded to the results of the US examinations. First, CS grade was assessed at each examining facility. Next, still images were sent to and re-assessed at the central facility.
Three endoscopists (K.K, R.O. and T.K) affiliated with the central facility who had more than 4 y of experience in performing CS interpreted CS grading by consensus. They were also blinded to the patients' clinical information.
In each segment, disease activity was assessed according to Matts' endoscopic classification (CS grades1-4) as follows: grade 1 = remission; grade 2 = mild activity; grade 3 = moderate activity; grade 4 = severe activity (Hozumi et al. 2013; Matts 1961; Walsh et al. 2014 ) (Fig. 2). The physicians performing the endo scopic examinations were aware of the UC diagnosis but were blinded to the results of the US examinations. First, CS grade was assessed at each examining facility. Next, still images were sent to and re-assessed at the central facility.
Three endoscopists (K.K, R.O. and T.K) affiliated with the central facility who had more than 4 y of experience in performing CS interpreted CS grading by consensus. They were also blinded to the patients' clinical information.
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