Donepezil hydrochloride tablets
Donepezil hydrochloride tablets are a prescription medication used to treat the symptoms of Alzheimer's disease. The active ingredient, donepezil hydrochloride, works by inhibiting the breakdown of acetylcholine, a neurotransmitter important for cognitive function. This medication is available in various dosage strengths and is typically taken once daily.
Lab products found in correlation
7 protocols using donepezil hydrochloride tablets
Neuroprotective Compounds Evaluation
Evaluation of (-)-SCR1693 Efficacy in Rats
Acupuncture Intervention for Alzheimer's
In the MA group, the mice were immobilized in mouse bags. MA on Baihui (GV20) and Yintang (GV29) was applied for 20 min, with transverse puncturing at a depth of 2-3 mm; then, the mice were pricked at Shuigou (GV26) with disposable sterile acupuncture needles (0.25 mm × 13 mm) (Beijing Zhongyan Taihe Medicine Company, Ltd). During the MA on Baihui (GV20) and Yintang (GV29), twirling manipulation was applied every 5 min and lasted 15 s each time. Each needle was rotated bidirectionally within 90° at a speed of 180°/s. The selection of the acupoints was based on findings from our previous studies [23 (link), 24 (link)]. For the M group, donepezil hydrochloride tablets (Eisai China Inc., H20050978) were crushed and dissolved in distilled water and were delivered to mice by oral gavage at a dose of 0.65 μg/g [25 (link)]. The above treatments were administered once a day for 15 consecutive days, but no treatment was carried out in the N or AD groups. The mice in the AD, N, and M groups received the same 20-min restriction as the MA group.
Donepezil Hydrochloride Alleviates Aβ25-35-Induced Neurodegeneration
Electroacupuncture Alleviates Alzheimer's in Mice
Electroacupuncture for Alzheimer's Disease
Acupuncture Intervention in Alzheimer's Disease
In the MA group, the mice were immobilized in mouse bags. MA on Baihui (GV20) and Yintang (GV29) was applied for 20 min, with transverse puncturing at a depth of 2–3 mm. The disposable sterile acupuncture needles (0.25 mm × 13 mm) (Beijing Zhongyan Taihe Medicine Company, Ltd.) were used. During the MA on Baihui (GV20) and Yintang (GV29), twirling manipulation was applied every 5 min and lasted 15 s each time. Each needle was rotated bidirectionally within 90° at a speed of 180°/s. For the M group, donepezil hydrochloride tablets (Eisai China, Inc., H20050978) were crushed and dissolved in distilled water and were delivered to mice by oral gavage at a dose of 0.65 μg/g (Geerts et al., 2005 (link)). The above treatments were administered once a day for 15 consecutive days, with no treatment of the N or AD groups. The mice in the N, AD, and M groups received the same 20 min restriction as the MA group. The duration of MA and selection of the acupoints was based on findings from our previous studies (Jiang et al., 2015 (link), 2016 (link), 2018 (link); Cao et al., 2017 (link); Ding et al., 2017 (link)). The above intervention lasted throughout the Morris water maze test period.
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