Niopam 370

Manufactured by Bracco

Sourced in United Kingdom

Niopam 370 is a non-ionic, water-soluble iodinated contrast medium for use in radiographic examinations. It contains 370 milligrams of iodine per milliliter of solution.

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Lab products found in correlation

Ge vct 64 slice scanner, by GE Healthcare (1 mentions)

2 protocols using niopam 370

Coronary CT Angiography for Diabetes

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An optional scan of coronary computed tomographic angiography (CCTA) was offered to patients with diabetes to exclude obstructive coronary artery disease (>50% of luminal stenosis) and for assessment of epicardial fat volumes. CCTA was performed with a GE VCT 64 slice scanner (GE Healthcare, Little Chalfont, United Kingdom) and a Snapshot Pulse protocol with prospective electrocardiographic triggering. Participants received beta-blockade (intravenous metoprolol) and sublingual glyceryl trinitrate prior to the scan to achieve a heart rate of <65 beats/min. During the CCTA acquisition, 70 ml of iodinated contrast (Niopam 370, Bracco, High Wycombe, United Kingdom) was injected at a rate of 6 ml/s followed by a 50-ml saline flush. The scan covered a region from 1 to 2 cm above the left main coronary artery to 1 to 2 cm below the myocardial apex in a single breath hold.

Levelt E., Pavlides M., Banerjee R., Mahmod M., Kelly C., Sellwood J., Ariga R., Thomas S., Francis J., Rodgers C., Clarke W., Sabharwal N., Antoniades C., Schneider J., Robson M., Clarke K., Karamitsos T., Rider O, & Neubauer S. (2016). Ectopic and Visceral Fat Deposition in Lean and Obese Patients With Type 2 Diabetes. Journal of the American College of Cardiology, 68(1), 53-63.

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Multimodal Plaque Imaging Protocol

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The local institutional review board approved the entire study, and participants gave fully informed consent. Subjects with stable angina or acute coronary syndrome scheduled for percutaneous coronary intervention underwent both VH-IVUS and coronary CTA with data sets used initially for derivation and then validation of DECT plaque analysis. VH-IVUS was acquired with Eagle-Eye Gold catheters (Volcano Corporation, San Diego, CA) as described previously.⁸ (link) CT data were acquired with a Somatom Definition 64-slice dual-source machine (Siemens, Germany). Intravenous metoprolol was administered if heart rate was >65 beats/min. Images were acquired simultaneously at 140 kV, 82 mAs (tube A) and 100 kV, 164 mAs (tube B) with 64 × 0.6-mm collimation. A triphasic injection protocol with intravenous contrast (iopamidol [Niopam 370]; Bracco, UK) was used after a 20-mL timing bolus.

Obaid D.R., Calvert P.A., Gopalan D., Parker R.A., West N.E., Goddard M., Rudd J.H, & Bennett M.R. (2014). Dual-energy computed tomography imaging to determine atherosclerotic plaque composition: A prospective study with tissue validation. Journal of Cardiovascular Computed Tomography, 8(3), 230-237.

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