Rat anti human her2

Manufactured by Agilent Technologies

The Rat anti-human HER2 is a laboratory product designed for research purposes. It is an antibody that specifically binds to the human epidermal growth factor receptor 2 (HER2) protein. This product can be used in various research applications that involve the detection and study of HER2 expression.

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Lab products found in correlation

Mouse anti human cd3, by Agilent Technologies (2 mentions) Rat anti human granzyme b, by Thermo Fisher Scientific (2 mentions) Paraformaldehyde (pfa), by Boston BioProducts (2 mentions) Anti human nuclei, by Merck Group (1 mentions) Mouse anti human cd8, by Agilent Technologies (1 mentions)

Close spelling variants of this product

Anti-HER2 Anti-TM

2 protocols using rat anti human her2

Tumor Tissue Histopathological Analysis

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Tumor tissue was fixed for up to 3 days in 4% paraformaldehyde (Boston BioProducts) and stored in 70% ethanol until further processing. Histology was performed by the Pathology Core at City of Hope. Briefly, paraffin-embedded sections (10-µm) were stained with hematoxylin & eosin (H&E, Sigma-Aldrich), mouse anti-human CD3 (DAKO), mouse anti-human PSCA (Abcam), rat anti-human HER2 (DAKO), and rat anti-human Granzyme-B (eBioscience). Images were obtained using the Nanozoomer 2.0HT digital slide scanner and the associated NDP.view2 software (Hamamatzu).

Priceman S.J., Gerdts E.A., Tilakawardane D., Kennewick K.T., Murad J.P., Park A.K., Jeang B., Yamaguchi Y., Yang X., Urak R., Weng L., Chang W.C., Wright S., Pal S., Reiter R.E., Wu A.M., Brown C.E, & Forman S.J. (2017). Co-stimulatory signaling determines tumor antigen sensitivity and persistence of CAR T cells targeting PSCA+ metastatic prostate cancer. Oncoimmunology, 7(2), e1380764.

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Immunohistochemical Analysis of Brain Tissue

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Brain tissue was fixed for up to 3 days in 4% paraformaldehyde (Boston BioProducts) and stored in 70% ethanol until further processing. Histology was performed by the Pathology Core at City of Hope. Briefly, paraffin-embedded sections (10-μm) were stained with mouse anti-human CD3 (DAKO), mouse anti-human CD4 (DAKO), mouse anti-human CD8 (DAKO), rat anti-human HER2 (DAKO), rat anti-human Granzyme-B (eBioscience), and anti-human nuclei (Millipore) antibodies. Images were obtained using the Nanozoomer 2.0HT digital slide scanner and the associated NDP.view2 software (Hamamatzu).

Priceman S.J., Tilakawardane D., Jeang B., Aguilar B., Murad J.P., Park A.K., Chang W.C., Ostberg J.R., Neman J., Jandial R., Portnow J., Forman S.J, & Brown C.E. (2017). Regional Delivery of Chimeric Antigen Receptor–Engineered T Cells Effectively Targets HER2+ Breast Cancer Metastasis to the Brain. Clinical cancer research : an official journal of the American Association for Cancer Research, 24(1), 95-105.

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