All 97 of the enrolled patients underwent contrast-enhanced chest CT examination. The spiral CT equipment and scan parameters were as follows: GE Lightspeed Ultra 8-MDCT (120 kV, 230 mAs, reconstruction thickness 1.25 mm, reconstruction spacing 0.8 mm); GE Lightspeed 64-VCT (120 kV, 230 mAs, reconstruction thickness 1.25 mm, reconstruction spacing 0.8 mm); Toshiba Aquilion 64-MDCT (120 kV, 220 mAs, reconstruction thickness 1 mm, spacing 0.8 mm). The enhanced CT scan commenced at 35 s delay after intravenous injection of 85~100 mL of contrast medium (300 mg/mL) using a power injector at a rate of 2.5 mL/s.
Lightspeed vct 64
Manufactured by GE Healthcare
Sourced in United States, Germany
The Lightspeed VCT 64 is a 64-slice computed tomography (CT) scanner manufactured by GE Healthcare. It is designed to capture high-quality, detailed images of the body's internal structures. The scanner utilizes advanced technology to provide rapid image acquisition and reconstruction, enabling efficient and accurate diagnostic imaging.
Automatically generated - may contain errors
Lab products found in correlation
Brilliance 40, by Philips (7 mentions)
Discovery hd 750, by GE Healthcare (6 mentions)
Extended brilliance workspace, by Philips (5 mentions)
Lightspeed 16, by GE Healthcare (5 mentions)
Ultravist 370, by Bayer (4 mentions)
Aquilion one, by Toshiba (3 mentions)
Ict 256, by Philips (3 mentions)
Omnipaque, by GE Healthcare (2 mentions)
Brilliance 64, by Philips (2 mentions)
Iopamiro, by Bracco (2 mentions)
Aquilion one tsx 301c 320, by Toshiba (2 mentions)
Somatom definition as4 and as128, by Siemens (2 mentions)
Lightspeed pro 16, by GE Healthcare (2 mentions)
Mimics 20, by Materialise (1 mentions)
Icem cfd 15, by ANSYS (1 mentions)
Discovery ct750 hd scanner, by GE Healthcare (1 mentions)
Stellant, by Bayer (1 mentions)
Discovery ct750 hd, by GE Healthcare (1 mentions)
Somatom sensation 64, by Siemens (1 mentions)
Somatom spirit, by Siemens (1 mentions)
60 protocols using lightspeed vct 64
1
Contrast-Enhanced Chest CT Imaging Protocol
2
Finite element modeling of femur
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The finite element models of the full femur were created from the CT scans (tube current:120 mA, tube voltage: 100 kVP, and a resolution of 0.742X0.742X0.625 mm3) using a GE scanner (LightSpeed 64 VCT, GE Medical Systems, Milwaukee, WI, USA). The full femur of the right limb for the five cases was segmented in Mimics 20.0 (Materialise, Belgium). The segmented femora were then automatically meshed with 10-node tetrahedral element type (ICEM CFD 15.0, ANSYS Inc., PA, USA) with an average element size of 3mm. A mesh convergence study was conducted using four different element sizes (2, 2.5, 3, 3.5, 4 mm) on one subject (Case 2) as shown in Fig 2 . The values of first (e1) and third (e3) principal strains changed by only 4% and 3%, respectively, within the volume of interest (femoral neck) between the selected mesh refinement (3 mm) of 849,069 degrees of freedom (DOF) and the finest mesh (2 mm) of 2810736 degrees of freedom. Bone materials were defined as linear elastic isotropic. Heterogeneous material properties were estimated from the CT scan and mapped to the finite element models following a well-validated material-mapping procedure (Bonemat v3, Rizzoli Institute) [38 (link)–40 (link)]. ESP phantom was used for bone density calibration.
3
Radiological Assessment of Pelvic Fractures
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Patients were subjected to radiological examination according to the guidelines of Advanced Trauma Life Support (18 ). CT scanning was performed using a 64-slice multidetector CT scanner with automated tube current modulation (Lightspeed 64VCT; GE Healthcare) to determine the pelvic fracture type and other body system injuries on radiographs. A fellowship-trained orthopedic traumatologist with >10 years of experience and the institution's primary surgeon retrospectively classified the fractures according to the AO classification system.
4
Coronary CT Scans in Pacemaker Patients
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A total of 95 patients with pacemakers from multiple centers were enrolled in this study. There were 49 men and 46 women, mean age 65 ± 11 years (range 49 to 87 years), with a mean body mass index (BMI) of 23.39 (range 19.43 to 30.81). All patients were clinically diagnosed with definite or possible coronary heart disease. Forty-five and 50 patients underwent 64-slice (LightSpeed 64 VCT, GE Healthcare, Piscataway, NJ, USA) (64 group) and 640-slice (Aquilion ONE, Toshiba, Otawara, Japan) (640 group) CT coronary scans, respectively. No patients had severe renal insufficiency or a history of iodine allergy, and none were taking metoprolol to control their heart rate. Patients in both groups were divided into low and high heart rate groups, with 65 beats per minute (bpm) as the cut-off point according to the recommended collection scheme, because of the time slice resolution (175 ms) limitation of the device. Patients were also divided into normal pacing and arrhythmia groups, according to the pacing ECG.
5
Osteoporosis Fracture Risk Prediction
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The statistical models were developed based on a cohort of 100 Caucasian women who were at least 5 years post menopause, 50 of whom (55–89 years old) had suffered from a hip fracture and 50 selected to be pair matched in terms of age, height, and weight. Details of the cohort are extensively reported elsewhere46 (link) and presented in Table S4 (Supplementary Material). Due to incomplete CT data, 7 subjects were excluded from the analysis (Table 1 ). Informed written consent was obtained for all participants. The patients underwent QCT scans (LightSpeed 64 VCT, GE Medical Systems at 120 KVp/150 mA). For each acquired subject the scanned region included from above the femoral head to 3.5 cm below the lesser trochanter. For subjects having experienced a fracture, the contralateral femur was used for analysis, assuming that similar pathological or fracture-prone shape and density features were exhibited by the two femurs (none of the patients suffered from pathologies such as bone tumours or dysplasia). A data summary of the subjects here considered is reported in Table 1 .
Subjects’ clinical data.
| Fractured patients (46 subjects) | Non-fractured patients (47 subjects) | |||
|---|---|---|---|---|
| Mean | SD | Mean | SD | |
| Age | 75.4 | 9.1 | 74.6 | 9.0 |
| Mass (kg) | 63.2 | 15.2 | 64.2 | 12.2 |
| Height (cm) | 158.8 | 6.7 | 157.8 | 5.7 |
| aBMD (g/cm2) | 0.696 | 0.148 | 0.820 | 0.146 |
6
Contrast-Enhanced CT Imaging of the Abdomen and Pelvis
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All patients underwent abdominal and pelvic contrast-enhanced CT examinations, using either the LightSpeed 64 VCT (GE Medical Systems, Milwaukee, WI, USA) or Discovery CT750 HD scanner (GE Medical Systems), after fasting for more than 6 h. To reduce gastrointestinal motility, 10 mg of anisodamine (654-2; Hangzhou Minsheng Pharma, China) was intramuscularly administered 15–20 min prior to the CT examination. Next, 6 g of gas-producing crystals were orally administered with 10 mL of warm water shortly before the CT examination to distend the stomach. The patients were scanned in the supine position. The scan range was from the diaphragmatic dome to the lower margin of the pubis. The following imaging parameters were used: peak tube voltage, 120 kVp; tube current, automatic; collimation thickness, 64.000×0.625 mm; helical pitch, 0.984:1.000, and reconstructed thickness, 5 mm. A nonionic contrast material was injected through the antecubital vein at a rate of 3.5 mL/s (1.5 mL/kg of body weight; iohexol: 300 mg I/mL; Omnipaque, GE Healthcare). The arterial and venous phase scans were performed at 40 s and 70 s after the contrast media injection. The multiplanar reconstruction (MPR) images were obtained with a slice thickness of 5 mm.
7
Chest CT Scanning Protocol for Radiologists
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Chest CT scanning was performed using Brilliance 64 (Phillips Healthcare) or Light Speed 64VCT (GE Healthcare) following the standardized protocol. CT scanning was performed from the thoracic inlet to the level of bilateral adrenal glands in the supine position. Unenhanced CT scanning was first performed, and imaging parameters were as follows: tube voltage, 120 kVp; tube current, 100–250 mA; beam pitch, 0.516–0.98; slice thickness, 5 mm; and slice interval, 5 mm. For contrast-enhanced examination, the patients were injected with 80-110 mL (at a dosage of 1.5 mL/kg of body weight) nonionic contrast medium (iohexol 300 mg/mL; Omnipaque, GE Healthcare) + 30 mL physiological saline using a dual high-pressure injector (Stellant, Medrad, Indianola, USA) at a flow rate of 3.0 mL/s. Images of the arterial phase and delayed phase were obtained at 30 and 120 s after the start of injection, respectively. Subsequently, CT images were reconstructed into 0.625 or 1 mm slice thickness with a sharp reconstruction algorithm. All images were performed with both lung window (window width, 1500 HU; window level, −700 HU) and mediastinal window (window width, 375HU; window level, 50 HU).
8
Chest CT Imaging of Rabbits
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Rabbits in the experimental and control groups were placed in the prone position after intravenous injection of 3% pentobarbital sodium (2 mL/kg) for chest thin-layer CT on day 1 pre-inoculation and days 3 and 7 post-inoculation (GE light speed 64VCT, USA). Two independent experts evaluated the CT images.
9
Multimodal Imaging for Thyroid Lesion Evaluation
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An Aloka ProSound Alpha-5sv ultrasound system with a 7.5- to 12-MHz linear transducer (Hitachi Aloka Medical, LTD., Tokyo, Japan) was used for the neck ultrasound (neck US) examination. Neck US assessment is necessary to evaluate the composition and vascularity of the lesion in order to avoid necrotic spaces and vascular bundle and to select the most appropriate area of the mass for tissue sampling. For both procedures, a trans-isthmic or a lateral approach was performed according to each specific case.
A Lightspeed 16 RT, Lightspeed 64 VCT, and a Discovery HD 750 CT scan (GE Medical Systems, Waukesha, WI, USA) was used in patients scanned in our institution. Images of the total body CT scan were utilized for the evaluation of the tumor dimension; the presence of necrosis and/or calcifications; esophageal, tracheal, or laryngeal invasion; vascular involvement; and lymph node and/or distant metastases.
A Lightspeed 16 RT, Lightspeed 64 VCT, and a Discovery HD 750 CT scan (GE Medical Systems, Waukesha, WI, USA) was used in patients scanned in our institution. Images of the total body CT scan were utilized for the evaluation of the tumor dimension; the presence of necrosis and/or calcifications; esophageal, tracheal, or laryngeal invasion; vascular involvement; and lymph node and/or distant metastases.
10
Standardized Chest CT Imaging Protocol
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All patients underwent chest CT scanning using Light Speed 64VCT (GE Healthcare) and Brilliance 64 (Phillips Healthcare) following the standardized protocol. Scanning was performed from the top of the thoracic cavity to the level of bilateral adrenal glands. Helical scanning protocol was as follows: 120 kVp; 70–200 mAs; beam pitch, 0.516–0.98; slice thickness, 5 mm; slice interval, 5 mm; matrix, 512×512. Sections of 1 mm thickness were reconstructed with a sharp reconstruction algorithm. All images were displayed in both lung window (window width, 1500 HU; window level, −700 HU) and mediastinal window (window width, 400 HU; window level, 20 HU).
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